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900 labs · 77 student voices

Haruo Ogawa, Professor
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The lab aims to elucidate, through analysis of protein three-dimensional structures, the molecular mechanisms of biological phenomena that underlie drug discovery. Since the 2026 academic year, the lab has been led by Prof. Ogawa. The goal is not simply to determine three-dimensional structures but to reveal the principles behind their functions. Now that the structures of membrane receptors and transporters can be visualized, "structural pharmacology," which understands drug action at the structural level, has become a reality. The lab actively adopts cryo-electron microscopy and takes on determining the structures of molecules that are difficult to analyze.

Shiori Sekine, Professor
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Mitochondria are not only the cell's largest site of energy production but also organelles that carry out diverse functions, including the synthesis of small molecules such as iron-containing cofactors, heat production in the body, cell death, and immune responses. The lab tackles the fundamental question: "How do mitochondria sense changes in their environment and convert them into cellular responses?" In particular, the lab focuses on "fluctuations of small molecules in the body" and "mitochondrial stress," combining molecular biology, cell biology, and genetics with comprehensive analyses such as proteomics and metabolomics.

Takao Hashiguchi, Professor
0 student voices
Infectious diseases remain a threat to children around the world. The Division of Virus Control (Hashiguchi Lab) studies viral infectious diseases that affect children. The lab focuses in particular on clarifying how viruses enter cells and how compounds, peptides, glycans, and antibodies block that entry. The research combines virology, structural biology, and computer science.

Yoshinaga Ito, Professor
0 student voices
It has become clear that the immune system does more than eliminate pathogens: it actively interacts with the body's own tissues and plays an important role in maintaining homeostasis. The Division of Pathogenic Immunology clarifies the physiological role of immune responses against the body's own tissues and the mechanisms of diseases that arise when they break down, with the aim of developing new treatments. The lab views autoimmune diseases and cancer from a unified perspective, as malfunctions of immune responses against the body's own tissues, and confirms in human samples the mechanisms revealed in mouse models.

Eriko Kage-Kage-Nakadai, Professor
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The Division of Aging and Infection Control uses the nematode C. elegans and mice as model organisms to study the mechanisms of aging and infection and ways to control them. Inflammation is increasingly recognized as deeply linked not only to infection but also to a variety of chronic diseases, and the lab is also looking at the possibility of suppressing inflammation with gut bacteria.

Tatsushi Igaki, Professor
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Much has been learned about how individual cells behave, but how cells communicate with one another to produce the functions of a cell population is still largely unknown. The Multicellular Systems division (Igaki Lab) focuses on competition and cooperation between cells. It aims to uncover the principles of cell-cell communication that underlie organ development and tissue maintenance, as well as the mechanisms of cancer and aging that arise when this communication breaks down. The lab uses Drosophila fruit flies, which are well suited to genetics and imaging, as its model organism, and applies the principles it discovers to mammalian cells and mice through collaborations.

Miki Imanishi, Professor
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The human body is built on the elaborate interactions of many kinds of biomolecules. The Biofunctional Chemistry division aims to understand biomolecular interactions from a chemical perspective, create proteins that control cell functions and genes, and establish new ways of thinking about treatment. The lab uses methods from molecular biology, cell biology, and peptide and protein chemistry.

Fumiyoshi Yamashita, Professor
0 student voices
Drugs are given to real patients who differ greatly in genetic background, living environment, and health condition. As a result, even drugs whose efficacy and safety have been confirmed in clinical trials may have limited effects, or may cause side effects from drug-drug or drug-food interactions, or unexpected side effects. The Mathematical Therapeutics division aims to identify the causes of these risks and to establish methods for assessing risk in drug development, formulation technologies that avoid risk, and methods for designing and monitoring dosing in clinical practice.

Daiki Hira, Associate Professor
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Precision medicine, which prevents and treats disease by taking into account individual differences in genetic information, living environment, and lifestyle, is attracting growing attention. The Clinical Pharmacy Education lab conducts two kinds of research: building a scientific foundation for solving problems found in actual drug therapy, and developing new drug therapies from the results of basic research. Its aim is to develop personalized treatment that is optimal for each patient. The lab conducts research together with the Department of Pharmacy at Kyoto University Hospital (Medical Pharmaceutics field).

Hiroyuki Kimura, Professor
0 student voices
The Disease Molecular Control field is a cooperating division of the Department of Pharmacy in the Graduate School of Pharmaceutical Sciences, staffed by faculty of the Radiation Control Division of the Environment, Safety and Health Organization. The faculty's research fields span pharmaceutical chemistry and drug discovery science, radiation science and diagnostic imaging, and pharmaceutical analytical chemistry.
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