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Pediatric Dentistry Lab
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A pediatric dentistry lab that investigates children's dental caries, periodontal disease, and oral bacteria from both basic and clinical perspectives.
AboutAbout the lab
Studying children's oral diseases through basic and clinical research
The lab conducts basic and clinical research on dental caries and periodontal disease, which are among the dental diseases that occur from infancy through adolescence.
The lab is responsible for pediatric dentistry lectures and practical training for undergraduate and graduate students, and also provides dental treatment for child patients at the pediatric dentistry clinic of the Dental Hospital affiliated with the Faculty of Dentistry.
For Streptococcus mutans, a bacterium that causes dental caries, the lab examines how its surface structures relate to virulence.
The lab analyzes how bacteria in the mouth relate to systemic diseases, using samples such as those removed during cardiovascular surgery.
Key terms
- Dental caries
- A dental disease commonly known as tooth decay (cavities).
- Streptococcus mutans
- One of the bacteria that cause dental caries (cariogenic bacteria).
- Infective endocarditis
- A disease in which infection occurs in the inner lining of the heart and nearby tissue. Antibiotics are sometimes given before dental treatment as a preventive measure.
NewsLab news
Developed a model mouse that reproduces the dental symptoms of hypophosphatasia (published in JBMR Plus)
A student received the Encouragement Award for Outstanding Graduate Student Presentation Overseas from the Osaka University Dental Society
An assistant professor received the Encouragement Award from the Japanese Society of Pediatric Dentistry
A lab member received the Excellent Presentation Award, among other awards, at the Kinki Regional Meeting of the Japanese Society of Pediatric Dentistry
An assistant professor received the Outstanding Research Encouragement Award from the Osaka University Dental Society
ResearchResearch themes
The lab conducts research from both basic and clinical perspectives, focusing on dental caries and periodontal disease, which are dental diseases that occur from infancy through adolescence. It also investigates how bacteria in the mouth are linked to systemic diseases.
*Illustrative imageBasic and clinical research on dental caries and periodontal disease
Using molecular biology methods and experimental animal models, the lab examines how the surface structures of Streptococcus mutans relate to virulence. For periodontal disease, it analyzes bacterial colonization and the distribution of bacterial species in mothers and children over time, aiming to develop methods to predict who is likely to develop the disease.
*Illustrative imageOral bacteria and systemic disease
The lab isolates oral streptococci from the blood, valve tissue, and dental plaque of patients with infective endocarditis and analyzes their characteristics, and it also examines samples removed during cardiovascular surgery. It further analyzes effects on the cerebrovascular system, aiming to establish a simple method to identify people who carry strains likely to cause disease.
MembersFaculty
The members of the Pediatric Dentistry Lab consist of faculty, staff dentists, graduate students, residents, Clinical Professors and Clinical Lecturers, graduate students who are working professionals, registered trainee dentists, and project administrative staff.As of 2026
- ProfessorKazuhiko Nakano
- Associate ProfessorRena Okawa
- Project Associate ProfessorJinthana Lapirattanakul
- Assistant ProfessorYuto Suehiro
- Assistant ProfessorMasatoshi Otsugu
- Assistant ProfessorTamami Kadota
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Streptococcus mutans Gram” Y tambe / CC BY-SA 3.0 (cropped)
- Basic and clinical research on dental caries and periodontal disease: “Mutans Streptococci colonies on Mitis Salivarius Agar” Ronit611 / CC BY-SA 3.0 (cropped)
- Oral bacteria and systemic disease: “Histopathology of a heart valve with dystrophic calcification” Mikael Häggström, M.D. Author info - Reusing images- Conflicts of interest: None Mikael Häggström, M.D.Consent note: Consent from the patient or patient's relatives is regarded as redundant, because of absence of identifiable features (List of HIPAA identifiers) in the media and case information (See also HIPAA case reports guidance). / CC0 (cropped)
- Related lab (Oral and Maxillofacial Surgery Lab): “Dental instruments by Roboz Tech Surgical” RobozTech / CC BY-SA 4.0 (cropped)
- Related lab (Periodontology Lab): “Healthy gingiva” Mohamed Hamze / Public domain (cropped)
- Related lab (Comprehensive Dentistry Lab): “Hospital Dental Engine” Ptrump16 / CC BY-SA 4.0 (cropped)
- Related lab (Oral and Maxillofacial Oncologic Surgery Lab): “Circumcision instruments on green cloth in tray - right” Dan Bollinger / CC BY-SA 4.0 (cropped)
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