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Clinical Foundation Lab
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The lab that created Japan's first human ES cells develops cells and technologies for regenerative medicine.
AboutAbout the lab
Human ES cells ready for clinical use.
The Clinical Foundation Lab was the first in Japan to succeed in establishing human ES cell lines, and its subsequent results are used not only for human ES cells but also for human iPS cells.
Regenerative medicine that uses cells and tissues made from human ES cells and iPS cells (pluripotent stem cells) is entering the clinical trial stage worldwide. The lab develops the underlying technologies and establishes human ES cell lines for clinical use.
Prospective graduate students are directed to contact the lab about admission.
Key terms
- ES cells
- Stem cells made from fertilized eggs that can become almost all cell types in the body
- Pluripotent stem cells
- Stem cells, such as ES cells and iPS cells, that can become most types of cells in the body
- Culture substrate
- A substance that serves as a scaffold for cells to attach to when they are grown
ResearchResearch themes
The lab establishes clinical-grade human ES cell lines, produces stocks of them and distributes them to research facilities, and develops the underlying technologies for this work.
*Illustrative imageEstablishing human ES cell lines for clinical use
At the institute's cell processing facility, the lab establishes human ES cell lines usable in clinical settings, produces stocks, and distributes them to facilities conducting clinical research.
*Illustrative imageEfficient culture methods for human pluripotent stem cells
In a collaborative study, the lab found that a small fragment of laminin is a suitable culture substrate, and showed that cells proliferate and survive more efficiently on it. This fragment has been commercialized and is used around the world.
MembersFaculty
- Associate ProfessorEihachiro Kawase
- Program-Specific Assistant ProfessorKei Takada
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “DNA biochemistry ( )” Oak Ridge National Laboratory / CC BY 2.0 (cropped)
- Establishing human ES cell lines for clinical use: “Human iPS cells colonies” Christine Hale, Amy Yeung, David Goulding, Derek Pickard, Kaur Alasoo, Fiona Powrie, Gordon Dougan / CC BY 4.0 (cropped)
- Efficient culture methods for human pluripotent stem cells: “Pile of culture flask ( )” Jean-Etienne Minh-Duy Poirrier from USA / CC BY-SA 2.0 (cropped)
- Related lab (発生エピゲノム分野): “0300 Flourescence Stained new” OpenStax / CC BY 4.0 (cropped)
- Related lab (再生免疫学分野): “Methicillin-resistant Staph bacteria ( )” NIH Image Gallery from Bethesda, Maryland, USA / Public domain (cropped)
- Related lab (微細構造ウイルス学分野): “Influenza A Virus (H3N )” NIAID / CC BY 2.0 (cropped)
- Related lab (幹細胞遺伝学分野): “Cas9 5AXW plain” Thomas Splettstoesser (www.scistyle.com) / CC BY-SA 4.0 (cropped)
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