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Antibody Drug Discovery Joint Research Lab
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A lab that studies the development of cancer-targeting antibodies and antibody therapy.
AboutAbout the lab
Creating cancer-specific antibodies and exploring treatments.
The lab is a joint research course with Ono Pharmaceutical, and is introduced on the website of the Division of Antibody Drug Discovery in the Graduate School of Medicine.
The website describes research on antibody therapy for breast cancer, lung cancer, brain tumors, and other cancers using CasMab, an antibody technology specific to cancer.
Among its research results, the website also lists the development of antibodies against receptors such as CCR7, in addition to HER2 and podoplanin.
The website also covers CAR-T therapy using antibodies and antibody development by the CBIS method.
Key terms
- CasMab
- The name of a method for producing cancer-specific antibodies. It appears in the names of antibodies against HER2 and podoplanin
- Podoplanin
- A protein on the cell surface. It is presented as a target for antibody therapy of brain tumors and lung cancer
- CAR-T
- A treatment method in which T cells (immune cells) are genetically modified to give them the ability to recognize cancer
NewsLab news
Multiple papers on new antibodies published as outcomes of Smart Bio
Paper on a new anti-mouse CXCR2 antibody published in a scientific journal
Paper showing that a CD44v6 antibody is effective against colorectal and gastric cancer published in Cells
An assistant professor received the Young Investigator Award at the Japan Society of Cancer Metastasis
Paper on the effects of a humanized anti-podoplanin antibody against lung cancer and brain tumors published
ResearchResearch themes
Aiming for antibody-based cancer treatment, the lab studies the development of antibodies specific to cancer cells and analyzes how they work. Research on CAR-T therapy using the antibodies it has developed is also presented among its research results.
View More ↗MembersFaculty
The members page, shared with the Division of Antibody Drug Discovery, introduces faculty, specially appointed professors, academic researchers, doctoral, master's, and undergraduate students, technical assistants, and administrative assistants.As of 2026
- ProfessorYukinari Kato
- Specially Appointed ProfessorMika Kaneko
- Associate ProfessorHiroyuki Suzuki
- Assistant ProfessorHiroyuki Satofuka
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images.
- Top image: “Protein RAD9A PDB 3A1J” Pleiotrope / Public domain (cropped)
- Related lab (Pediatric Pathophysiology Lab): “Visit of Stella Kyriakides, European Commissioner, to the Bambino Gesù Children's Hospital - 2024” Elisabetta Villa / European Union, 2024 / EC - Audiovisual Service / CC BY 4.0 (cropped)
- Related lab (Emergent Medicine Lab (SiRIUS Institute of Medicine)): “Barbara McClintock ( ) shown in her laboratory in 1947” Smithsonian Institution/Science Service; Restored by Adam Cuerden / Public domain (cropped)
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