LAB LOGA page on LabLog, a review site (not the lab's official page)
Yoshida Lab
Machine-translated · View original
The lab uses iPS cells to make hearts, advancing regenerative medicine and drug discovery for heart disease.
AboutAbout the lab
Transforming cardiac medicine with iPS cells
The Yoshida Lab uses iPS cell technology to conduct research on regenerative medicine and drug discovery for the heart.
Its work ranges widely from basic research at the molecular level to translational research with clinical application in view.
Key terms
- Cardiomyocytes
- Muscle cells that make the heart beat
- Disease-specific iPS cells
- iPS cells made from the cells of patients with a disease. They can reproduce the disease state in a culture dish
- Cardiac organoids
- Small, three-dimensional, heart-like tissues cultured from stem cells
- Epicardium
- The membrane covering the outermost layer of the heart. It is the source of the heart's non-cardiomyocyte cells
ResearchResearch themes
The lab's work rests on three pillars: developing regenerative medicine, modeling heart disease and drug discovery, and controlling the maturation of differentiated cells.
*Illustrative imageRegenerative therapy for heart muscle
Aiming for a next-generation treatment for patients with conditions such as severe heart failure, the lab works toward realizing regenerative therapy for heart muscle using iPS cells. It studies how transplanted cardiomyocytes engraft, and is conducting studies in medium-sized animals in preparation for clinical trials.
*Illustrative imageHeart disease models and drug discovery
Using disease-specific iPS cells from patients with cardiomyopathy, arrhythmia, and other conditions, the lab aims to analyze disease mechanisms and develop therapeutic drugs.
*Illustrative imageMaking heart cells suited to the purpose
Heart muscle comes in various types, such as ventricular and atrial muscle, and it is important to produce each type selectively according to the purpose. The lab has also established a method for producing mature epicardial cells.
MembersFaculty
- Associate ProfessorYoshinori Yoshida
- Program-Specific Assistant ProfessorShunsuke Funakoshi
- Specially Appointed Assistant ProfessorHisayuki Amano
- Specially Appointed Assistant ProfessorYuya Fujiwara
- Hospital Assistant ProfessorKazuhisa Chonabayashi
- Hospital Assistant ProfessorMakoto Watanabe
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Yoshida Lab
Katada LabCenter for iPS Cell Research and Application, Department of Clinical ApplicationFate determination of neural stem cells and functions of the…
Sakurai LabCenter for iPS Cell Research and Application, Department of Clinical ApplicationTreatment of intractable muscle diseases, especially muscula…
Kaneko LabCenter for iPS Cell Research and Application, Department of Clinical ApplicationImmune regenerative therapy using the properties of iPS cell…
Ikeya LabCenter for iPS Cell Research and Application, Department of Clinical ApplicationMedical applications of iPS cells include cell transplantati…The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Anatomy Heart Latin Tiesworks” Tvanbr / Public domain (cropped)
- Regenerative therapy for heart muscle: “1020 Cardiac Muscle” OpenStax / CC BY 4.0 (cropped)
- Heart disease models and drug discovery: “Didactic model of an amphibian heart-FMVZ USP-14” Wagner Souza e Silva / CC BY-SA 4.0 (cropped)
- Making heart cells suited to the purpose: “2004 Heart Wall” OpenStax College / CC BY 3.0 (cropped)
- Related lab (Katada Lab): “Blausen 0216 CerebrospinalSystem” BruceBlaus. When using this image in external sources it can be cited as: Blausen.com staff (2014). "Medical gallery of Blausen Medical 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN . / CC BY 3.0 (cropped)
- Related lab (Sakurai Lab): “Skeletal muscle1-es” The original uploader was Jeremykemp at English Wikipedia. / CC BY 4.0 (cropped)
- Related lab (Kaneko Lab): “Human Natural Killer Cell ( )” NIAID / CC BY 2.0 (cropped)
- Related lab (Ikeya Lab): “Migration of Neural Crest Cells (v2)” MWatson12 / CC BY-SA 4.0 (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.