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88 labs · 0 student voices
Other departments in School of Medicine and Health Sciences ›Faculties at University of Tsukuba ›
Yuichi Shichino, Professor
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The RNA Biochemistry Lab studies a wide range of phenomena involving RNA. In particular, it focuses on translation, the synthesis of proteins from the information in mRNA, and aims to comprehensively understand when, where, and how it takes place. Making full use of genome-wide analysis with next-generation sequencers, everyone in the lab aims to become a researcher who can do both biochemical and molecular biological experiments and computational analysis. The lab was newly established in September 2025 and began full-scale research activities at the University of Tsukuba in April 2026.
Hiromi Yanagisawa, Professor
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The Yanagisawa Lab studies how cells respond to changes in their surrounding environment (the extracellular environment), focusing on vascular cells and tissue stem cells. Building on knowledge and experimental systems related to the extracellular matrix, the main component of the extracellular environment, the lab aims to clarify the molecular mechanisms of cellular responses to environments that change with aging and disease. To lead to new diagnostic technologies and the discovery of therapeutic targets, the lab also collaborates with researchers in imaging, bioengineering, and glycoengineering. On the lab's website, it is presented under the name "Hiromi Yanagisawa Lab."
Masayuki Masu, Professor
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The Masu Lab, part of the Molecular Neurobiology group, aims to clarify the molecular mechanisms that build neural circuits. Brain function rests on neural circuits formed during the fetal period, but how these circuits form is still not well understood. The lab studies the molecules and genes that control the process from neuronal differentiation through axon guidance and the formation of specific synapses to the acquisition of neural function. Based on molecular biology, the lab uses developmental engineering techniques in mice and zebrafish.
Shuntaro Izawa, Associate Professor
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The Izawa Lab (neuroendocrinology) studies how the endocrine system, through hormones, controls life activities including sleep. Neurons in the hypothalamus of the brain synthesize peptide hormones such as orexin and melanin-concentrating hormone (MCH), and regulate sleep-wake cycles and energy metabolism. Recently, it has become clear that these neurons are also controlled by blood-borne hormones from peripheral organs, such as insulin and leptin. The lab therefore aims to elucidate these mechanisms in the whole living body, not just in the brain. The research combines modern neuroscience techniques with painstaking observation of animal behavior.
Shinji Fukuda, Visiting Professor
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The Metabologenomics field targets the gut environment, which has attracted attention for its links to a wide range of diseases, and studies technologies that can serve as a foundation for disease prevention and treatment. The lab integrates two kinds of information: metagenomic analysis of the gut microbiota using massively parallel sequencers, and metabolomic analysis of gut metabolites using mass spectrometers. Based on this integrated understanding (metabologenomics), the lab aims to create new medical technologies built on controlling the gut microbiota. On the lab's website, it is introduced as the "Metabologenomics" field of the Division of Metabolic Physiology, Transborder Medical Research Center.
Aya Kawasaki, Assistant Professor
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The Molecular Genetic Epidemiology Lab, under the keywords "human genome diversity and disease," aims to elucidate the etiology of connective tissue diseases, which are systemic autoimmune diseases. Some of the inherited differences in DNA sequence between individuals (variants) are thought to be involved in disease susceptibility. Focusing on ANCA-associated vasculitis, systemic lupus erythematosus, and systemic sclerosis, the lab is searching for causes, molecular targets, and biomarkers. Responses to drugs and the occurrence of side effects differ from patient to patient, and the lab also aims to contribute to precision medicine.
Masafumi Muratani, Professor
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The Genome Biology Lab directly analyzes tissue specimens donated by patients, conducting research aimed at elucidating the mechanisms of human diseases and developing therapeutics. The lab has established techniques that enable genomic analysis even of tissue fragments so small that they can barely be seen under a microscope. It uses mouse models for technology development, and applies the experience gained from analyzing them to interpreting data from clinical specimens. Space life science research with JAXA, which has a base in Tsukuba Science City, is also one of the important research areas the lab works on.
Ryo Fujita, Associate Professor
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The Regenerative Medicine field studies the mechanisms that determine the quantity and quality of skeletal muscle. Skeletal muscle not only moves the body; it is also the body's largest organ for energy metabolism and an endocrine organ that exchanges signals with other tissues through the bloodstream. Through its research, the lab aims to develop ways to prevent and treat sarcopenia, the loss of muscle mass and strength with aging. The field belongs to the Space Medicine Division of the Transborder Medical Research Center at the University of Tsukuba.
Seiya Mizuno, Professor
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The Laboratory Animal Science Lab carries the motto “Embryo Manipulation and Genetic Modification” and studies the production and analysis of genetically modified mice. It also develops software to examine the DNA of mice created by genome editing, and works on developmental research such as meiosis and the formation of the three germ layers in early embryos. The lab website lists its location as the Animal Experiment Building of the Laboratory Animal Resource Center at the University of Tsukuba (the website's information dates from around 2016).
Takatsugu Hirokawa, Professor
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The Chemical Biology and IT Drug Discovery Lab studies in silico drug discovery, which advances drug discovery through computer-based calculation. The lab uses both ligand-based methods, which rely on information about compounds, and structure-based methods, which rely on the 3D structure of the target protein. Using docking simulation, molecular dynamics (MD) simulation, and AI and machine learning, the lab works on supporting in silico drug discovery research and on developing a Hit to Lead system. The lab's website introduces it under the name "Hirokawa Lab."
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