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864 labs · 42 student voices
Shozo Furumoto, Professor
0 student voices
The Molecular Kinetics Analysis Lab, as the Nuclear Pharmacy Division of the Center for Advanced Quantum Beam Science, studies the use in the life sciences of radionuclides produced by a cyclotron. The lab aims to use PET imaging, which employs short-lived positron-emitting nuclides, in medical diagnosis and drug discovery research. Based on basic research on the design and synthesis of labeled compounds, the lab works on developing new diagnostic probes for PET and evaluating them with small-animal PET. As a cooperating division of the Department of Pharmaceutical Life Sciences in the Graduate School of Pharmaceutical Sciences, the lab accepts undergraduate and graduate students in pharmacy.
Ming-Rong Zhang, Visiting Professor
0 student voices
The Molecular Imaging Pharmaceutical Sciences Lab is part of the Collaborative Department of Molecular Imaging Pharmaceutical Sciences in the Graduate School of Pharmaceutical Sciences, and works in partnership with the National Institute of Radiological Sciences at the National Institutes for Quantum Science and Technology (QST). The research topics listed for the lab include the drug-discovery-oriented development of radiopharmaceuticals and exploratory research. The targets are agents aimed at detecting the function of the brain defense system, agents that capture intracellular signal transduction, and agents used to evaluate tumor malignancy and drug sensitivity. The department's page lists Visiting Professor Ming-Rong Zhang as a faculty and staff member.
Takuya Sasaki, Professor
0 student voices
The Pharmacology Lab studies the neural circuits that underlie brain functions such as memory and emotion, using a wide range of techniques from the molecular level to behavior. When neural circuits stop working normally, they can lead to diseases such as depression, but the exact targets of many therapeutic drugs are still unclear. The lab therefore aims to find the root causes of diseases and targets for drug discovery, based on an understanding of neural circuits. Through brain research, the lab also aims to train talent who can be active in a variety of settings.
Tomoyuki Oe, Professor
0 student voices
The Clinical Analytical Chemistry Lab studies how to build analytical systems for examining minute changes in proteins and peptides involved in disease. The lab also works on how minute changes in proteins and peptides affect disease states, and on the analysis of chemically modified proteins. It also lists as a research goal the development of practical new analytical methods, using needs as the starting point (seeds) for research. In addition, the lab takes up basic research in clinical analytical chemistry as a research topic.
Asuka Inoue, Professor
0 student voices
The lab studies G protein-coupled receptors (GPCRs), which are major drug targets, and the molecules that function downstream of them. By clarifying the diverse roles GPCRs play at the structural, cellular, and organismal levels, the lab aims to identify new drug targets and create better therapeutics. The lab specializes in methods that detect the activation of GPCRs and their downstream signaling in cultured cells, and combines them with genetics such as genome editing, as well as biochemistry, pharmacology, structural biology, and cell biology. Professor Inoue also serves as a Professor at the Graduate School of Pharmaceutical Sciences, Kyoto University.
Hidetaka Akita, Professor
0 student voices
The lab analyzes how drugs move and are eliminated in the body and within cells, and studies technologies to control that movement. The aim is for all kinds of drugs, from small molecules to various macromolecules, to work as effectively as possible with fewer side effects. The goal is to develop drug delivery systems (DDS) that control the movement of molecules in the body and in cells, and thereby contribute to next-generation gene and RNA drug discovery. The lab wants to advance collaborative research with researchers outside pharmaceutical sciences, and also welcomes people who graduated from other faculties to join.
Atsushi Matsuzawa, Professor
0 student voices
The lab studies how cells respond to stresses such as reactive oxygen species and ultraviolet light. Depending on the type and degree of stress, cells choose among responses such as surviving, causing inflammation, and dying. When this mechanism breaks down, it can cause serious diseases such as cancer, autoimmune diseases, and neurodegenerative diseases. By clarifying the mechanism, the lab aims to propose new treatments for these diseases.
Yoshiro Saito, Professor
0 student voices
The lab focuses on the roles of trace elements in the body and studies at the molecular level how they protect against reactive oxygen species, which are highly reactive, and toxic substances. Previous research has shown that abnormal metabolism of trace elements is linked to diabetes, cancer, and neurodegenerative diseases. Based on methods from biochemistry and molecular biology, the lab uses genetically modified animals and model cells to conduct research that leads from the identification of disease biomarkers to the development of therapies. The lab is recruiting undergraduate, master's, and doctoral students who aspire to become researchers.
Shoichiro Kurata, Professor
0 student voices
The Biological Function Analysis Lab (Kurata Lab) studies innate immunity, immune memory, intestinal homeostasis, development, and regeneration. Using methods from molecular genetics, biochemistry, and cell biology, the lab investigates at three levels: the whole-organism level using Drosophila, the cellular level using human and other cells, and the level of the molecules at work in them. By clarifying at the molecular level the mechanisms universally shared by living organisms, the lab approaches the "functions of life." By "conducting first-class research while enjoying it," the lab aims to create knowledge that leads the world and to train people who can truly excel.
Nobuyuki Takahashi, Professor
0 student voices
The Clinical Pharmacy Lab investigates the effects and side effects of drug therapy through clinical research and experiments. Holding that studying pharmacy requires a broad understanding of clinical medicine, the lab asks how drugs are positioned in clinical practice and what kinds of development are needed. The goal is to acquire the ability and expertise to communicate with clinical care teams. The lab considers medicines from the patient's perspective, such as recognizing drug side effects and poisoning from a patient's symptoms and even considering drug-drug interactions.
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