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Advanced Vision Medicine Lab
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An endowed chair for clinical research that uses state-of-the-art devices to examine diseases of the eye and the whole body.
AboutAbout the lab
Examining the eye with cutting-edge devices to explore disease diagnosis
The Endowed Chair of Advanced Vision Medicine conducts clinical research that evaluates eye diseases and systemic diseases using ocular imaging devices and clinical samples.
Using devices such as anterior segment optical coherence tomography, which captures cross-sectional images of the cornea, the lab has newly reported that systemic diseases are associated with characteristic changes in the cornea.
In addition to imaging-based diagnosis of diseases such as keratoconus and Harada disease, the lab explores methods to diagnose infections, tumors, and inflammatory diseases using very small samples such as tears and intraocular fluid.
The lab is an endowed chair of the Graduate School of Medicine at Osaka University.
Key terms
- Keratoconus
- A degenerative corneal disease in which part of the cornea bulges and becomes thinner. The mechanism of onset has not been clarified.
- Flare meter
- A device that uses a laser to measure, without damaging the body, proteins and other substances leaking from blood vessels in the eye. It is used to assess disease activity.
- Flow cytometry
- A test that analyzes cells contained in intraocular fluid. It is used to diagnose tumors and inflammatory diseases of the eye.
ResearchResearch themes
The human eye can now be evaluated from many angles with state-of-the-art imaging devices. Using these devices together with small samples of tears, intraocular fluid, and tissue, the lab carries out clinical research to diagnose and evaluate eye diseases and systemic diseases.
*Illustrative imageDiagnosing eye diseases with imaging devices
In keratoconus, anterior segment imaging devices make early detection easier, and clarification of risk factors is expected. In Harada disease, disease activity is evaluated from the anterior chamber flare value measured with a flare meter and from choroidal thickness.
*Illustrative imageAnalysis of small samples such as intraocular fluid
The lab diagnoses infections, tumors, and inflammatory diseases from small samples of tears, intraocular fluid, and tissue. It tests for DNA of human herpesviruses and protozoa all at once using multiplex PCR, and analyzes cells in intraocular fluid by methods such as flow cytometry.
MembersFaculty
- Professor, Endowed ChairTakatoshi Maeno
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Optical coherence tomography conducted using the Ultreon 1.0 Software” Cath Lab / CC BY-SA 4.0 (cropped)
- Diagnosing eye diseases with imaging devices: “Computerised Corneal Topography” en:User:Jason7825 / Public domain (cropped)
- Analysis of small samples such as intraocular fluid: “Flow Cytometer (NIH BioArt 160)” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
- Related lab (Drug Discovery Neuroscience Lab): “Drug discovery cycle 2” Boghog / CC BY-SA 4.0 (cropped)
- Related lab (Clinical Gene Therapy Lab): “AAV Gene Therapy” George Church / CC BY-SA 3.0 (cropped)
- Related lab (Disease Data Science Lab): “Cdnaarray” Mangapoco / CC BY 2.5 (cropped)
- Related lab (Visual Function Reconstruction Lab): “EpiretinalMembrane OCT” Jmarchn / CC BY-SA 3.0 (cropped)
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