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900 labs · 77 student voices
Jun Saito, Professor
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The Saito Lab uses disease-specific iPS cells made from the cells of patients with rare, hard-to-treat diseases to analyze disease mechanisms and develop treatments. Many rare intractable diseases that begin in childhood have unknown causes and no known treatments, and the suffering can last a lifetime. For diseases that cannot be studied adequately in mice or cultured cells, using patients' iPS cells is effective. The lab mainly targets immune diseases (immunodeficiencies and autoinflammatory syndromes), blood diseases (such as bone marrow failure), and neuromuscular diseases (spinal muscular atrophy).
Shimpei Gotoh, Professor
0 student voices
The respiratory system is divided into two regions: the airways and the alveoli. The airways perform mucociliary clearance, which removes foreign particles and pathogens, while the alveoli perform gas exchange of oxygen and carbon dioxide. The Gotoh Lab develops technologies to generate airway and alveolar cells from iPS cells, aiming for clinical applications. The shortage of donors for lung transplantation is a serious problem worldwide. Taking advantage of the fact that iPS cells can provide as many lung cells as needed, the lab seeks to turn this into technologies useful for diagnosis and treatment.
Yoshinori Yoshida, Associate Professor
0 student voices
The Yoshida Lab uses iPS cell technology to conduct research on regenerative medicine and drug discovery for the heart. Its work ranges widely from basic research at the molecular level to translational research with clinical application in view.
Makoto Ikeya, Associate Professor
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To use iPS cells in medicine, whether for cell transplantation, elucidating diseases, or drug discovery, it is essential to have methods for producing the target cells reliably and easily. The Ikeya Lab develops methods for inducing differentiation of cells that are difficult to make or for which simpler, more efficient methods are needed. In particular, it focuses on cells at intermediate stages of development, and develops methods that mimic the environment in the body to induce the target cells step by step, as well as culture methods that maintain the cells at each stage as stem cells. Using these technologies, the lab aims to develop new treatments for intractable diseases.
Hidetoshi Sakurai, Associate Professor
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The Sakurai Lab aims to establish treatments for intractable muscle diseases, especially muscular dystrophy. There are two routes to treatment: cell transplantation therapy using progenitor cells made from iPS cells, and drug development that recreates the disease in vitro using patients' iPS cells.
Sayako Katada, Associate Professor
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The Katada Lab studies how the fate of neural stem cells is determined and the diverse functions of the choroid plexus, which produces cerebrospinal fluid, aiming to understand everything from brain development to neurological diseases. The choroid plexus secretes various factors into cerebrospinal fluid and is involved in the development and maintenance of the brain. It also serves as a barrier between the blood and cerebrospinal fluid, mediating the exchange of information between the body and the brain, but much of its function remains unknown. In addition to basic research using mice, the lab creates cerebral cortex and choroid plexus organoids from the iPS cells of patients with neurological diseases and analyzes them.
Misao Fujita, Professor
0 student voices
Research toward the clinical application of human iPS cells is now moving into full swing. To advance this research both quickly and soundly, the cooperation and understanding of society, starting with the people who take part in the research, are essential. The Fujita Lab investigates ethical regulations and policies in Japan and abroad, as well as public attitudes and actual practices, concerning the challenges of regenerative medicine and cell therapy, chimeric animals made with human iPS cells, and germ cells derived from iPS cells. It works to organize the ethical, legal, and social issues involved and to propose ways of addressing them.
Jusaku Minari, Associate Professor
0 student voices
Advanced life sciences such as iPS cell research and genome research are making great progress. For practical application, it is necessary to consider not only the scientific research itself but also its impact on society. The Minari Lab values social perspectives and diversity of opinion, and considers how the benefits of advanced life sciences can be delivered to (future) society.
Shinya Yamamoto, Professor
0 student voices
The Yamamoto Lab studies the mystery of the evolution of intelligence in a wide range of animals, combining cognitive research in captivity with fieldwork in the wild. It is particularly interested in social intelligence, the intelligence exercised within society. Its key words are empathy, understanding others, cooperation, culture, and group society. The lab also works toward a better society of coexistence between animals and humans. For graduate study, the lab is part of the Graduate School of Science, Division of Biological Sciences (Primatology and Wildlife Science group), and accepts students through the professor's role as a graduate-level faculty member of the Wildlife Research Center.
Naoko Tokuchi, Professor
0 student voices
The Silviculture Lab uses knowledge gained through fieldwork to work on projections of forest productivity, carbon storage, and related topics. The lab is based in research forests and experimental sites ranging from the Hokkaido Research Forest to the Tokuyama Experimental Site in Yamaguchi Prefecture, as well as in many other forests in Japan and abroad. For graduate study, the lab is a cooperating chair of the Division of Forest Science in the Graduate School of Agriculture, and its research is led by faculty of the Field Science Education and Research Center.
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