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Systems Metabolism Lab
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The lab refines analytical technologies for comprehensively measuring metabolites.
AboutAbout the lab
Taking on the challenge of understanding living systems through metabolic analysis technology.
The Systems Metabolism Lab (Bamba Lab) conducts research on technologies for analyzing the metabolome, the totality of metabolites, and on the field of study known as metabolomics.
Using chromatography and mass spectrometry, the lab develops analytical methods that measure intracellular metabolic information with high sensitivity and quantitative accuracy.
With the methods it develops, the lab investigates the relationship between disease and metabolism from basic to applied research, and also aims at integrated analysis with other omics.
Through thorough on-the-job training, the lab aims to develop professional analytical chemists who can be active around the world.
Key terms
- Metabolome
- The totality of metabolites. It can be used as an indicator of the state of life activity.
- Metabolomics
- The technologies and field of study for analyzing the metabolome.
NewsLab news
Paper from a joint study with Kyushu University accepted by The Journal of Clinical Endocrinology & Metabolism
The Systems Metabolism field launched
ResearchResearch themes
Enzyme proteins produced from genome information synthesize metabolites, and the totality of these metabolites is the metabolome. The lab works on developing technologies for analyzing the metabolome and on applied research into the relationship between disease and metabolism.
*Illustrative imageDevelopment of analytical methods for the hydrophilic metabolome
The lab develops analytical methods for comprehensively measuring the hydrophilic metabolome.
*Illustrative imageHydrophilic metabolome measurement method
The lab works with a measurement method called unified-HILIC/AEX/MS. Metabolites include components taken in from food and components biosynthesized in the body from them.
*Illustrative imageDevelopment of quantitative lipidome analysis methods
The lab develops methods for quantitatively analyzing lipids. Lipids are one of the three major nutrients, along with carbohydrates and proteins, and serve as major components of biological membranes and as an energy source, among other roles.
MembersFaculty
The members of the Systems Metabolism Lab consist of faculty, project faculty, academic researchers, PhD students, special research students, technical staff, and administrative staff.As of 2026
- ProfessorTakeshi Bamba
- Associate ProfessorSho Tabata
- Assistant ProfessorKeisuke Nakata
- Assistant ProfessorAtsuki Matsubara
- Project Associate ProfessorTakuya Yamane
- Project Assistant ProfessorHitomi Shukuri
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Mass Spectrometry Laboratory ( )” IAEA Imagebank / CC BY-SA 2.0 (cropped)
- Development of analytical methods for the hydrophilic metabolome: “Mass Spectrometry Machine (NIH BioArt 286)” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
- Hydrophilic metabolome measurement method: “Whole body by Mass Spectrometry Imaging” Imabiotech / CC BY-SA 4.0 (cropped)
- Development of quantitative lipidome analysis methods: “The surface of highly curved lipid bilayer” Semen Yesylevskyy / CC BY 4.0 (cropped)
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