LAB LOGA page on LabLog, a review site (not the lab's official page)
Integrative Genomic Predictive Medicine Lab (Tohoku Medical Megabank Organization)
Machine-translated · View original
A lab aiming to predict and prevent disease based on the genome and epigenome.
AboutAbout the lab
Connecting the genome that cannot be changed with the lifestyle that can.
The Integrative Genomic Predictive Medicine lab studies the prediction and prevention of disease based on genome and epigenome information from the Tohoku Medical Megabank Project.
The lab considers the genome, which cannot be changed, together with the epigenome and lifestyle habits, which can, and aims to link them to early intervention.
The lab works on research that assesses biological age with epigenetic clocks, and research that examines the relationship between polygenic scores and lifestyle habits.
The lab also promotes education and outreach on genome research, statistical genetics, and aging research.
Key terms
- Epigenetic clock
- A measure that estimates biological age from DNA methylation status
- Polygenic score
- A measure that combines the effects of many genetic variants into a single value representing susceptibility to a disease
- Multi-omics
- An approach that combines data on multiple types of molecules, such as the genome, proteins, and metabolites
ResearchResearch themes
The genome cannot be changed, but the epigenome and lifestyle habits can. By considering both together, this lab aims to realize medicine that leads to disease prediction, prevention, and early intervention.
*Illustrative imageGenetic risk and lifestyle
Based on the large-scale genome data of the Tohoku Medical Megabank Project, the lab analyzes interactions between polygenic scores and the environment and lifestyle habits. This leads to assessing genetic risk tailored to each individual.
*Illustrative imageThe epigenome and biological age
In the Epigenome Data Office, the lab carries out whole-genome DNA methylation analysis. It organizes epigenome data and promotes its use in Japan and abroad, and works on assessing biological age with epigenetic clocks and on intervention studies.
*Illustrative imageDisease prediction with multi-omics and AI
The lab layers image, video, and lifestyle data onto the genome, transcriptome, proteome, metabolome, and metagenome, and develops AI models that predict disease.
*Illustrative imageResearch on aging and biological age
Centered on epigenetic clocks, the lab quantitatively evaluates how lifestyle habits and physical activity affect biological age. It explores how far aging can be controlled.
MembersFaculty
- ProfessorAtsushi Shimizu
- LecturerShiori Minabe
VoicesStudent voices
Ratings and reviews reflect the experiences of individual current or former students, not the lab's official views. Whether a lab has reviews, or how many, says nothing about the lab itself.
Students who take part in an interview may receive a thank-you gift worth ¥1,000, regardless of what they say.
Student ratings (0 students)
--
--
--
--
--
--
Student voices answer questions like these
- What's great about this lab?
- What did you learn after joining?
- What's the vibe, and what is the professor like?
- Who is this lab for?
- Where do graduates go?
Your experience can help younger students choose their lab. Your name won't be shown.
Write a lab reviewAnonymous · Your draft is saved if you stopRelatedLabs similar to Integrative Genomic Predictive Medicine Lab (Tohoku Medical Megabank Organization)
Clinical Epidemiology Lab (Tohoku Medical Megabank Organization)Faculty of Medicine, School of MedicineClinical epidemiology: evidence generation and social implem…
Genome Preventive Medicine Lab (Tohoku Medical Megabank Organization)Faculty of Medicine, School of MedicineGene regulatory mechanisms and regulatory genomics: cell-spe…
Personalized Prevention and Epidemiology Lab (Tohoku Medical Megabank Organization)Faculty of Medicine, School of MedicinePersonalized preventive medicine and epidemiology; community…
Developmental Neuroscience Lab (Center for Creative and Applied Medicine)Faculty of Medicine, School of MedicineMolecular mechanisms of brain development and evolution; gen…The information on this page is compiled by the LabLog team from the lab's public information and interviews. For corrections or removal requests, please contact LabLog, not the lab.
Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Illumina NextSeq 500” Konrad Förstner / CC BY 2.0 (cropped)
- Genetic risk and lifestyle: “DNA Helix CPK” Ude / Public domain (cropped)
- The epigenome and biological age: “Epigenetic mechanisms” National Institutes of Health / Public domain (cropped)
- Disease prediction with multi-omics and AI: “Typical-workflow” Volkdentoklin / CC BY-SA 4.0 (cropped)
- Research on aging and biological age: “Elderly woman walking towards the camera on a snowy walkway, Promenadeplatz, Munich, Germany julesvernex2” Jules Verne Times Two / CC BY-SA 4.0 (cropped)
- Related lab (Clinical Epidemiology Lab (Tohoku Medical Megabank Organization)): “Mother and newborn baby, Moscow, Russia” Vyacheslav Argenberg / CC BY 4.0 (cropped)
- Related lab (Genome Preventive Medicine Lab (Tohoku Medical Megabank Organization)): “Laboratory microcentrifuge tubes and pipette tips 02” Gannu03 / CC BY-SA 4.0 (cropped)
- Related lab (Personalized Prevention and Epidemiology Lab (Tohoku Medical Megabank Organization)): “Pacific Partnership 2024-1- Community Health Engagement in Fefan (8196722)” U.S. Navy photo by Petty Officer 2nd Class Jacob Woitzel / Public domain (cropped)
- Related lab (Developmental Neuroscience Lab (Center for Creative and Applied Medicine)): “SUM 110913 Cort Neurons 2.5d in vitro 488 Phalloidin no perm 4 cmle-2” Howard Vindin / CC BY-SA 4.0 (cropped)
About LabLog
LabLog is a lab review app for students only. Student members at each university interview students in labs and publish what they say. Student voices can only be read by students who sign up with a university email address. Operated by bestiee Inc.
Learn more about LabLog ↗Search engines and AI may reference the basic lab info and rating summaries on this page and the description of LabLog. Student voices are for student members only. Automated collection by programs (scraping, or input to or training of AI) is prohibited under Article 8 of the Terms of Service. If you need data for research or analysis, please contact us.