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Health and Developmental Medicine Lab
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The lab aims to treat lifestyle-related diseases with vaccines.
AboutAbout the lab
Taking on the treatment of lifestyle-related diseases with vaccines
The Endowed Department of Health and Developmental Medicine focuses on putting research from a variety of fields to practical use, with the development of therapeutic vaccines as its main theme.
Believing that vaccines may in the future become one treatment option for lifestyle-related diseases that require daily lifelong medication, the lab conducts research and development centered on peptide vaccines.
Aiming for applied research that goes beyond basic research, the lab conducts joint research and development with various labs in Japan and actively promotes industry-academia collaboration.
It began in April 2010 as an endowed department of the Osaka University United Graduate School of Child Development, and has been an endowed department of the Graduate School of Medicine since April 2015.
Key terms
- Therapeutic vaccine
- A vaccine used not to prevent infectious diseases but to treat diseases such as lifestyle-related diseases and chronic inflammatory diseases
- Peptide vaccine
- A vaccine whose component is a peptide, a short molecule made of linked amino acids
- Epitope
- The part of a molecule, such as one from a pathogen, that the immune system recognizes as a marker
NewsLab news
Endowed Associate Professor Hiroki Hayashi receives the 2025 Society Award from the Japanese Society of Anti-Aging Medicine
Paper by Endowed Professor Hironori Nakagami accepted by Int Heart J
Endowed Associate Professor Hiroki Hayashi wins the Grand Prize at the 1st Sunny Health Rejuvenation Contribution Award
Review article by Endowed Professor Hironori Nakagami published in the book "Hajimeyo Kotsusoshosho Chiryoyaku: Erabikata to Tsukaikata" (Getting Started with Osteoporosis Drugs: How to Choose and Use Them)
ResearchResearch themes
In a super-aged society, more treatment options that take cost and efficiency into account are needed for diseases. The lab conducts research and development on therapeutic vaccines targeting lifestyle-related diseases and chronic inflammatory diseases, centered on peptide vaccines.
*Illustrative imageTherapeutic vaccines for lifestyle-related diseases and chronic inflammation
The lab conducts research and development, centered on peptide vaccines, for lifestyle-related diseases that require daily lifelong medication and for chronic inflammatory diseases treated continuously with antibody drugs. To reach practical use, the work is carried out through industry-academia collaboration.
*Illustrative imageDevelopment of novel epitope vaccines
The lab has built its own peptide vaccine system and is using the epitope analysis performed in its COVID-19 vaccine work to move better vaccines toward practical use. In the future, it aims for early therapeutic intervention in aging-related diseases, genetic diseases, and more.
MembersFaculty
The members of the Endowed Department of Health and Developmental Medicine consist of faculty, project researchers, part-time project researchers, graduate students, special research students, project administrative staff, temporary agency staff, and researchers from FunPep.As of 2026
- Professor, Endowed ChairHironori Nakagami
- Associate Professor, Endowed ChairHiroki Hayashi
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Japanese female scientist wearing plastic gloves holding syringe and vial, researching a coronavirus vaccine ( )” Japanexperterna.se from Japan / CC BY 2.0 (cropped)
- Therapeutic vaccines for lifestyle-related diseases and chronic inflammation: “Infanrix hexa vaccine” Whispyhistory / CC BY-SA 4.0 (cropped)
- Development of novel epitope vaccines: “Protein Structure Diagram of Fusion Peptide Epitope on HIV Spike ( )” NIAID / CC BY 2.0 (cropped)
- Related lab (Clinical Gene Therapy Lab): “AAV Gene Therapy” George Church / CC BY-SA 3.0 (cropped)
- Related lab (Lifestyle Medicine Lab): “Healthy meal planning with fresh fruits and vegetables in a bright kitchen setting” Shixart1985 / CC BY 2.0 (cropped)
- Related lab (Drug Discovery Neuroscience Lab): “Drug discovery cycle 2” Boghog / CC BY-SA 4.0 (cropped)
- Related lab (High-Precision Image-Guided Puncture Therapy Lab): “Interventional radiology” Elena Escalante Porrua / CC BY-SA 4.0 (cropped)
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