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29 labs · 1 student voices
Other departments in Faculty of Pharmaceutical Sciences ›Faculties at Tokyo University of Science ›
Shuji Shimada, Professor
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The Shimada Lab conducts research aimed at providing clinical practice with information for the proper use of medicines. Using meta-analysis, a statistical method that collects and analyzes data from past clinical studies, the lab evaluates whether drug usage and treatments are truly effective. In the fifth year, students look for research seeds during their training at hospitals and pharmacies. In the sixth year, they build on these seeds to conduct experimental research, such as proposing new hospital-prepared formulations and examining dosing methods.
Satoru Goto, Professor
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The Goto Lab studies how the components of drugs behave in solution from the viewpoint of physical chemistry. The lab explains that when structural formulas are viewed as geometric figures, drug molecules can be seen moving around like gymnasts performing on apparatus. The lab thinks this movement may be linked to biological activity and therapeutic effects, and investigates it using computers, NMR, and X-ray crystallography. The lab is listed among the labs of both the Department of Pharmacy and the Department of Pharmaceutical Life Sciences in the Faculty of Pharmaceutical Sciences.
Akiyoshi Saitoh, Professor
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The Saitoh Lab studies why mental and brain disorders such as depression and anxiety disorders arise, from the standpoint of pharmacology, which examines how drugs affect the functions of the body. Through experiments using animal models of disease and tissue, the lab identifies the neural circuits and biological substances involved. Based on these findings, the lab aims to develop new therapeutic drugs and preventive methods. The lab also conducts joint research with outside research institutions, including the International Institute for Integrative Sleep Medicine at the University of Tsukuba and the National Center of Neurology and Psychiatry.
Kyohei Higashi, Associate Professor
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The Higashi Lab studies the structure and function of glycans attached to the proteins that make up our bodies. About 70% of proteins carry glycans, but their structural diversity makes analysis difficult, and their functions remain largely unclarified. For glycans extracted from biological samples, the lab examines structure and functionality using reliable, highly sensitive analytical methods. The lab also takes on developing new trace analysis methods, aiming to elucidate pathological mechanisms from the changes in glycan structure that accompany disease.
Tatsuya Higashi, Professor
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The Higashi Lab aims to extract information on extremely small amounts of biomolecules from samples that place little burden on subjects, such as saliva, and to apply it to disease diagnosis and treatment. The amounts involved are at the picogram (one trillionth of a gram) level. The lab takes on this challenge based on high-performance liquid chromatography–mass spectrometry. The field of specialization is analytical science, and the research field is clinical analytical science.
Shingo Sakurai, Professor
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The Sakurai Lab works on quality assurance of pharmaceuticals and regenerative medicine products from two sides: research on standards and human resource development. It is a social collaboration chair established at Tokyo University of Science in July 2020, aiming to support stronger collaboration among industry, government, and academia through education and research on the quality and GMP of pharmaceuticals and related products. The lab's mission is to promote regulatory harmonization through research on global standards and guidelines, and to apply the latest knowledge gained to human resource development. On the lab's website, it is introduced under the name “Pharmaceutical Quality and GMP Chair.”
Yohei Kawano, Lecturer
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The Pharmacotherapeutics Lab studies how drugs should be used by examining how people respond when they are given a drug. The lab confirms these responses using pharmacoepidemiology methods and tests the reasons behind them in basic research using cultured cells and laboratory animals. The lab designs studies to answer pharmacists' clinical questions and carries them out jointly with clinical sites. Lecturer Yohei Kawano's research topics include data-driven drug repositioning, which re-evaluates existing drugs to find new indications.
Yoichiro Isohama, Professor
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To establish treatments for intractable respiratory diseases rooted in chronic inflammation, such as bronchial asthma and COPD (chronic obstructive pulmonary disease), the Isohama Lab studies how these disease conditions develop and how drugs act. The lab focuses on searching for new target molecules to normalize airway secretion, and on clarifying the pharmacological characteristics hidden in traditional medicines such as Kampo (traditional Japanese herbal) medicines. Aiming to develop drugs with action profiles different from existing ones, the lab works on creating drugs that regulate the function of aquaporins and drugs that suppress airway mucus secretion.
Noriyasu Hada, Professor
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The Hada Lab studies the components contained in crude drugs and Kampo (traditional Japanese herbal) medicines, as well as the chemical synthesis of glycoconjugates. By examining how components vary within plants and how the components in the crude drugs that make up a Kampo medicine interact with each other, the lab seeks to clarify their usefulness and apply it to human health. The lab chemically synthesizes glycoconjugate glycans found in parasites, using them to clarify how infection occurs, and aims to apply them to vaccines and diagnostic agents. In the researcher information database, the lab is listed under the name "Lab of Crude Drugs and Medicinal Plants."
Takehisa Hanawa, Professor
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The Hanawa Lab studies the development of "patient-friendly formulations" needed in clinical settings. In clinical practice, many "in-hospital preparations" are made, which are formulations that hospitals prepare themselves using ingredients not contained in commercially available drugs. However, it is difficult to develop formulations with supporting evidence within medical institutions. The lab conducts basic research that aims to make high-evidence-level formulations available in a form that medical institutions can prepare themselves, and to move them toward clinical application and commercialization through joint research with medical institutions.
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