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703 labs · 51 student voices

Midori Shimada, Professor
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The Shimada Lab studies everything from how genetic information is inherited and its expression regulated to the search for therapeutic targets in cancer and the development of treatment strategies. Targeting hard-to-treat cancers such as breast and prostate cancer, the lab examines proteins involved in cancer cell proliferation to find therapeutic targets. The lab also studies biological phenomena caused by proline isomerization, the link between abnormal calcium signaling and cancer, and the mechanisms that keep the genome stable. Third-year medical students are assigned to the lab through the Basic Medicine Seminar, and graduate students are recruited on an ongoing basis.

Tetsuya Okajima, Professor
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The Molecular and Cellular Biochemistry Lab (Department of Biochemistry II) studies molecules involved in the onset and progression of cancer and neurodegenerative diseases, and their post-translational modifications. Focusing on the structure and function of receptor proteins on the cell membrane surface, their ligands, and the glycans that modify them, the lab analyzes them using biochemistry, molecular biology, and cell biology. The lab aims to develop new therapies based on how molecules function and are regulated. On the lab's website, it is introduced under the name "Molecular and Cellular Biochemistry and Functional Molecule Regulation."

Shinya Toyokuni, Professor
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The Pathology and Biological Responses Lab studies broadly and in depth what oxidative stress means for living organisms, from the cellular level to the level of the human individual. While valuing the morphological approach that is characteristic of pathology, the lab carries out its research using methods from genetics, cell engineering, and genetic engineering. Students can gain broad morphological knowledge needed to analyze genetically modified animals, and those with an MD (medical doctor) degree can, if they wish, also receive basic training as a pathologist in parallel. The lab welcomes students with a deep interest in oxidative stress, regardless of their original field.

Atsushi Enomoto, Professor
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The Tumor Pathology / Molecular Pathology Lab aims to train board-certified pathologists and to develop pathology research that is as original as possible. Through graduate research, the lab aims to train pathologists who can set their own morphology-based research questions. Centered on functional analysis of molecules and morphology, the lab conducts research with members from diverse backgrounds. The training of board-certified pathologists is supported by the Division of Pathology at Nagoya University Hospital and affiliated hospitals.

Keigo Shibayama, Professor
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The Molecular Pathogenic Bacteriology (Bacteriology) Lab studies the virulence factors and drug resistance mechanisms of pathogenic bacteria that cause problems in healthcare-associated and community-acquired infections. Its subjects include Staphylococcus species including MRSA, Streptococcus species, Enterobacteriaceae species such as Escherichia coli and Klebsiella pneumoniae, and glucose non-fermenting bacteria such as Pseudomonas aeruginosa. In addition to basic bacteriological analysis, the lab also makes use of genetic analysis and proteome analysis. The lab aims to produce results that contribute to the diagnosis, prevention, and treatment of bacterial infections.

Hiroyoshi Nishikawa, Professor
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The Molecular and Cellular Immunology Lab studies the immune system and the diseases caused by its abnormalities, ranging from basic research to translational research. The immune system not only eliminates non-self substances such as microorganisms, but also helps maintain the state of the body and is involved in the establishment of pregnancy. In cancer, the immune system eliminates abnormal cells (immune surveillance), while cancer cells escape from the immune system (immune escape) and the disease progresses. The lab aims to connect its research to an understanding of the path from immune surveillance to immune escape, one of the most important issues in immunology.

Hiroshi Kimura, Professor
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The Virology Lab studies viruses that cause disease in humans, such as herpesviruses and influenza virus. The lab works to clarify how viruses cause disease and to develop methods for diagnosing, controlling, and treating viral diseases. Viruses cause severe infectious diseases and can also cause cancers such as liver cancer and malignant lymphoma. The lab is part of the Department of Microbiology and Immunology in the Graduate School of Medicine.

Akira Ishii, Professor
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The Forensic Medicine and Bioethics Lab works on forensic medicine, which studies medical matters that raise legal issues. The lab performs expert forensic examinations in actual criminal cases and addresses the research questions that emerge through this casework. Currently, it focuses on forensic toxicology research using mass spectrometers and on studies of toxicity mechanisms using omics. The lab is open not only to students from medical backgrounds but also to students from other faculties who are interested in forensic practice and research.

Masashi Kato, Professor
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The lab studies how the environment affects health and develops methods of prevention. Centered on molecular biology, the lab carries out "molecular toxicology research" that analyzes the mechanisms by which the environment induces disease. In addition to experimental medicine research using animals and cells, the lab also conducts fieldwork research, including epidemiology, so students can do research that fits their own aptitudes. For those considering graduate school, the lab accepts inquiries at any time so that they can see the research firsthand and try part of it before deciding on a field of specialization.

Kenji Wakai, Professor
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The lab investigates the causes of cancer and other diseases, centered on large-scale cohort studies. It is an education and research group that carries on the Department of Preventive Medicine established in 1941, and its research themes have shifted from infectious diseases such as tuberculosis and diphtheria to cardiovascular disease, cancer, and intractable diseases. The lab serves as the central office of the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study), which began in 2005.
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