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Susumu Tanaka, Professor
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The Oral and Maxillofacial Surgery Lab conducts basic and clinical research centered on congenital anomalies such as cleft lip and palate, and on jaw deformities. Research in this lab also includes translational research aimed at clarifying disease mechanisms and developing new treatments. For oral cancer as well, the lab works with other institutions on developing diagnostic support systems aimed at early detection and early treatment, and on clarifying the mechanisms of carcinogenesis and metastasis. With the goal of training academic surgeons in the maxillofacial and oral region, the lab is also involved in undergraduate education, graduate education, and postgraduate clinical training.

Narikazu Uzawa, Professor
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The Oral and Maxillofacial Oncologic Surgery Lab is in charge of oral and maxillofacial surgery, which clarifies the causes of diseases of the jaw and oral cavity and links that knowledge to treatment. The lab carries out clinical care, education, and research on diseases such as congenital anomalies, jaw deformities, trauma, inflammation, tumors, and mucosal diseases. In the graduate school, the lab teaches Oral and Maxillofacial Oncology as the main subject and Advanced Oral and Maxillofacial Surgery as the secondary subject, making tumors a priority area for both clinical work and research. Its research addresses the mechanisms of lymph node metastasis in oral cancer, new molecular targeted therapies, and more.

Syumei Murakami, Professor
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The Dental Radiology Lab studies radiation therapy for oral cancer and head and neck cancer, and diagnostic imaging using CT and MRI. The oral cavity, and the tongue in particular, is involved in many functions such as mastication, swallowing, speech, and taste, so radiation therapy that can preserve function is often the first-choice treatment for cancer. The lab is equipped with a linac, the only external beam radiotherapy unit at the Dental Hospital affiliated with the Faculty of Dentistry, and uses it to treat patients with oral cancer and head and neck cancer. In diagnostic imaging, MRI and CT are used to comprehensively diagnose not only hard tissues such as teeth and jawbones but also soft tissues such as muscles, blood vessels, and mucosa.

Chiho Kudo, Professor
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Dental anesthesiology, the field this lab covers, centers on general anesthesia and applies its knowledge and techniques to patient management during dental care. The lab explains that administering general anesthesia is, in essence, the regulation of the body's physiological responses. People who are extremely afraid of dental treatment can be given sedatives so that they can receive treatment comfortably. Even people with severe heart disease, for whom dental treatment is considered risky, can be treated safely while their cardiac function is evaluated on monitors.

Kazuhiko Nakano, Professor
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The lab conducts basic and clinical research on dental caries and periodontal disease, which are among the dental diseases that occur from infancy through adolescence. The lab is responsible for pediatric dentistry lectures and practical training for undergraduate and graduate students, and also provides dental treatment for child patients at the pediatric dentistry clinic of the Dental Hospital affiliated with the Faculty of Dentistry. For Streptococcus mutans, a bacterium that causes dental caries, the lab examines how its surface structures relate to virulence. The lab analyzes how bacteria in the mouth relate to systemic diseases, using samples such as those removed during cardiovascular surgery.

Takashi Yamashiro, Professor
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The lab studies the growth and development of the teeth and face, jaw movement, and related topics in the field of orthodontics. Orthodontics is a field that seeks the factors that create the optimal natural-teeth occlusal relationship in order to achieve an attractive mouth and stable occlusal function. Research areas in orthodontics range from the perception of facial shape and expression, to the morphogenesis of bone and teeth, the control of jaw movement, and pain control. The lab also works to train leading professionals who can succeed in Japan and abroad and carry orthodontic care forward in the 21st century.

Shigehisa Akiyama, Associate Professor
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The Special Needs Dentistry Lab conducts research on providing dental care and oral health services to people with physical or mental illnesses or disabilities (people with special needs). The lab investigates the dental characteristics of people with disabilities and the mechanisms of their oral diseases. It works on a wide range of topics, from treatment and prevention methods and support for dental visits to building systems for delivering care. The lab also develops information accessibility support for people with visual or hearing impairments, and tools that help people with developmental disabilities receive dental care. Developing educational methods that help dental students deepen their learning about dentistry for people with disabilities is also one of the lab's research themes.

Takayoshi Sakai, Professor
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The Oral and Maxillofacial Functional Therapeutics Lab addresses disorders of the oral functions of speaking, eating, and breathing through both treatment and clinical education and research. Its targets include speech disorders, dysphagia (eating and swallowing disorders), and sleep apnea, as well as xerostomia (dry mouth) and malnutrition caused by oral dysfunction. Its research includes developing endoscopic evaluation methods, analyzing swallowing dynamics with videofluoroscopic swallowing studies, and analyzing the mechanisms of salivary gland regeneration.

Takeshi Noda, Professor
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The Oral Cell Biology Lab conducts research that opens up the field of oral medical science from the perspective of cell biology, including autophagy. The lab's scope extends from elucidating fundamental principles of life to clinical applications. The lab studies how cells sense the presence or absence of nutrients, and the mechanism of microautophagy, one type of autophagy. As a research support branch, the lab is also responsible for maintaining shared equipment and animal facilities, supporting research across the entire Graduate School of Dentistry.

Satoshi Imazato, Professor (Concurrent)
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The lab studies the development and practical application of new materials for dentistry, and evaluates how well they work. It develops materials that act on living tissue according to changes in the oral environment and the stage of healing. It also works on materials that can suppress infection and promote tissue regeneration, as well as restorative and preventive materials with antibacterial properties. Using a bioreactor the lab built itself, it evaluates how well various dental materials suppress biofilm.
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