LAB LOGA page on LabLog, a review site (not the lab's official page)
Health Chemistry Lab
Machine-translated · View original
The lab explores disease treatments based on the mechanisms of cellular stress responses and cell death.
AboutAbout the lab
Elucidating cellular stress responses to develop therapeutic strategies for disease
The lab studies how cells respond to stresses such as reactive oxygen species and ultraviolet light.
Depending on the type and degree of stress, cells choose among responses such as surviving, causing inflammation, and dying.
When this mechanism breaks down, it can cause serious diseases such as cancer, autoimmune diseases, and neurodegenerative diseases.
By clarifying the mechanism, the lab aims to propose new treatments for these diseases.
Key terms
- Stress-responsive kinase
- A signaling molecule that senses diverse stresses, relays that information inside the cell, and converts it into various responses.
- Trans fatty acids
- A type of fatty acid. There are artificial forms produced during industrial food manufacturing and natural forms produced in ruminant animals.
- Regulated cell death
- Cell death that stressed cells trigger themselves. There are several types, including apoptosis. It is abbreviated as RCD.
- Ferroptosis
- Cell death caused by lipid peroxidation through iron-dependent reactions. It is known to be associated with neurodegenerative diseases, liver diseases, and others.
ResearchResearch themes
The lab investigates the mechanisms of stress response systems, focusing on signaling molecules that sense stress, relay it inside cells, and convert it into various responses. Based on this, the lab aims to understand disease pathology and develop therapeutic strategies.
*Illustrative imageStress Response Systems and Disease Treatment
The lab has found that ASK1, a stress-responsive kinase, promotes inflammation and immune responses via reactive oxygen species. The lab is investigating how immune signaling is regulated according to the intensity of infection-related stress.
*Illustrative imageMechanisms of Trans Fatty Acid Toxicity
The lab is investigating at the molecular level how industrially produced artificial trans fatty acids contribute to the development of disease. The lab has found that they may promote cell death and cause disease, and that natural trans fatty acids are not toxic.
*Illustrative imageMechanisms of Regulated Cell Death and Treatment
The lab is investigating the detailed mechanisms of regulated cell death, including apoptosis, pyroptosis, parthanatos, and ferroptosis. The lab aims to develop new treatments for neurodegenerative diseases, inflammatory diseases, cancer, and other conditions.
MembersFaculty
The members of the Health Chemistry Lab are faculty, students, administrative assistants, and technical assistants.As of 2025
- ProfessorAtsushi Matsuzawa
- Associate ProfessorYusuke Hirata
- Assistant ProfessorJumpei Omi
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Health Chemistry Lab
Molecular and Cellular Biochemistry LabFaculty of Pharmaceutical Sciences, Department of Pharmaceutical Sciences and Department of Pharmaceutical Drug Discovery SciencesElucidation of G protein-coupled receptor signaling mechanis…
Drug Delivery LabFaculty of Pharmaceutical Sciences, Department of Pharmaceutical Sciences and Department of Pharmaceutical Drug Discovery SciencesDevelopment of delivery technologies for gene and RNA drug d…
Biological Structural Chemistry LabFaculty of Pharmaceutical Sciences, Department of Pharmaceutical Sciences and Department of Pharmaceutical Drug Discovery SciencesDevelopment of novel spectroscopic methods for observing bio…
Metabolic Regulation and Pharmaceutical Sciences LabFaculty of Pharmaceutical Sciences, Department of Pharmaceutical Sciences and Department of Pharmaceutical Drug Discovery SciencesMetabolism of the essential trace element selenium; physiolo…The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Onion cells under the fluorescence microscope 3” Kateryna Kot / CC BY-SA 4.0 (cropped)
- Stress Response Systems and Disease Treatment: “Overview of signalling pathway through IRAK4 and the myddosome complex” EldritchKnot / CC BY-SA 4.0 (cropped)
- Mechanisms of Trans Fatty Acid Toxicity: “Rumelenic acid” Nitraus / CC BY 4.0 (cropped)
- Mechanisms of Regulated Cell Death and Treatment: “Apoptosis DU145 cells mosaic” Egelberg / CC BY-SA 3.0 (cropped)
- Related lab (分子細胞生化学分野): “NEUROTENSIN RECEPTOR 2” rcsb pdb / CC BY 4.0 (cropped)
- Related lab (薬物送達学分野): “Redox-Responsive Drug Delivery” BioRender.com / CC0 (cropped)
- Related lab (生物構造化学分野): “Optical microscope for the study of paint fragments” Froselong / CC BY-SA 4.0 (cropped)
- Related lab (代謝制御薬学分野): “Biochemistry laboratory at the Cawthron Institute, Nelson, around 1949” not stated / Public domain (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.