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927 labs · 0 student voices
Ken'ya Furuta, Visiting Associate Professor
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The Biomolecular Machine Design Lab studies how biological molecular motors such as kinesin and dynein move reliably in one direction in a nanoscale world dominated by thermal fluctuations. Beyond examining existing molecular motors, the lab is trying to establish a “create to understand” approach: prototyping new molecular motors from simple components and understanding them through their behavior. It also focuses on the connection between parts and the whole as the hierarchy rises from molecules to organelles, cells, and individuals, and investigates collective properties in model systems using DNA nanostructures and other materials. The laboratory space is located in the Advanced ICT Research Institute (Kobe/Akashi) of the National Institute of Information and Communications Technology (NICT), and the lab operates as a team within NICT's Biophysics Project.
Li-Kun Phng, Visiting Associate Professor
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The lab studies how blood vessels are formed and maintained during development and afterward. Using zebrafish embryos, it examines how the shape and movement of endothelial cells are regulated, with methods such as high-resolution time-lapse imaging. It also focuses on how forces generated by blood flow affect endothelial cell behavior and blood vessel shape. The research is conducted at the RIKEN Kobe Campus, and the lab is introduced at Osaka University as a lab of the Department of Biological Sciences.
Hiroki Shibuya, Visiting Associate Professor
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The Life Inheritance Systems Lab studies the molecular basis of biological phenomena unique to germ cells. Even when an individual organism reaches the end of its life, a species can persist almost indefinitely, because germ cells refresh genetic information and pass it on accurately to the next generation. The lab focuses on meiosis, which halves the number of chromosomes, and on differentiation into sperm and eggs (gametes), and studies them using mice and nematodes. The lab's website presents it as the “Gametogenesis Research Team” of the RIKEN Center for Biosystems Dynamics Research.
Atsushi Tamii, Professor
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The Tamii Lab (Fundamental Nuclear Physics Group) studies the properties of nuclear matter made of protons and neutrons, aiming to discover new phenomena and solve mysteries related to how the universe came to be. Using the quantum beams and the “Grand Raiden” spectrometer at the Research Center for Nuclear Physics, Osaka University, the lab carries out joint research with leading research groups around the world. The research covers the electric polarizability of atomic nuclei, the equation of state of neutron stars, and photodisintegration reactions of ultra-high-energy cosmic rays. The lab also develops the detectors and data acquisition systems used in its experiments. On the lab's website, it is also introduced under the name “Tamii Lab.”
Hajime Yoshino, Professor
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The Yoshino Lab studies a variety of interdisciplinary themes using the methods of statistical physics and computational physics. Its current main theme is “the physics of learning and design,” together with the “physics of random systems” that underlies it. The lab covers the statistical mechanics of learning in deep neural networks, and the physics of random systems ranging from solid-state physics, soft matter, and active matter to information statistical mechanics. The Yoshino Lab is the Large-Scale Computational Science Division of the D3 Center at Osaka University, and its graduate students belong to the Department of Physics, Graduate School of Science.
Masato Nakai, Associate Professor
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The Organelle Biology Lab studies the functions and biosynthesis of proteins that work in chloroplasts and other organelles, the subcellular compartments characteristic of plants and algae. The lab's main theme is how chloroplasts are formed and how they support the life activities of plants. Together with many research groups in Japan and abroad, the lab approaches this question from diverse angles, including plant molecular and cell biology, plant physiology, protein chemistry, and structural biology. On the lab's website, it is also introduced under the name "Nakai Lab."
Takahisa Furukawa, Professor
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The Molecular Developmental Biology Lab studies how the vertebrate central nervous system is built, focusing on the mechanisms of its development. Mainly using the retinal visual system as a model, the lab investigates the path by which genetic programs encoded in the genome generate neurons, shape neural circuits, and lead to the function of nerves in the body. The lab also tackles medical questions of how abnormalities at each level, from genes to physiological function, lead to human disease and how they can be resolved. Graduate students can join through the Graduate School of Science (Department of Biological Sciences), the Graduate School of Frontier Biosciences, or the Graduate School of Medicine.
Akira Shinohara, Professor
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The Genome-Chromosome Function Lab studies the mechanisms that generate the stability and diversity of genes, chromosomes, and DNA. Focusing on homologous recombination, an exchange reaction between DNA molecules, the lab examines the repair of DNA damage and the segregation of chromosomes in meiosis, the cell division that produces eggs and sperm. The lab believes this research will contribute to understanding cancer caused by genome instability, and miscarriage caused by aneuploidy in eggs and sperm. To clarify the molecular mechanisms of recombination and its functions in cells, the lab uses baker's yeast.
Shiroh Iwanaga, Professor
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The Parasitology Lab studies Plasmodium, the malaria parasite that causes malaria, one of the three major infectious diseases, from the standpoint of basic biology. Unlike viruses and bacteria, the malaria parasite is a eukaryote, like us. The lab aims to understand its survival strategy at the molecular level through the mechanisms of gene expression, and to find its weaknesses. Using next-generation sequencer analysis and CRISPR/Cas9, and moving between medicine and basic biology, the lab aims for results that contribute to malaria control. On the lab's website, it is introduced as the "Iwanaga Lab, Division of Molecular Protozoology" of the Research Institute for Microbial Diseases.
Tohru Ishitani, Professor
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The Biological Regulation Lab studies the mechanisms by which the body is formed, maintained, and ages, using imaging and model animals. One pillar of its research is "cell competition," which examines how abnormal cells arising in a cell population are detected by surrounding cells and eliminated. The other pillar is research on predicting and controlling human aging and lifespan using the killifish, an extremely short-lived fish with a lifespan of 3 to 6 months. On the lab's website, it is introduced under the name "Ishitani Lab."
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