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Molecular Medical Biochemistry Lab
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A lab that studies, at the molecular level, how the body protects itself from oxidative stress.
AboutAbout the lab
Exploring how the body protects itself from oxidative stress
The Molecular Medical Biochemistry Lab, as the Division of Molecular Medical Biochemistry in the Tohoku Medical Megabank Organization, studies how living organisms protect themselves from oxidative stress.
On the theme of the molecular basis of regulation of the KEAP1-NRF2-sMAF system, the lab held a symposium at the Annual Meeting of the Japanese Biochemical Society.
The lab has also published a paper on an experiment in which Nrf2-knockout mice stayed in space and returned alive, and it works on space medicine research as well.
Key terms
- Oxidative stress
- The burden that arises when oxidation progresses in the body and damages cell components
- Nrf2-knockout mice
- Mice engineered so that they do not have the Nrf2 gene
NewsLab news
Doctoral and master's students won Excellent Presentation Awards at the Retreat Graduate Student Research Presentation Meeting
Associate Professor Takafumi Suzuki won the 24th Sugita Genpaku Award
Doctoral and master's students won Excellent Presentation Awards for Young Researchers at the 98th Annual Meeting of the Japanese Biochemical Society
A doctoral student won the Shin'yu Excellent Student Award for fiscal year 2025
A doctoral student won the Takahashi Memorial Award
ResearchResearch themes
The lab investigates the Keap1-Nrf2 system, which plays an important role in regulating the body's response to oxidative stress, in terms of both its molecular-level regulatory mechanisms and its physiological functions. The approaches include biochemical and molecular biological analysis, whole-animal analysis using mice, and structural biology.
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MembersFaculty
The members of the Molecular Medical Biochemistry Lab consist of faculty, postdoctoral researchers, doctoral, master's, and undergraduate students, collaborating staff, research assistants, and administrative staff.As of 2026
- ProfessorMasayuki Yamamoto
- Associate ProfessorTakafumi Suzuki
- Associate ProfessorKeiko Taguchi
- LecturerAkihito Otsuki
- Assistant ProfessorLiam Baird
- Assistant ProfessorRyo Kurosawa
- Assistant (Joshu)Shika Ikura
- Assistant ProfessorTakanori Hidaka
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Biochemistry laboratory MPI-CBG-panorama” Masur / CC BY-SA 3.0 (cropped)
- How Nrf2 works: “Structural studies of Ets-1 Pax5 complex formation on DNA - Pax5 Ets Binding Site on the mb-1 promoter (DNA) 1K78” Garvie CW, Hagman J, Wolberger C / CC0 (cropped)
- Related lab (Medical Biochemistry Lab): “Pipette de laboratoire sur fond blanc au Bénin 03” Adoscam / CC BY-SA 4.0 (cropped)
- Related lab (Oxygen Medicine Lab (Affiliated Center for Innovative Applied Medicine)): “In the Biochemistry Laboratory” Tristan Ferne from UK / CC BY 2.0 (cropped)
- Related lab (Environmental Medicine Lab): “Disposable Pipette Tips in Laboratory Tip Boxes 02” Gannu03 / CC BY-SA 4.0 (cropped)
- Related lab (Cognitive Physiology Lab (Center for Creative and Applied Medicine)): “Brain Anatomy Model ( )” YVC Biology Department / CC BY 2.0 (cropped)
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