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Psychosomatic Medicine Lab
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A lab that explores how diseases arise from the connections among stress, the brain, and the gut.

AboutAbout the lab
Exploring the relationship between stress and the body from a neuroscience perspective.
The lab studies stress-related diseases as a field of behavioral medicine, which investigates the relationship between disease and behavior or psychology.
Its distinctive feature is that it investigates stress from the perspective of the psychosomatic correlation, in which the mind and body influence each other.
A representative disease of the psychosomatic correlation is irritable bowel syndrome, which is considered one of the diseases in which the interaction between the brain and the gut is disrupted.
The lab also works on stress-related psychological trauma, maternal separation, and eating disorders.
Key terms
- Psychosomatic correlation
- The relationship in which the state of the mind and the state of the body influence each other
- Irritable bowel syndrome
- A disease in which the interaction between the brain and the gut is disrupted. This lab treats it as a representative disease of the psychosomatic correlation model
- Cerebral evoked potentials
- Electrical responses recorded as brain activity when a stimulus is received
ResearchResearch themes
The lab investigates how stress contributes to physical diseases from the perspective of neuroscience. It aims to clarify the mechanisms of stress-induced diseases and to use that understanding to overcome them.
*Illustrative imageStress and Irritable Bowel Syndrome
The targets are diseases affected by stress. In irritable bowel syndrome, a representative disease of the psychosomatic correlation, stimulation of the viscera activates brain regions different from the usual ones, and this is thought to be involved in visceral hypersensitivity.
*Illustrative imageBrain Changes and Overcoming Stress-Related Pathology
The lab has succeeded in capturing the brain changes caused by visceral stimulation with both brain imaging and cerebral evoked potentials. It also works on psychological trauma, maternal separation, alexithymia, inflammation-induced sensitization, and eating disorders, aiming to overcome these conditions by controlling key substances.
MembersFaculty
- ProfessorAtsushi Masamune
- Associate ProfessorMotoyori Kanazawa
- LecturerYasuhiro Sato
- Assistant (Joshu)Shunya Moue
- Assistant (Joshu)Kan Goto
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “FMRI coronal scan of Nathanial Bradford” Nathanial Luceus / CC BY 2.0 (cropped)
- Stress and Irritable Bowel Syndrome: “Human stress” Becky Wetherington BLW Photography on Flickr / CC BY 2.0 (cropped)
- Brain Changes and Overcoming Stress-Related Pathology: “EEG electrode” Gspilich2 / CC BY-SA 3.0 (cropped)
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- Related lab (Medical Biochemistry Lab): “Pipette de laboratoire sur fond blanc au Bénin 03” Adoscam / CC BY-SA 4.0 (cropped)
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