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900 labs · 77 student voices

Shinichiro Chuma, Associate Professor
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The Developmental Epigenome Lab works to understand and control the inheritance and reorganization of genomic and epigenomic information throughout the development of an individual. It focuses in particular on early development, pluripotent stem cells derived from early embryos, and the developmental cycle of germ cells. The lab is also part of the Human ES Cell Research Center, where it carries out quality control of pluripotent stem cells and develops new technologies. For the admission of graduate students, applicants are asked to contact the lab.

Gen Kondoh, Professor
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The Integrated Biological Processes Lab (Kondoh Lab) pursues research on the mechanisms of fertilization, the regulation of inflammatory helper T cells, and work that combines fertilization and immunology. Much remains unknown about how sperm acquire the ability to fertilize and how inflammatory helper T cells sustain inflammation in tissues. The lab explores the molecular mechanisms behind these processes in the body from a broad perspective. In particular, the lab creates genetically modified mice to clarify how important target molecules are in the body.

Hiroyuki Mori, Associate Professor
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The Biomembrane Systems Lab uses bacteria as model organisms to study, with a variety of methods, the fundamental membrane-related processes common to all life. The lab investigates how proteins are translated, folded, secreted, inserted into membranes, and degraded in the cell, as well as the stress response mechanisms that act when these processes go wrong. Using approaches such as biochemistry, biophysics, genetics, and structural biology, the lab aims to clarify how proteins at the cell surface of bacteria such as Escherichia coli and Vibrio species function and how their order is maintained.

VANDENBON Alexis, Associate Professor
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The Life Data Science Lab is an interdisciplinary team of researchers from diverse backgrounds, including bioinformatics, data science, and the life sciences. The lab develops methods to analyze and integrate single-cell and spatial transcriptomics data. It aims to understand the principles that determine the spatial arrangement and interactions of cells and the functions of tissues, as well as life phenomena that remain unexplained.

Kosuke Yusa, Professor
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The Stem Cell Genetics Lab (Yusa Lab) has developed CRISPR screening methods based on the genome-editing technology CRISPR-Cas9 and uses them for genetics in mammalian cells. The lab applies this technology to the biology of stem cells and cancer cells, aiming to contribute to regenerative medicine and cancer therapy through insights from basic biology.

Keiko Nonomura, Professor
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For organs such as the heart and lungs to function, it is important that mechanical factors such as volume and pressure change appropriately. The Mechanosensing Physiology Lab (Nonomura Lab) focuses on PIEZO channels, which underlie mechanoreception (mechanosensing), the detection of such mechanical changes, and works to clarify the role of mechanosensing in organ function, development, and disease.

Yukihiko Sugita, Associate Professor
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The Supramolecular Structure Lab was established in July 2026 within the Research Center for Infectious Disease Models, which is affiliated with the Institute for Life and Medical Sciences. Supramolecular complexes in viruses and cells function only when many molecules are precisely assembled. By making their three-dimensional structures visible at the atomic and molecular level, the lab aims to elucidate the mechanisms of biological phenomena and apply them to molecular design and drug discovery. The lab is not limited to virology; it collaborates with researchers in a wide range of fields that need structural information, both inside and outside the university and across academia and industry.

Eihachiro Kawase, Associate Professor
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The Clinical Foundation Lab was the first in Japan to succeed in establishing human ES cell lines, and its subsequent results are used not only for human ES cells but also for human iPS cells. Regenerative medicine that uses cells and tissues made from human ES cells and iPS cells (pluripotent stem cells) is entering the clinical trial stage worldwide. The lab develops the underlying technologies and establishes human ES cell lines for clinical use. Prospective graduate students are directed to contact the lab about admission.

Yoko Hamazaki, Professor
0 student voices
The immune system not only protects the body from infection, but is also deeply involved in the rejection of transplanted organs and in the onset of age-related diseases such as lifestyle-related diseases and cancer. The Hamazaki Lab mainly studies T cells, which act as the command center of the immune system, and the thymus, the organ that produces them. The lab aims to explore the basic principles of immunology and, building on them, develop new ways to control immunity, thereby contributing broadly to medicine and healthcare.

Yoshiya Kawaguchi, Professor
0 student voices
iPS cells can be used to reproduce organ development in a culture dish to make cells for transplantation, and to reproduce disease mechanisms to aid drug development. However, for diseases involving many types of cells, it is difficult to reproduce the disease state with iPS cells alone, and model animals such as mice are also indispensable. The Kawaguchi Lab studies endoderm-derived organs, including the pancreas, carrying out research using iPS cells and research on organ regeneration, aging, and cancer at the same time. This is because organ development and the cell behavior seen in regeneration, aging, and cancer share common features, such as active proliferation and cell migration.
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