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Faculties at Tohoku University ›
Takaaki Abe, Professor
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Professor Takaaki Abe of the lab serves as the project leader of the "Preemptive Medicine for Mitochondria" project under the Moonshot Research and Development Program (Goal 7). The project aims to elucidate the regulatory mechanisms of the "mitochondria–gut bacteria axis," in which mitochondria and gut bacteria work together to regulate human health. It will also develop a noninvasive diagnostic method to examine mitochondrial function, as well as new therapeutic drugs. The project aims for a society where declining mitochondrial function is detected early and addressed through early intervention and treatment with diet, exercise, and drugs.
Atsushi Masamune, Professor
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The Gastroenterology Lab is a division of the Tohoku University Graduate School of Medicine and carries out research on gastrointestinal diseases broadly, from basic research to clinical research. The lab is divided into groups that each handle diseases of one organ: the upper gastrointestinal tract, the lower gastrointestinal tract, the pancreas, and the liver. In the professor's greeting, clinical care, research, and education are described as an indispensable trinity, and the lab aims to bring research results back into patient care. Many residents in specialty training and graduate students are active on the front lines of research and clinical care.
Yoichiro Yamamoto, Professor
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The Artificial Intelligence in Medical Science Lab analyzes medical data of differing nature, such as genomes, medical images, and clinical records, across AI, mathematics, and medical science. The lab aims to elucidate disease mechanisms, discover new treatments, and build systems for choosing the treatment best suited to each individual patient. Research is carried out at two sites: the Seiryo Campus in Sendai and RIKEN in Tokyo. Another goal of the lab is to reconnect the different expertise of medicine, information science, and mathematical science, and to create a place where people can discuss across disciplinary boundaries.
Ritsuko Shimizu, Professor
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The Molecular Hematology Lab studies GATA1, which acts in the differentiation of erythrocytes and megakaryocytes, and GATA2, which acts in the differentiation of hematopoietic stem and progenitor cells and immune cells. In recent years, mutations in the GATA1 and GATA2 genes have been found in hematopoietic disorders such as leukemia, but the relationship between these mutations and disease onset has not been sufficiently verified. The lab therefore analyzes, at the molecular level, how qualitative and quantitative abnormalities of GATA factors cause disease. Research centers on analysis in whole animals using genetically modified animals, with the aim of clarifying the molecular basis of anemia, immunodeficiency disorders, and leukemia.
Mika Sakurai, Professor
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The lab conducts research that helps build the infrastructure needed to advance genomic medicine. It works on human resource development through its own educational programs, aimed at the many types of professionals involved in the genome cohort studies run by the Tohoku Medical Megabank Organization. It is also developing SNP arrays tailored to genome analysis of the Japanese population and collecting large-scale data. The lab also studies the mechanisms of inflammatory diseases, focusing on matrix metalloproteinases (MMPs) and biotin.
Yukinari Kato, Professor
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The lab is a joint research course with Ono Pharmaceutical, and is introduced on the website of the Division of Antibody Drug Discovery in the Graduate School of Medicine. The website describes research on antibody therapy for breast cancer, lung cancer, brain tumors, and other cancers using CasMab, an antibody technology specific to cancer. Among its research results, the website also lists the development of antibodies against receptors such as CCR7, in addition to HER2 and podoplanin. The website also covers CAR-T therapy using antibodies and antibody development by the CBIS method.
Satoru Ebihara, Professor
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The lab studies various areas of rehabilitation medicine from both clinical and basic perspectives. It was formed in 2024 by merging the Division of Physical Disabilities and the Division of Internal Disorders. Graduate students are diverse: in addition to physicians, they include nurses, physical therapists, occupational therapists, speech-language-hearing therapists, registered dietitians, and health and fitness instructors, and there are many international students. Rehabilitation medicine is described as medicine that stays close to patients, continuing to search for ways to bring even some improvement to diseases and disabilities that cannot be cured.
Toshio Miyata, Professor
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The Molecular Medicine and Therapeutics lab works on the development of pharmaceuticals and software as a medical device (SaMD) that uses artificial intelligence (AI). The lab carries out its research and development using the Medicinal Hub, Tohoku University's open innovation hub. As treatment approaches become more diverse, combining engineering and information technologies with chemistry and biology is considered important. The lab's website also introduces it under the names "Miyata Lab" and "Medicinal Hub."
Yoshinori Okada, Professor
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The Medical Engineering and Cardiology lab studies biomedical engineering that supports bodily functions with artificial organs, such as artificial hearts and mechanical circulatory support. The lab is located in the Center for Promotion of Nonclinical Studies at Tohoku University's Institute of Development, Aging and Cancer, and is involved with both the Graduate School of Biomedical Engineering and the Graduate School of Medicine. The lab's website states that the world's first ultrasound cardiac tomography (echocardiography) was invented in this lab. The website also says that the lab is recruiting doctoral and master's students.
Atsushi Shimizu, Professor
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The Integrative Genomic Predictive Medicine lab studies the prediction and prevention of disease based on genome and epigenome information from the Tohoku Medical Megabank Project. The lab considers the genome, which cannot be changed, together with the epigenome and lifestyle habits, which can, and aims to link them to early intervention. The lab works on research that assesses biological age with epigenetic clocks, and research that examines the relationship between polygenic scores and lifestyle habits. The lab also promotes education and outreach on genome research, statistical genetics, and aging research.
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