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12 labs · 0 student voices
Other departments in Faculty of Advanced Engineering ›Faculties at Tokyo University of Science ›
Jiro Toshima, Professor
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The Toshima Lab studies endocytosis and intracellular vesicle transport in the field of cell biology. The lab investigates how endocytosis is controlled by the actin cytoskeleton and how the activity of G protein-coupled receptors is regulated. The lab's website features fluorescence images of endocytosis observed in cancer-like cells. Assistant Professor Hiroki Shimamura has used yeast to analyze the secretory pathway, through which newly synthesized proteins are transported.
Suguru Yoshida, Professor
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The Yoshida Lab conducts broad research in synthetic organic chemistry and chemical biology. With a view to developing methods and molecules that accelerate life science research, the lab takes a unique approach that draws out the properties of diverse elements, aiming to create new technologies. Through "reaction development" based on knowledge of organometallic chemistry and heteroatom chemistry, the lab aims to deepen and advance organic chemistry.
Shinichi Miyagawa, Professor
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The Miyagawa Lab studies sex determination and sex differentiation in animals, as well as the development and differentiation of reproductive organs. These processes are intrinsically programmed into organisms, but they are fine-tuned by various environmental factors and can sometimes change substantially. The lab aims to elucidate these developmental programs while taking into account the influence of the environment. In addition to model organisms such as mice and medaka, the lab also studies wild animals such as fish and reptiles.
Genichiro Arimura, Professor
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The Arimura Lab studies how plants and insects recognize other organisms, combining genetic engineering and ecology. It investigates how the scents (odors) released when pest insects chew on plants mediate communication between plants and insects, and among plants. The lab is working to elucidate these mechanisms and to apply such ecosystem systems to agricultural biotechnology.
Kiminori Shimizu, Professor
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The Shimizu Lab believes that controlling microbial functions benefits human life, and it conducts research using methods from genetics and molecular biology. A wide variety of microorganisms live on Earth, and they are deeply involved in our lives in many ways. The number of unknown microbial species is said to be in the millions, estimated at more than tens of times the number of species humans have identified. By discovering such unknown microorganisms, the lab aims to develop microbial functions from multiple angles.
Eri Segi, Professor
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The Segi Lab aims to elucidate, from the molecular, cellular, and whole-organism perspectives, the processes by which neurological and psychiatric disorders, centered on depression, arise and by which treatment takes effect. In antidepressant treatment models, the lab aims to clarify changes in hippocampal function and their contribution. In stress models, it aims to clarify changes in hippocampal circuits and function and their contribution to behavior. In developmental disorder models, the lab aims to evaluate behavior and elucidate changes in brain function. On the lab's website, it is introduced under the name "Segi Lab (Regulation of Biological Functions)."
Koji Tamura, Professor
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The Tamura Lab studies the mystery of how life began on Earth from the perspective of RNA and the genetic code. The genetic code is the system that converts the base sequence of RNA into the amino acid sequence of proteins, and it is shared by all organisms on Earth today. The lab investigates how this code came into being by studying reactions such as the binding of amino acids to tRNA.
Mitsunori Shiroishi, Professor
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Shiroishi Lab studies the function of proteins such as drug-target receptors and antibodies, revealing it at the molecular and atomic level. The lab gives equal importance to protein engineering, which creates new proteins, and protein science, which seeks to understand how proteins function. Using a variety of methods from molecular biology and biophysics, the lab aims to create useful protein molecules that can contribute to human health. The lab's website also describes it as the "Protein Engineering Lab."
Chiharu Nishiyama, Professor
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Nishiyama Lab studies how gene activity is regulated in cells involved in immunity. Its main subjects are mast cells, which cause allergic reactions, and dendritic cells, which pass information about foreign substances to T cells. The lab also investigates how components derived from fragrances, foods, and gut bacteria affect immune responses.
Tatsuya Nishino, Professor
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Nishino Lab uses structural biology methods to analyze, at the atomic level, how chromosomes, the carriers of genetic information, are accurately passed on to the next generation. Drawing on its knowledge of structural biology, the lab also works on designing proteins with new functions. Examples of its research include structural and functional analysis of the chromosomal passenger complex, which is involved in controlling cell division, and of the kinetochore, the machinery that segregates chromosomes. The lab also lists as research examples structural and functional analysis of the RNA silencing mechanism involved in plant antiviral defense, and the development of novel plastic-degrading enzymes.
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