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927 labs · 0 student voices

Takeshi Bamba, Professor
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The Systems Metabolism Lab (Bamba Lab) conducts research on technologies for analyzing the metabolome, the totality of metabolites, and on the field of study known as metabolomics. Using chromatography and mass spectrometry, the lab develops analytical methods that measure intracellular metabolic information with high sensitivity and quantitative accuracy. With the methods it develops, the lab investigates the relationship between disease and metabolism from basic to applied research, and also aims at integrated analysis with other omics. Through thorough on-the-job training, the lab aims to develop professional analytical chemists who can be active around the world.

Eiichi Morii, Professor
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The Disease Pathology Lab works on both pathological diagnosis of specimens at the University Hospital and pathology research. For the diseases encountered in daily diagnosis, the lab imagines the mechanisms behind what can be seen and conducts research to test them. The lab focuses on tumor heterogeneity: tumor cells that should be a single clone have different properties from cell to cell. The lab also works on methods for observing pathological tissue with new technologies.

Daichi Inoue, Professor
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The Cancer Pathology Lab investigates the mechanisms of blood cancers such as myelodysplastic syndromes and acute myeloid leukemia, and extends its research to solid cancers in general. The lab seeks to understand the differences between normal stem cells and cancer stem cells, and aims at therapeutic applications that build on the vulnerabilities of cancer revealed by those differences. From the perspectives of genomic mutations, post-transcriptional regulation, chromatin regulation, metabolic reprogramming, and cell death, the lab tackles cancer from both basic and clinical sides.

Hiroshi Hibino, Professor
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The Integrative Pharmacology Lab focuses mainly on the inner ear and pharmacokinetics, studying in detail how the body is built and how it works, and how diseases arise. The lab draws on techniques and knowledge from other fields, including engineering, and uses measurement technologies that it has developed and optimized on its own through medical-engineering collaboration. Using animal models, the lab is committed to measuring local sites in vivo, and combines this with histological, biochemical, and molecular biological analyses. The lab has also begun research on hearing, the brain, and brain diseases.

Kazuhiro Suzuki, Professor
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The Environmental Response Pharmacology Lab aims to clarify, at the cellular and molecular level, how the nervous system regulates immune responses. Using mice, the lab investigates how noradrenaline released from sympathetic nerves affects the movement of lymphocytes. Using molecules involved in lymphocyte migration as clues, the lab is also developing new treatments for autoimmune diseases. The lab's website introduces it under the name "Immune Response Dynamics Lab."

Ryo Kawasaki, Professor
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The Public Health Lab conducts epidemiological research on a wide range of diseases through cohort studies, studies using administrative health data, and clinical database studies. The lab also works on social epidemiology, policy evaluation, and digital health research. In collaboration with universities and research institutions in Japan and abroad, the lab runs various cohort studies and analyzes their data. The lab belongs to the Department of Social Medicine at the Graduate School of Medicine, The University of Osaka.

Hiroshi Matsumoto, Professor
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The lab works in forensic medicine, the only field of medicine that deals with the death of an individual, and centers its research on cause-of-death investigation, starting from the question of why people die. The lab clarifies the mechanisms of sudden deaths that never reach clinical care, deaths caused by the environment such as heatstroke and freezing, and alcohol-related deaths, and studies how to prevent and treat them. Autopsy is not the only way to investigate a cause of death. The lab also uses biochemical tests during autopsy, analysis of drugs and poisons with mass spectrometry instruments, and whole-exome sequencing with next-generation sequencers. Medical students can choose this lab through the Year 3 basic lab placement or the Year 5 lab placement.

Eiryo Kawakami, Professor
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The lab uses artificial intelligence and data science to tackle problems in medicine and healthcare. It aims to draw out new ways of seeing disease by linking diverse medical data, including electronic health records, health checkups, medical images, genetic and omics data, and wearable data. It pursues predicting disease onset and severity, understanding differences between patients, and understanding disease mechanisms at the molecular level as one continuous flow. The lab aims to use AI not merely as a tool but as a foundational technology that changes how medicine and medical research are done.

Kiyoshi Takeda, Professor
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The lab researches how to make it possible to control intractable immune diseases that current medical technology cannot cure. It focuses especially on inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis, studying the intestinal immune system, gut environmental factors such as gut bacteria and dietary components, and the function of the epithelial layer that separates the two. Inflammatory bowel disease is thought to develop when abnormalities of the gut environment overlap with abnormalities of the immune system. The lab welcomes students who take an active rather than passive approach and are passionate about immunology research.

Masaru Ishii, Professor
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The Immune Cell Biology Lab studies how cells of the immune and blood systems move within the body and how they link the functions of organs and tissues. As cells of the immune and blood systems circulate throughout the body, the functional connections among organs and tissues are maintained. When these connections break down, various diseases arise, including lifestyle-related diseases and cancer. The lab observes the inside of bone in living animals using two-photon excitation microscopy, and examines immune cells and other cells by in vivo imaging. The lab is a core department of both the Graduate School of Medicine and the Graduate School of Frontier Biosciences, and can accept graduate students from either.
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