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Faculties at The University of Osaka ›
Satoshi Imazato, Professor (Concurrent)
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The lab studies the development and practical application of new materials for dentistry, and evaluates how well they work. It develops materials that act on living tissue according to changes in the oral environment and the stage of healing. It also works on materials that can suppress infection and promote tissue regeneration, as well as restorative and preventive materials with antibacterial properties. Using a bioreactor the lab built itself, it evaluates how well various dental materials suppress biofilm.
Kazuhiko Nakano, Professor (Concurrent)
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The lab studies the correlation between the oral environment and systemic condition, focusing on diseases influenced by periodontopathic and cariogenic bacteria. It analyzes patients' oral environment and systemic condition on a large scale and over a long period. Based on the results, it examines the effects of oral bacteria on systemic diseases from both basic and clinical perspectives. It also aims to spread awareness of how important it is to improve the oral environment in controlling systemic diseases.
Hironori Hojo, Professor
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The lab leads research and education on bioinformatics at the Graduate School of Dentistry. Under the bioinformatics platform initiative of the Strategic Council for Medical, Dental, Pharmaceutical and Life Sciences, it advances related research in an integrated way. It also collaborates with the Graduate School of Medicine, the Graduate School of Pharmaceutical Sciences, the Graduate School of Frontier Biosciences, the Research Institute for Microbial Diseases, and related departments at Osaka University. It also accepts consultations on research design using bioinformatics, and data analysis as joint research.
Yoshifumi Takahata, Associate Professor
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The Genome Editing Technology Development Unit views the genome as a "dynamic program" that changes over time, and studies how to control gene function from the outside. The unit investigates how the circadian clock affects the function of joints and bones, and aims for "time-targeted drug discovery", which intervenes at the optimal time in line with biological rhythms. The unit also develops technologies for creating its own research materials, such as mice and cell lines made with CRISPR/Cas9. The unit also supports researchers who use genome editing, for example by taking commissions to generate genetically modified mice and by holding seminars that include hands-on training.
Satoshi Yamaguchi, Professor
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The AI Research Unit widely applies cutting-edge technologies, including generative AI, to research in dentistry and oral science. Against the background of advances in AI technology known as deep learning, AI is increasingly being introduced in dental care for diagnostic support, image analysis, and optimization of treatment planning. The unit was established in April 2024 directly under the Graduate School of Dentistry, Osaka University. The unit also takes consultations on applying AI to research projects from faculty members, clinical staff, graduate students, and others in the departments of the school.
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