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66 labs · 0 student voices
Faculties at The University of Osaka ›
Fumihiro Fujiki, Associate Professor, Endowed Chair
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The Cancer Vaccine Therapy Lab studies cancer vaccines that target WT1, a tumor antigen produced in large amounts in most types of human tumors. Cancer-specific immunotherapy is a field attracting attention as a treatment alongside surgery, radiation, and chemotherapy. The lab's distinguishing feature is that it can carry out everything from basic research to clinical research in the field of tumor immunotherapy. The lab is established as an endowed department of the Graduate School of Medicine.
Ryuichi Morishita, Professor, Endowed Chair
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The Clinical Gene Therapy Lab carries out research in several groups, including a dementia group and a cardiovascular group. The dementia group studies tau protein in Alzheimer's disease and develops methods for assessing cognitive function using eye gaze. The cardiovascular group targets heart failure, vascular diseases, aging, stem cells, and cancer, aiming to develop new therapeutic drugs and other treatments that are useful in clinical practice. The lab also has a health and developmental medicine group, an immunity, cerebrovascular, and neurology group, and a collaborative research group.
Hidetoshi Hamada, Associate Professor, Endowed Chair
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The Musculoskeletal Medical-Engineering Therapeutics Lab is an endowed chair that combines medical and engineering technologies to develop materials and surgical systems used in surgery for fractures and joint diseases. The lab develops devices that fix fractures, and aims to develop long-lasting next-generation artificial joints and computer-assisted surgery systems. Proximal femoral fractures and chronic hip joint diseases are considered to carry a high risk of leading to locomotive syndrome if they are not properly treated. Surgical treatment that relieves joint pain and quickly restores stability and mobility is considered to play an important role in extending healthy life expectancy.
Kotaro Saga, Associate Professor, Endowed Chair
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The Regeneration-Inducing Medicine Lab, an endowed chair, studies how tissue stem cells are maintained in the living body and how they are activated when tissue is damaged. The lab focuses on HMGB1, a protein released from necrotic tissue, which increases mesenchymal stem cells in the blood and promotes tissue regeneration. Based on findings from basic research, the lab is also developing an agent that increases mesenchymal stem cells in the blood. The lab's webpage says that people who are interested are welcome to join.
Yuya Fujishima, Associate Professor, Endowed Chair
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The Metabolism and Vascular Medicine Lab is an endowed chair that studies lifestyle-related diseases and arteriosclerosis broadly, from basic medicine to clinical medicine. Its research rests on the understanding that arteriosclerosis progresses on the basis of abnormalities such as those in blood glucose and blood pressure and ultimately leads to death, and that these abnormalities are mainly due to the accumulation of visceral fat. The lab discovered adiponectin as a molecule that directly links visceral fat and arteriosclerosis, and has studied its significance and function in humans. The lab proposed visceral fat syndrome and metabolic syndrome, and aims to clarify the mechanisms by which these conditions arise.
Susumu Sakimoto, Associate Professor, Endowed Chair
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The Applied Stem Cell Medicine Lab studies pluripotent stem cells such as iPS cells and ES cells, as well as mesenchymal stem cells and epithelial stem cells. The lab aims to clarify the mechanisms of stem cell differentiation and maintenance of the undifferentiated state, and, based on these findings, to develop new medical technologies for curing diseases. The lab carries out translational research, which develops basic research into practical medical technologies. Using methods from cell biology, regenerative medicine, molecular biology, and tissue engineering, the lab welcomes students and researchers from a wide range of fields, including medicine, engineering, pharmacy, agriculture, science, and veterinary medicine.
Junji Kozawa, Associate Professor, Endowed Chair
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The Diabetes Pathophysiology and Medical Care Lab is an endowed department of the Osaka University Graduate School of Medicine, and aims to provide appropriate diabetes care according to each patient's pathophysiology and comorbidities. Its main theme is how treatment should be carried out depending on age, serious coexisting diseases, and the pathophysiology of diabetes. The lab studies how to choose drugs for older patients, treatment of patients who also have cancer, delayed diagnosis and treatment interruption in lifestyle-related diseases, and factors that improve insulin resistance. Putting patients at the center, the lab sets out to share information on how best to manage diabetes for patients in a variety of situations, as a form of medical science for care.
Hironori Nakagami, Professor, Endowed Chair
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The Endowed Department of Health and Developmental Medicine focuses on putting research from a variety of fields to practical use, with the development of therapeutic vaccines as its main theme. Believing that vaccines may in the future become one treatment option for lifestyle-related diseases that require daily lifelong medication, the lab conducts research and development centered on peptide vaccines. Aiming for applied research that goes beyond basic research, the lab conducts joint research and development with various labs in Japan and actively promotes industry-academia collaboration. It began in April 2010 as an endowed department of the Osaka University United Graduate School of Child Development, and has been an endowed department of the Graduate School of Medicine since April 2015.
Michio Otsuki, Professor, Endowed Chair
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The lab studies what happens in the adipose tissue and adipocytes of people with obesity, aiming to uncover the mechanisms by which metabolic syndrome develops. Adipocytes store energy when there is a surplus and release it when there is a shortage, which keeps the body's condition stable. In modern Japan, however, increased calorie intake and lack of exercise cause surplus energy to keep flowing into adipocytes, which is described as leading to conditions such as diabetes and dyslipidemia. Centered on pathological analysis of obese adipose tissue and functional analysis of adipocytokines, the lab aims to overcome lifestyle-related diseases.
Takatoshi Maeno, Professor, Endowed Chair
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The Endowed Chair of Advanced Vision Medicine conducts clinical research that evaluates eye diseases and systemic diseases using ocular imaging devices and clinical samples. Using devices such as anterior segment optical coherence tomography, which captures cross-sectional images of the cornea, the lab has newly reported that systemic diseases are associated with characteristic changes in the cornea. In addition to imaging-based diagnosis of diseases such as keratoconus and Harada disease, the lab explores methods to diagnose infections, tumors, and inflammatory diseases using very small samples such as tears and intraocular fluid. The lab is an endowed chair of the Graduate School of Medicine at Osaka University.
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