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927 labs · 0 student voices

Madoka Suzuki, Independent Associate Professor
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The Protein Physical Biology Lab studies phenomena related to heat production in living organisms, aiming to understand them at the spatial scale of the cell. The lab develops methods for local heat stimulation and for measuring temperature with an optical microscope. It applies these methods to experimental systems at various spatial scales, from biomolecules to whole organisms. Together with collaborators in Japan and abroad, the lab pursues both curiosity-driven themes in search of fundamental truths and disease-related themes.

Nobuyasu Koga, Professor
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The Protein Design Lab designs proteins on computers based on physical chemistry and data science, and studies how their structures form and the principles by which their functions emerge. The lab believes that natural proteins are finished products that nature has spent billions of years creating, and that analyzing them alone makes it difficult to clarify the mechanisms by which they work. The lab uses biochemical experiments to examine how the designed proteins actually behave, and uses the results to develop protein design technology. The lab is located in the Advanced Protein Data Science Research Center (ASPiRE), part of the Institute for Protein Research at Osaka University, and the site also introduces it under the name "Koga Lab."

Atsuko Yamashita, Professor
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The Biomolecular Recognition Lab aims to understand how organisms perceive the external world, based on the structure and function of protein molecules. The lab's website reports that results of joint research on taste receptors have been published in multiple academic journals. Prof. Yamashita took part in joint research on sweet taste receptors with NARO (National Agriculture and Food Research Organization) and others, contributing from the perspective of receptor structure. The lab opened in December 2024, and Assistant Professor Itoigawa joined in April 2025.

Makoto Sato, Professor
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The Neural Function and Morphology Lab studies how the neocortex, which exists only in higher animals, is formed. Psychiatric disorders such as developmental disorders and schizophrenia are also thought to have their causes or predisposing factors in minor malformations that occur when the brain is formed. Using mice, the lab studies the migration of neurons and the formation of circuits of nerve fibers extending from the cerebral cortex. Members from different undergraduate faculties, such as medicine, science, and agriculture, work together on research.

Akihiro Harada, Professor
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The Cell Biology Lab aims to elucidate the mechanisms of polarized transport, which is important for protein secretion in cells and for the formation and maintenance of cell polarity. The lab investigates the structure and function of the Golgi apparatus using super-resolution microscopy and electron microscopy. The lab also generates knockout mice lacking specific genes and analyzes how transport changes in cells and in whole organisms.

Toshihide Yamashita, Professor
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The Molecular Neuroscience Lab conducts basic research and developmental research that contribute to overcoming the lasting impairments of the nervous system caused by cerebrovascular disease and by trauma to the brain and spinal cord. In the brain and spinal cord, neurons work by forming networks, and when these networks are damaged, recovery is extremely rare. Believing that central nervous system disorders can be treated if the lost networks can be repaired, the lab aims to establish new neural regeneration therapies. At the same time, the lab seeks to study the dynamics of the process by which neural circuits are repaired through an integrated approach.

Shigeru Kitazawa, Professor
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The Brain Physiology Lab studies a wide range of brain functions, including perception, movement, cognition, and communication. Under the motto of "brain science that you can experience," the lab works on topics such as the mechanism by which the world does not appear to move even when the eyes move, the sense of mental time, and the mechanisms of motor learning. In addition to behavioral experiments and brain activity measurements in humans, the lab also examines brain activity in monkeys. On the lab's website, it is introduced under the name "Dynamic Brain Network Lab."

Yoshifumi Okochi, Associate Professor
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The Integrative Physiology Lab studies ion channels, the proteins responsible for electrical signals in living organisms, from their microscopic structure and function to their physiological roles in the whole organism. The lab takes approaches including molecular biology, knockout mice, electrophysiology, imaging, and structural biology. The lab discovered two proteins with voltage sensors, VSP and VSOP/Hv1, and is investigating how they work and what roles they play in the body.

Seiji Takashima, Professor
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The Medical Biochemistry Lab studies how life processes work and how diseases arise, using the functions of proteins as clues. The lab prioritizes exploratory research, which first discovers new biological phenomena at the molecular level, and connects it to its own systems for analyzing physiological function. The ultimate goal is to understand disease pathology and develop disease treatments. The main target diseases are cardiovascular diseases such as heart failure and ischemic heart disease. The lab believes that collaboration and cooperation with researchers and institutions across fields, not only within cardiovascular research, is essential.

Noriyuki Tsumaki, Professor
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The Tissue Biochemistry Lab studies how cartilage, the basis of the skeleton, forms, and the diseases that affect cartilage. Cartilage includes articular cartilage and growth plate cartilage. Abnormalities of articular cartilage cause joint movement disorders, and abnormalities of growth plate cartilage cause skeletal growth disorders. Using techniques of biochemistry, molecular biology, and histology, the lab investigates the mechanisms that regulate cartilage formation and differentiation, and attempts to elucidate the pathology of cartilage diseases. The lab also works on new regenerative therapy for cartilage using iPS cell technology, as well as on drug discovery.
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