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Developmental Epigenome Lab
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A lab that explores how genomic information is inherited and protected from fertilization to the next generation.
AboutAbout the lab
Inheritance and reorganization of the genome and epigenome.
The Developmental Epigenome Lab works to understand and control the inheritance and reorganization of genomic and epigenomic information throughout the development of an individual.
It focuses in particular on early development, pluripotent stem cells derived from early embryos, and the developmental cycle of germ cells. The lab is also part of the Human ES Cell Research Center, where it carries out quality control of pluripotent stem cells and develops new technologies.
For the admission of graduate students, applicants are asked to contact the lab.
Key terms
- Epigenome
- The full set of chemical marks that switch gene activity on and off without changing the DNA sequence
- Germ cell
- A cell that passes genetic information to the next generation, such as sperm and egg
- Genetic stability
- The maintenance of genetic information without change as cells divide
ResearchResearch themes
The lab is working to clarify how developmental and differentiation programs relate to the control of genetic stability, and explores the possibility of reconstituting that relationship.
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MembersFaculty
- Associate ProfessorShinichiro Chuma
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “0300 Flourescence Stained new” OpenStax / CC BY 4.0 (cropped)
- Development and genetic stability: “208031 EPFL David Suter Sox2” EPFL-MEDIACOM / CC BY 4.0 (cropped)
- Related lab (再生免疫学分野): “Methicillin-resistant Staph bacteria ( )” NIH Image Gallery from Bethesda, Maryland, USA / Public domain (cropped)
- Related lab (統合生体プロセス分野): “Spermatozoa-human-1000x” No specific author / Public domain (cropped)
- Related lab (臨床基盤分野): “DNA biochemistry ( )” Oak Ridge National Laboratory / CC BY 2.0 (cropped)
- Related lab (幹細胞遺伝学分野): “Cas9 5AXW plain” Thomas Splettstoesser (www.scistyle.com) / CC BY-SA 4.0 (cropped)
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