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927 labs · 0 student voices
Masayoshi Arai, Professor
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The Natural Product Drug Discovery Lab searches for compounds that could become the basis of drugs from marine organisms such as sponges and from marine-derived microorganisms. The lab investigates how the compounds it finds act in the body, and also aims to develop them into drug candidate compounds through chemical synthesis. The lab is divided into an exploration group and a synthesis group, and pursues drug discovery research from the perspectives of both chemistry and biology. Students join one of the two groups according to their interests and conduct research there.
Takumi Ueda, Professor
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The Quantitative Biophysical Chemistry Lab studies the dynamic 3D structures of drug-target proteins that are directly linked to their activity. By integrating these findings with insights from methods in other fields, the lab aims to understand life phenomena as a whole and to accelerate drug discovery. The lab uses methods such as NMR spectroscopy, X-ray crystallography, and cryo-electron microscopy. The lab is a division of the Graduate School of Pharmaceutical Sciences at The University of Osaka, and was previously named the Polymer Chemistry division.
Yoshinari Sawama, Professor
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The Functional Molecule Manufacturing Chemistry Lab builds on organic synthetic chemistry to research drug discovery using deuterium. The lab is pioneering a unique field, "deuterium science and deuterium drug discovery," which combines diversification through molecular structure with functionalization and refinement through deuterium. The lab also develops a wide range of catalytic organic synthesis methods, and is interested in developing green reactions that place no burden on the environment. The lab's website also introduces it under the name "Sawama Lab."
Hiroyuki Mizuguchi, Professor
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The Molecular Biology Lab (Life Pharmaceutical Sciences Area) develops technologies for introducing genes into cells to control their function, and conducts molecular biology research using those technologies. The lab also creates hepatocytes and intestinal epithelial cells from stem cells such as human iPS cells, and uses them in drug discovery research. The lab's website also introduces it under the name "Mizuguchi Lab."
Tatsuya Saitoh, Professor
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The Biological Response Regulation Lab (Prof. Saitoh's lab) studies the immune response, the biological response induced against foreign substances. While the immune response protects the body, when it is mistakenly directed against the body's own components or nutrients, it leads to autoimmune diseases and lifestyle-related diseases. The lab focuses in particular on innate immunity, investigating the immune mechanisms that prevent infections and cancer as well as the aberrant immune responses involved in the onset of disease. The lab also aims to develop therapeutic drugs that control the immune response.
Soichiro Fukada, Professor
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The Regenerative Adaptation Lab studies the regenerative and hypertrophic capacities of skeletal muscle at the molecular level, aiming for discoveries that form the foundation for developing treatments for muscle diseases. The lab investigates how muscle satellite cells, the stem cells of skeletal muscle, are kept in a quiescent state, and how muscle hypertrophy and muscle regeneration occur. In addition to muscle diseases such as muscular dystrophy, the lab is interested in sarcopenia and cancer cachexia, where muscle atrophy is a problem.
Yasuo Tsutsumi, Professor
0 student voices
The Toxicology Lab carries out education and research on predicting, evaluating, and ensuring the safety of pharmaceuticals, cosmetics, food, and newly developed chemical substances. For chemical substances including nanomaterials, the lab evaluates actual exposure and kinetics and assesses hazards, and also develops fundamental technologies that help ensure safety. Using methods such as genetic engineering, protein and antibody engineering, and omics analysis, the lab also works on investigating how toxicity arises and on developing detoxification methods (treatments and therapeutic drugs). Recently, the lab has been focusing on safety research on micro- and nanoplastics.
Hitoshi Hashimoto, Professor
0 student voices
The Neuropharmacology Lab is in the Medical and Public Health Pharmaceutical Sciences area of the Graduate School of Pharmaceutical Sciences. In Professor Hitoshi Hashimoto's entry in the researcher directory, the listed fields of specialty are medical pharmaceutical sciences, "pharmaceutical hygiene and biochemistry," and pharmacology. The listed research keywords are Comprehensive Brain Science Network, psychiatric disorders, schizophrenia, genetically modified mice, receptors, and PACAP. Its papers include a study that examined the antidepressant-like effects of a drug that inhibits PACAP receptors in a mouse model of chronic stress.
Yasushi Fujio, Professor
0 student voices
The Clinical Drug Efficacy Analysis Lab conducts research centered on cardiovascular disease, aiming to clarify how diseases develop and to establish new medical care. Professor Fujio regards clarifying the mechanisms by which diseases develop and establishing new medical care as the mission of clinical work at a university. The lab's basic philosophy is "bringing the breath of clinical practice into pharmaceutical sciences." In addition to cardiovascular disease, the lab also studies kidney disease.
Kenji Ikeda, Professor
0 student voices
The Medical Pharmacy Lab mainly conducts research to resolve questions and problems found in clinical practice from a pharmaceutical perspective. In collaboration with hospitals and pharmacies, the lab conducts clinical studies targeting both specific groups and large populations. By providing scientific evidence, the lab promotes the appropriate use of medicines and works on research that contributes to the safety and reassurance of medical care. Aiming for world-class clinical pharmacy, the lab seeks to establish clinical pharmacy that supports better medical care.
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