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88 labs · 0 student voices
Other departments in School of Medicine and Health Sciences ›Faculties at University of Tsukuba ›
Yosuke Takei, Professor
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The Anatomy and Neuroscience Lab studies the mechanisms of psychiatric disorders such as schizophrenia and autism spectrum disorder. The lab investigates everything from the small scale of molecules to the large scale of brain formation, aiming to lead to treatments and preventive measures. It focuses in particular on the intracellular transport system that carries materials inside neurons, and on the relationship between the immune system and the nervous system. On the lab's website, the lab is introduced under the name "Takei Lab."
Daisuke Matsubara, Professor
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The Diagnostic Pathology Lab conducts research directly linked to clinical practice and studies molecules involved in the development and progression of cancer. With a pathologist's eye, the lab carefully observes cancer heterogeneity, background lesions, minute lesions, early lesions, and the process of progression. The lab proceeds with its analyses by comparing them against the genetic data of its many cancer cell lines, the tissue morphology of xenograft tumors, and drug sensitivity. In addition to research and clinical practice, the diagnostic pathology group engages in various activities, including the Tsukuba Human Tissue Diagnosis Center, which supports pathological diagnosis in the region.
Hiroshi Yamada, Associate Professor
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The Cognitive and Behavioral Neuroscience Lab conducts neuroscience research using monkeys, aiming to understand how human values arise from the brain. In neuroeconomics, a field that combines neuroscience and microeconomics, the lab studies how the brain works when judging whether things are good or bad. Humans and macaque monkeys, a model animal, perform cognitive behavioral tasks, and the lab examines how the brain makes value judgments depending on the degree of thirst or hunger. By manipulating brain activity and examining its effect on judgment, the lab aims to advance the understanding of depression.
Takeshi Sakurai, Professor
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The Molecular Behavioral Physiology Lab studies sleep and wakefulness, feeding behavior, the circadian clock, and emotion and affect through the actions of neuropeptides in the brain. Using genetically modified mice, the lab investigates from the molecular and cellular levels while aiming to understand functions at the level of the whole organism. It also works to clarify the functions of neuropeptides such as orexin, and studies neurons that put mice into a hibernation-like state. On the lab's website, it is introduced as the "Sakurai/Hirano Lab," a lab of the International Institute for Integrative Sleep Medicine (WPI-IIIS).
Katsuyasu Sakurai, Associate Professor
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The Adaptive Physiology Lab studies how information about internal mental and physical states, and about external circumstances and stimuli, is processed in the brain. Living organisms adapt, both consciously and unconsciously, to their internal states and to external circumstances and stimuli. For example, food that goes unnoticed when one is full draws more attention and desire when one is hungry. On the lab's website, the lab is introduced under the name "Liu/Sakurai Lab."
Mitsuaki Kashiwagi, Assistant Professor
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The lab of Assistant Professor Mitsuaki Kashiwagi uses mice to study the neural circuits in the brain that generate REM sleep and the mechanisms that regulate them. Mammalian sleep consists of REM sleep and non-REM sleep, and the mechanisms and functions of REM sleep are considered to be less well understood than those of non-REM sleep. Assistant Professor Kashiwagi and colleagues have identified a brainstem neural circuit that plays an extremely important role in inducing REM sleep, and they are advancing their research starting from this circuit. The lab is also trying to clarify how the cerebral cortex becomes active during REM sleep, using manipulation of neural circuits and imaging.
Shun Nakajima, Project Associate Professor
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The Digital Behavioral Science Lab combines cognitive behavioral therapy with generative AI and the latest technologies, aiming to make mental health support easy for everyone to use and to spread it throughout society. The lab conducts research that integrates clinical psychology, medicine, and information science, and its researchers include people qualified as clinical psychologists, physicians, and nurses. The lab also uses sensing devices that measure gaze, skin potential, and other signals to capture, from multiple angles (multimodally), the mental and physical changes that occur during cognitive behavioral therapy. Graduate students are accepted through the Basic Psychological Science subprogram of the Degree Program in Psychology. The lab does not provide guidance for clinical psychologist training courses.
Shoi Shi, Associate Professor
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The Shi-Iino Lab uses mice and ants to study biological phenomena including the sleep-wake cycle, learning and decision-making, and phenotypic diversification. In mice, the lab investigates the minimal molecular and neural units responsible for sleep and wakefulness, and seeks to determine how well conserved they are by comparing them with other species. In ants, which are social insects, the lab examines the process by which genetically uniform individuals diversify their phenotypes through acquired changes. The lab also uses data science and mathematical models to search for the principles underlying complex biological phenomena.
Sakiko Honjoh, Assistant Professor
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The Honjoh Lab uses mice to study the mechanisms and functions of sleep. Its goal is to answer the fundamental question of why sleep is necessary, even though a sleeping animal cannot protect itself from external enemies and cannot study. The lab focuses in particular on non-REM sleep, the deep sleep that accounts for 80% of sleep. To join as a student, one must enroll in a graduate school at the University of Tsukuba; undergraduate students can take part as part-time research assistants.
Makoto Kobayashi, Professor
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The Molecular Developmental Biology Lab seeks to understand biological phenomena such as development, cell differentiation, disease, and aging through how genes function (gene expression). Its central focus is the mechanisms that determine cell fate and the mechanisms that respond to stress. For its research, the lab uses zebrafish, a fish that is amenable to genetic approaches and from which large numbers of individuals can be readily obtained. The lab's website also introduces it under the name "Kobayashi Lab."
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