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129 labs · 0 student voices
Other departments in Faculty of Medicine ›Faculties at Tohoku University ›
Takahiro Arima, Professor
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The lab of Professor Takahiro Arima in the Division of Informative Genetics studies the development and function of the placenta, which is essential for fetal survival. This lab was the first in the world to succeed in establishing human trophoblast stem (TS) cells. Using these cells, the lab investigates the mechanisms of placental development and differentiation, and how diseases related to placental abnormalities arise. Its research themes also include mammalian evolution, genomic imprinting, and the safety of assisted reproductive technology.
Eikan Mishima, Professor
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The Division of Environmental Medicine is a lab that investigates, from molecules to whole organisms, how the environment affects human health and disease. Its main keywords are ferroptosis, a form of cell death, redox regulation, oxidative stress, and drug discovery applications. Ferroptosis is a cell death that arises from the dual nature of iron, oxygen, and lipids. In cancer, inducing it is expected to serve as a treatment strategy, while in conditions such as organ injury, suppressing it may lead to treatment. This long-established division originated from the Department of Hygiene at Tohoku University, and Professor Eikan Mishima joined it in April 2026.
Masayuki Yamamoto, Professor
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The Molecular Medical Biochemistry Lab, as the Division of Molecular Medical Biochemistry in the Tohoku Medical Megabank Organization, studies how living organisms protect themselves from oxidative stress. On the theme of the molecular basis of regulation of the KEAP1-NRF2-sMAF system, the lab held a symposium at the Annual Meeting of the Japanese Biochemical Society. The lab has also published a paper on an experiment in which Nrf2-knockout mice stayed in space and returned alive, and it works on space medicine research as well.
Atsushi Masamune, Professor
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The lab studies stress-related diseases as a field of behavioral medicine, which investigates the relationship between disease and behavior or psychology. Its distinctive feature is that it investigates stress from the perspective of the psychosomatic correlation, in which the mind and body influence each other. A representative disease of the psychosomatic correlation is irritable bowel syndrome, which is considered one of the diseases in which the interaction between the brain and the gut is disrupted. The lab also works on stress-related psychological trauma, maternal separation, and eating disorders.
Mayu Takahashi, Professor
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The lab studies how the brain selects information that enters the eyes and converts it into the behavior of eye movements. When looking at something, the brain unconsciously switches among multiple types of eye movements, including saccades, fast eye movements that shift gaze to a target all at once. Mainly using monkeys, the lab examines neural circuits with physiological and anatomical methods, aiming to clarify the mechanisms in the brain that convert visual input into eye movement output. Combining behavioral, cognitive, and neurophysiological methods in both humans and animals, the lab addresses how the brain links seeing and acting.
Juro Sakai, Professor
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The Molecular Metabolism and Physiology Division (Sakai Lab) studies how lifestyle-related diseases arise, from the perspective of the epigenome, which regulates gene function. The epigenome refers to genetic information that is maintained by DNA methylation and histone modification, separately from the DNA base sequence. It has been suggested that lifestyle is remembered in the epigenome and is a key factor in the onset of lifestyle-related diseases and glucose and lipid metabolism disorders. Through epigenome analysis, the lab clarifies sleep, energy metabolism, and their regulatory mechanisms, and takes on the challenge of developing treatments for lifestyle-related diseases.
Sohtaro Mimasaka, Professor
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The Forensic Medicine Division studies causes of death, identity, and effects on the body through forensic autopsies, analysis of drugs and poisons, DNA testing, and postmortem imaging. The lab also conducts research on documenting, as evidence, injuries sustained by living people, such as in child abuse cases. Please note that the lab does not accept forensic examination requests from members of the public.
Hisatoshi Sugiura, Professor
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The Respiratory Medicine Lab handles a wide variety of respiratory diseases, including asthma, chronic obstructive pulmonary disease (COPD), lung cancer, diffuse lung disease, and respiratory infections. With rapid population aging, the number of patients with respiratory diseases is expected to increase further. In collaboration with basic science departments and the Tohoku Medical Megabank Organization, the lab is advancing research toward biomarker development and drug discovery for intractable respiratory diseases. Recently, the lab has also been focusing on research into diffuse lung diseases and respiratory infections.
Yoshifumi Saijo, Professor
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The Saijo Lab (medical imaging) studies medical imaging technologies, centered on ultrasound, that examine organs inside the body without damaging it. The lab combines a wide range of engineering methods, from the design of ultrasound transducers to signal and image processing, optical systems, and artificial intelligence. Its goal is to see in greater detail the spatiotemporal variation of flow inside the body, capillary networks only tens of microns in size, structural changes inside living cells, and the three-dimensional structure of blood vessels. Graduate students from the Graduate School of Biomedical Engineering and the Graduate School of Medicine research together in the same lab.
Takaaki Abe, Professor
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Professor Takaaki Abe of the lab serves as the project leader of the "Preemptive Medicine for Mitochondria" project under the Moonshot Research and Development Program (Goal 7). The project aims to elucidate the regulatory mechanisms of the "mitochondria–gut bacteria axis," in which mitochondria and gut bacteria work together to regulate human health. It will also develop a noninvasive diagnostic method to examine mitochondrial function, as well as new therapeutic drugs. The project aims for a society where declining mitochondrial function is detected early and addressed through early intervention and treatment with diet, exercise, and drugs.
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