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Faculties at Kyoto University ›

Keizo Tomonaga, Professor
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Every virus multiplies and spreads by skillfully exploiting the machinery of the organism it infects. Understanding viruses leads not only to understanding their pathogenicity and survival strategies, but also to clarifying how life itself works. Viruses, which infect every kind of organism on Earth, are also thought to have been indispensable partners in our evolution. The RNA Virus Lab (Tomonaga Lab) takes "understanding viruses to explore life" as its research goal.

Takeshi Noda, Professor
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The Ultrastructural Virology Lab (Noda Lab) focuses on viruses that cause disease in humans, such as influenza virus, Ebola virus, and Lassa virus, and aims to elucidate how they replicate inside cells and how they cause disease. The lab specializes in visual analysis using various electron microscopy methods, including cryo-electron microscopy, and can reveal the structures of virus particles and infected cells at a range of resolutions. The lab also incorporates techniques from other fields, such as structural biology and developmental biology.

Hiroyuki Sakai, Associate Professor
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The Cancer Virology Lab (Sakai group) studies virus–cell interactions in detail, aiming to elucidate how viral infection causes cancer and to develop ways to control it. Its main research subject is human papillomavirus, which causes cervical cancer. Regarding the admission of graduate students, prospective applicants are advised to contact the lab.

Daisuke Morita, Assistant Professor
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The Cell Regulation Lab studies immunology from a new angle called "lipid immunity." Unlike conventional T cells that recognize proteins (peptides), there are known to be T cells that recognize lipids and lipid-linked peptides. The lab aims to elucidate the full picture of this new form of immunity and to develop new lipid vaccines. Regarding the admission of graduate students, prospective applicants are advised to contact the lab.

Akihisa Kato, Professor
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The Viral Molecular Pathogenesis Lab (Kato Lab) studies large DNA viruses such as herpes simplex virus and cytomegalovirus, working to understand infectious diseases and to uncover biological phenomena. Viruses not only cause disease but also serve as a "mirror of life" that reveals hidden, unknown rules of living systems. The lab analyzes the battle between viruses and their hosts at the molecular level, aiming to discover principles of life not yet in textbooks and to create new treatments. The lab welcomes anyone who wants to take on the mysteries of life, regardless of background.

Hiroshi Kawamoto, Professor
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In hematopoiesis, the differentiation potential of multipotent hematopoietic stem cells becomes progressively restricted, giving rise to progenitor cells of various lineages. The Regenerative Immunology Lab (Kawamoto Lab) aims to analyze the mechanisms that determine the fate of progenitor cells in this process, with particular emphasis on the pathway leading to T cells. The lab also conducts research on the evolutionary origins of blood cells. The lab is also developing cancer treatments that use T cells regenerated from iPS cells or ES cells, and is preparing a clinical trial targeting acute myeloid leukemia.

Shinichiro Chuma, Associate Professor
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The Developmental Epigenome Lab works to understand and control the inheritance and reorganization of genomic and epigenomic information throughout the development of an individual. It focuses in particular on early development, pluripotent stem cells derived from early embryos, and the developmental cycle of germ cells. The lab is also part of the Human ES Cell Research Center, where it carries out quality control of pluripotent stem cells and develops new technologies. For the admission of graduate students, applicants are asked to contact the lab.

Gen Kondoh, Professor
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The Integrated Biological Processes Lab (Kondoh Lab) pursues research on the mechanisms of fertilization, the regulation of inflammatory helper T cells, and work that combines fertilization and immunology. Much remains unknown about how sperm acquire the ability to fertilize and how inflammatory helper T cells sustain inflammation in tissues. The lab explores the molecular mechanisms behind these processes in the body from a broad perspective. In particular, the lab creates genetically modified mice to clarify how important target molecules are in the body.

Hiroyuki Mori, Associate Professor
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The Biomembrane Systems Lab uses bacteria as model organisms to study, with a variety of methods, the fundamental membrane-related processes common to all life. The lab investigates how proteins are translated, folded, secreted, inserted into membranes, and degraded in the cell, as well as the stress response mechanisms that act when these processes go wrong. Using approaches such as biochemistry, biophysics, genetics, and structural biology, the lab aims to clarify how proteins at the cell surface of bacteria such as Escherichia coli and Vibrio species function and how their order is maintained.

VANDENBON Alexis, Associate Professor
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The Life Data Science Lab is an interdisciplinary team of researchers from diverse backgrounds, including bioinformatics, data science, and the life sciences. The lab develops methods to analyze and integrate single-cell and spatial transcriptomics data. It aims to understand the principles that determine the spatial arrangement and interactions of cells and the functions of tissues, as well as life phenomena that remain unexplained.
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