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Toxicology Lab (Medical and Hygienic Pharmaceutical Sciences)
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A toxicology lab that considers the safety of pharmaceuticals, food, and chemical substances in the environment.
AboutAbout the lab
Establishing a safe and secure healthy environment.
The Toxicology Lab carries out education and research on predicting, evaluating, and ensuring the safety of pharmaceuticals, cosmetics, food, and newly developed chemical substances.
For chemical substances including nanomaterials, the lab evaluates actual exposure and kinetics and assesses hazards, and also develops fundamental technologies that help ensure safety.
Using methods such as genetic engineering, protein and antibody engineering, and omics analysis, the lab also works on investigating how toxicity arises and on developing detoxification methods (treatments and therapeutic drugs).
Recently, the lab has been focusing on safety research on micro- and nanoplastics.
Key terms
- Microplastics
- Plastic particles of 5 mm or smaller found in the environment.
- Nanoplastics
- Plastic particles of 1 μm or smaller, smaller than microplastics.
- Hazard
- One of the elements when risk is expressed as "hazard × actual exposure and kinetics."
NewsLab news
A student received the Student Poster Presentation Award at the 53rd Annual Meeting of the Japanese Society of Toxicology
Research results accepted for publication in Biological and Pharmaceutical Bulletin
A student received the Excellent Presentation Award at the 146th Annual Meeting of the Pharmaceutical Society of Japan
Research results accepted for publication in Microplastics
Research results accepted for publication in RSC Advances
ResearchResearch themes
From the standpoint of pharmaceutical sciences, the Toxicology Lab considers the safety of pharmaceuticals, cosmetics, food, and the environment, aiming to establish a safe and secure healthy environment. It conducts research on the safety evaluation of chemical substances including nanomaterials, and develops fundamental technologies that help ensure safety.
*Illustrative imageReproductive and developmental toxicity and Nano-Safety Science
Research on Nano-Safety Science, focusing on reproductive and developmental toxicity, among other areas.
*Illustrative imageAnalysis and control of nanomaterial kinetics
Research on Nano-Safety Design, the optimal design of nanomaterials, concerning the analysis of their kinetics and its control.
*Illustrative imageMolecular pathology of cancer and other diseases, and drug discovery
Research that develops fundamental technologies for elucidating the molecular pathology of malignant tumors and other diseases, and extends them to drug discovery.
*Illustrative imageToxicity evaluation of microplastics
The lab investigates the genotoxicity, carcinogenicity, and immunotoxicity of microplastics and nanoplastics, aiming to develop detoxification methods. It prepares reference materials that reflect the complex forms in which they exist in the environment, and carries out integrated safety evaluation through analysis of their kinetics and hazards.
MembersFaculty
The lab's members are faculty, Visiting Professors, Visiting Associate Professors, visiting faculty and visiting researchers, administrative assistants, doctoral and undergraduate students, and research students.As of 2026
- ProfessorYasuo Tsutsumi
- Associate ProfessorKazuma Higashisaka
- Assistant ProfessorYuya Haga
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Toxicology Lab” Majordoc / CC BY-SA 4.0 (cropped)
- Reproductive and developmental toxicity and Nano-Safety Science: “Platinum nanoparticles” PieroSpeleo / CC BY-SA 4.0 (cropped)
- Analysis and control of nanomaterial kinetics: “Gold and silver nanoparticles in labelled Petri dishes” Drkirstyross / CC BY-SA 4.0 (cropped)
- Molecular pathology of cancer and other diseases, and drug discovery: “Breast cancer cell (2)” Unknown photographer / Public domain (cropped)
- Toxicity evaluation of microplastics: “Galinhos Beach, Galinhos (Rio Grande do Norte, Brazil, October 2023)” Malafaia2407 / CC BY 4.0 (cropped)
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