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Preventive Medicine Lab
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A preventive medicine lab that investigates the causes of cancer and other diseases through large-scale cohort studies.

AboutAbout the lab
Carrying on the principles of preventive medicine to investigate the causes of disease
The lab investigates the causes of cancer and other diseases, centered on large-scale cohort studies.
It is an education and research group that carries on the Department of Preventive Medicine established in 1941, and its research themes have shifted from infectious diseases such as tuberculosis and diphtheria to cardiovascular disease, cancer, and intractable diseases.
The lab serves as the central office of the Japan Multi-Institutional Collaborative Cohort Study (J-MICC Study), which began in 2005.
Key terms
- Cohort study
- Research in which many people take part and are followed over a long period to track the later occurrence of disease and other outcomes, in order to study links with lifestyle habits and other factors.
- Genetic polymorphism
- Differences in gene types that vary from person to person. They provide clues for studying susceptibility to disease and constitution.
- Case-control study
- A research method that compares people who have developed a disease with those who have not, in order to identify factors involved in the development of the disease.
- Smoking cessation intervention
- A technique that healthcare providers can use briefly and at low cost to guide smokers toward quitting.
ResearchResearch themes
The lab investigates the causes of cancer and other diseases through cohort studies and analysis of genotypes. It also studies occupational health management and methods for helping smokers quit.
*Illustrative imageCohort studies of cancer
The lab has served as the office for the JACC Study, a cancer cohort study. It examines the associations between common cancers and lifestyle habits, as well as associations with biomarkers measured in serum collected at enrollment.
*Illustrative imageGenotypes and disease risk
The lab searches for genotypes related to the risk of developing disease and examines their interactions with lifestyle habits using case-control study methods. Its targets include genetic polymorphisms related to gastric mucosal atrophy and genotypes related to smoking habits.
*Illustrative imageCauses of diseases arising in the workplace
The lab investigates the causes of health problems among people in the prime of their working lives in occupational settings where it has long been involved in health management. In addition to risk factors for cardiovascular diseases such as hypertension and for cancer, it has recently been working with psychiatrists to consider workplace measures for mental health.
*Illustrative imageEvaluating the effectiveness of smoking cessation interventions
The lab examines the effectiveness of smoking cessation interventions, which help smokers quit, among patients, residents, and employees. It uses methods such as measuring exhaled carbon monoxide concentration and notifying participants of the results of genetic polymorphism testing.
MembersFaculty
The lab's members include faculty, researchers, doctoral and master's students, graduate research students, and administrative and research support staff.As of 2025
- ProfessorKenji Wakai
- Associate ProfessorTakashi Tamura
- LecturerMako Nagayoshi
- Project Assistant ProfessorTakashi Matsunaga
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Checking Blood Sample ( )” National Eye Institute / CC BY 2.0 (cropped)
- Cohort studies of cancer: “742 Medical Records - DPLA - 39b55c9f8c506e0d3d4f6522a01d2906 (page 3)” Department of Defense. Department of the Army. Office of the Surgeon General. U.S. Army Medical Command. Fitzsimons Army Medical Center. (10/2/ ) / Public domain (cropped)
- Genotypes and disease risk: “DNA Double Helix by NHGRI” National Human Genome Research Institute / Public domain (cropped)
- Causes of diseases arising in the workplace: “HK TST East Hong Kong Science Museum Occupational Safety & Health Council OSHC Jack figure Occupational Safety & Health Council workplace Porters labour at work Jan-2012” Boboworkplace / CC BY-SA 3.0 (cropped)
- Evaluating the effectiveness of smoking cessation interventions: “CO Breath Test Monitor” Mdd2018 / CC BY-SA 4.0 (cropped)
- Related lab (Human Augmentation and Hand Surgery Lab): “Surgical instruments used in gynecology” GiftedLydia / CC BY-SA 4.0 (cropped)
- Related lab (Nephrology Lab): “HCCH hemodialysis machine” Jackhsiao / Public domain (cropped)
- Related lab (Pediatric Surgery Lab): “Reserve Citizen Airmen build partnerships in operating room (8948139)” U.S. Air Force 94AW by Maj. Stephani Schafer / Public domain (cropped)
- Related lab (Dermatology (Pathophysiology of Skin Diseases) Lab): “IDS-1100 Dermatoscope” Abessemans94 / CC BY-SA 4.0 (cropped)
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