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777 labs · 31 student voices

Ken Nishimura, Professor
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The Gene Regulation Lab studies gene expression, which lies at the foundation of biological phenomena, using biochemical and molecular biological methods. It investigates transcription factors involved in transcriptional regulation, structural remodeling of chromatin (the site of transcription), and the mechanisms of iPS cell induction. As one of its research topics, the lab also studies how brown adipocytes and beige cells differentiate, aiming to contribute to solving obesity. The lab's website states that it provides careful, individual guidance to each graduate student, regardless of which university or department they come from.

Yuichi Shichino, Professor
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The RNA Biochemistry Lab studies a wide range of phenomena involving RNA. In particular, it focuses on translation, the synthesis of proteins from the information in mRNA, and aims to comprehensively understand when, where, and how it takes place. Making full use of genome-wide analysis with next-generation sequencers, everyone in the lab aims to become a researcher who can do both biochemical and molecular biological experiments and computational analysis. The lab was newly established in September 2025 and began full-scale research activities at the University of Tsukuba in April 2026.

Hiromi Yanagisawa, Professor
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The Yanagisawa Lab studies how cells respond to changes in their surrounding environment (the extracellular environment), focusing on vascular cells and tissue stem cells. Building on knowledge and experimental systems related to the extracellular matrix, the main component of the extracellular environment, the lab aims to clarify the molecular mechanisms of cellular responses to environments that change with aging and disease. To lead to new diagnostic technologies and the discovery of therapeutic targets, the lab also collaborates with researchers in imaging, bioengineering, and glycoengineering. On the lab's website, it is presented under the name "Hiromi Yanagisawa Lab."

Masayuki Masu, Professor
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The Masu Lab, part of the Molecular Neurobiology group, aims to clarify the molecular mechanisms that build neural circuits. Brain function rests on neural circuits formed during the fetal period, but how these circuits form is still not well understood. The lab studies the molecules and genes that control the process from neuronal differentiation through axon guidance and the formation of specific synapses to the acquisition of neural function. Based on molecular biology, the lab uses developmental engineering techniques in mice and zebrafish.

Michael LAZARUS, Professor
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The Lazarus-Oishi Lab studies the mechanisms that regulate sleep, as well as drug discovery, centered on the brain pathways linking sleep, wakefulness, and motivation. Using mice, the lab investigates how the caffeine in coffee and tea promotes wakefulness and how sleep affects immunity. In its research on sleep and motivation, the lab combines techniques for manipulating neural activity with light or drugs with in vivo imaging. The lab is located in the International Institute for Integrative Sleep Medicine (WPI-IIIS) at the University of Tsukuba and is jointly led by Professor Lazarus and Associate Professor Oishi.

Tsuyoshi Saitoh, Associate Professor
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The Medicinal Chemistry Lab (Saitoh Group) conducts research aimed at creating innovative molecules that contribute to biology and medical science, with chemistry as its foundation. Using GPCRs (G protein-coupled receptors), which are common drug targets, as a key theme, the lab carries out drug discovery research and chemical biology research on artificially controlling GPCR function. Based on the principle of "controlling living systems at will with chemistry," the lab values the curiosity behind the thought "I want to make a molecule like this!" On the lab's website, it is presented under the name "Kutsumura-Saitoh Lab."

Shuntaro Izawa, Associate Professor
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The Izawa Lab (neuroendocrinology) studies how the endocrine system, through hormones, controls life activities including sleep. Neurons in the hypothalamus of the brain synthesize peptide hormones such as orexin and melanin-concentrating hormone (MCH), and regulate sleep-wake cycles and energy metabolism. Recently, it has become clear that these neurons are also controlled by blood-borne hormones from peripheral organs, such as insulin and leptin. The lab therefore aims to elucidate these mechanisms in the whole living body, not just in the brain. The research combines modern neuroscience techniques with painstaking observation of animal behavior.

Norihiko Ohbayashi, Associate Professor
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Associate Professor Norihiko Ohbayashi's lab studies membrane traffic, the mechanism that transports materials within cells, focusing on small GTPases (low-molecular-weight G proteins). The lab investigates the functions of small GTPases such as Rab and Arf in pigment cells (melanocytes). The entry in the university's researcher directory was last updated in August 2025. Associate Professor Ohbayashi is listed as a researcher in the graduate school's Degree Programs in Medical Sciences (Life Sciences and Medicine Domain).

Atsushi Kawaguchi, Professor
0 student voices
The Molecular Virology Lab studies how influenza virus and SARS-CoV-2 interact with host cells and lead to disease in organs and severe symptoms. The lab investigates the mechanisms of infection from the molecular level at multiple stages: proteins, cells, and organs and whole organisms. The lab combines observation of cells by light microscopy, handling of highly pathogenic strains in a BSL-3 facility, animal models of infection created with genetic modification technology, and analysis of patient samples in collaboration with the affiliated hospital. Students from a variety of backgrounds, not only medicine, take part in the research.

Kazuya Morikawa, Professor
0 student voices
The Microbiology Lab studies how pathogenic bacteria such as staphylococci adapt to hosts and environments, survive, and exert their pathogenicity. The main subject is Staphylococcus aureus, an opportunistic pathogen that lives as a commensal in the human nasal cavity. From perspectives such as "heterogeneity within cell populations" and "dynamics of the nucleoid and cell membrane," the lab approaches the mechanisms of drug resistance and adaptation. Students can join the lab as graduation research students from the School of Medical Sciences or the School of Biological Sciences (Human Biology course), or as master's or doctoral students.
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