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Hada Lab
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A lab that explores naturally derived drugs through the chemistry of medicinal plant and Kampo medicine components and of glycans.
AboutAbout the lab
Focusing on compounds produced by nature.
The Hada Lab studies the components contained in crude drugs and Kampo (traditional Japanese herbal) medicines, as well as the chemical synthesis of glycoconjugates.
By examining how components vary within plants and how the components in the crude drugs that make up a Kampo medicine interact with each other, the lab seeks to clarify their usefulness and apply it to human health.
The lab chemically synthesizes glycoconjugate glycans found in parasites, using them to clarify how infection occurs, and aims to apply them to vaccines and diagnostic agents.
In the researcher information database, the lab is listed under the name "Lab of Crude Drugs and Medicinal Plants."
Key terms
- Crude drugs
- Natural products, such as medicinal plants, that are used as materials for Kampo medicines
- Glycoconjugate glycans
- The sugar portion of molecules in which a glycan, a chain of linked sugars, is bound to a protein or lipid
- Serodiagnosis
- Diagnosis that examines the serum of the blood to determine, for example, whether an infection is present
ResearchResearch themes
The Hada Lab conducts drug discovery research focusing on compounds produced by nature. It works on analyzing the components of plants and Kampo medicines, and on the chemical synthesis of glycans derived from parasites and sponges.
*Illustrative imageSynthesis of parasite glycans and application to serodiagnosis
The lab investigates the antigenicity of glycoconjugate glycans found in Echinococcus species and Schistosoma mansoni. By providing single, homogeneous compounds through chemical synthesis, it aims to clarify how infection occurs and to apply the compounds to vaccines and diagnostic agents.
*Illustrative imageSynthesis of sponge-derived glycolipids
Focusing on the glycans of sponges, the lab synthesizes glycolipids with the goal of finding new biological functions, using anti-inflammatory and antitumor activity as indicators.
*Illustrative imageInvestigating the efficacy of Kampo medicines from their components
The lab investigates which components are responsible for the medicinal effects of Kampo medicines, and whether increases or decreases in efficacy are related to changes in components caused by combinations of crude drugs.
*Illustrative imageAnalyzing variation in the components of medicinal plants
The lab analyzes how the components of medicinal plants (crude drugs) vary depending on the part used and the growth period, which contributes to clarifying the usefulness of drugs produced by nature.
MembersFaculty
- ProfessorNoriyasu Hada
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Maou” Hanabishi / CC BY-SA 3.0 (cropped)
- Synthesis of parasite glycans and application to serodiagnosis: “EB1911 Parasites” Rd. Muir / Public domain (cropped)
- Synthesis of sponge-derived glycolipids: “Green and yellow sea sponges, Antarctica” Steve Rupp, National Science Foundation / Public domain (cropped)
- Investigating the efficacy of Kampo medicines from their components: “Herbal medicine platter” Joegoauk Goa / CC BY-SA 2.0 (cropped)
- Analyzing variation in the components of medicinal plants: “Medicinal herbs garden hospital” User:Mattes / Public domain (cropped)
- Related lab (高橋研究室): “Inside the Medicinal Chemistry Lab ( )” National Center for Advancing Translational Sciences from Bethesda, MD / Public domain (cropped)
- Related lab (櫻井研究室): “Tula Pharmaceutical Factory 04” Пресс-центр Правительства Тульской области. / CC BY 4.0 (cropped)
- Related lab (真野研究室): “Hospital pharmacy, 1970s ( )” University of Liverpool Faculty of Health & Life Sciences from Liverpool, United Kingdom / CC BY-SA 2.0 (cropped)
- Related lab (嶋田研究室): “Paxlovid pills close-up” Intellec7 / CC BY-SA 4.0 (cropped)
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