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Forensic Medicine and Bioethics Lab
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The forensic medicine lab uses mass spectrometry to analyze drugs and poisons and to explore how poisoning occurs.
AboutAbout the lab
Tackling issues found in forensic casework with mass spectrometry and omics
The Forensic Medicine and Bioethics Lab works on forensic medicine, which studies medical matters that raise legal issues.
The lab performs expert forensic examinations in actual criminal cases and addresses the research questions that emerge through this casework.
Currently, it focuses on forensic toxicology research using mass spectrometers and on studies of toxicity mechanisms using omics.
The lab is open not only to students from medical backgrounds but also to students from other faculties who are interested in forensic practice and research.
Key terms
- Mass spectrometer
- An instrument that identifies and measures substances by their mass. The lab uses GC-MS/MS and LC-MS/MS
- Omics
- Analytical technologies that comprehensively examine metabolites, RNA, and proteins
- Metabolomics
- A technology for comprehensively analyzing endogenous metabolites such as amino acids, fatty acids, sugars, and nucleic acids
ResearchResearch themes
Forensic medicine is the study of medical matters that raise legal issues, and it covers an extremely wide field. Based on issues that emerge from forensic casework, the lab studies methods for analyzing drugs and poisons and the mechanisms by which toxicity appears.
*Illustrative imageAnalyzing drugs and poisons with mass spectrometry
The lab studies highly sensitive methods for analyzing drugs and poisons in biological samples using mass spectrometers. Its targets are wide-ranging, from illegal drugs to natural toxins, and it works on building a mass spectrometry database of natural toxins and on methods for distinguishing isomers of illicit drugs.
*Illustrative imageExploring toxicity mechanisms from metabolites
Combining animal experiments in rats and mice with metabolomics, the lab studies the mechanisms of acute poisoning death caused by drugs and poisons, how dependence develops on addictive drugs, and the pathology of sudden death. Recently, it has also added comprehensive analysis of RNA and proteins.
MembersFaculty
The members of the Forensic Medicine and Bioethics Lab consist of a Professor and an Assistant Professor.
- ProfessorAkira Ishii
- Assistant ProfessorYujin Natori
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Ion chromatograph in combination with a mass spectrometer, in CAFIA laboratory, Czech Republic” Sarka Na kopci / CC BY-SA 4.0 (cropped)
- Analyzing drugs and poisons with mass spectrometry: “Agilent 6538 Ultra High Definition (UHD) Accurate-Mass Q-TOF” Michael Pereckas from Milwaukee, WI, USA / CC BY 2.0 (cropped)
- Exploring toxicity mechanisms from metabolites: “Metabolomic analyses ( )” Oak Ridge National Laboratory / CC BY 2.0 (cropped)
- Related lab (Molecular Pathogenic Bacteriology Lab (Bacteriology)): “Inoculating loop and wire used in Microbiology Laboratory” Ajay Kumar Chaurasiya / CC BY-SA 4.0 (cropped)
- Related lab (Clinical Research Education Lab): “Stethoscope 1” ernstl / CC BY-SA 2.0 (cropped)
- Related lab (Molecular and Cellular Biochemistry (Biochemistry II) Lab): “Biochemistry Lab - Tirunelveli Medical College” Kallidaimaniac (talk) / Public domain (cropped)
- Related lab (Pathology and Biological Responses Lab (Pathology I)): “Scientist are at the Biomedical Research Laboratory Center 04” Oloyedegk / CC BY-SA 4.0 (cropped)
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