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Yoshida Lab
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The lab aims to accelerate life science research with new methods in organic synthesis.
AboutAbout the lab
Expanding the possibilities of organic chemistry
The Yoshida Lab conducts broad research in synthetic organic chemistry and chemical biology.
With a view to developing methods and molecules that accelerate life science research, the lab takes a unique approach that draws out the properties of diverse elements, aiming to create new technologies.
Through "reaction development" based on knowledge of organometallic chemistry and heteroatom chemistry, the lab aims to deepen and advance organic chemistry.
Key terms
- Aryne
- A synthetic intermediate in which part of a benzene ring has become a triple bond, showing unusual reactivity
- Click reaction
- A reaction that reliably links molecules together. It is used in methods that build molecules by combining multiple components
ResearchResearch themes
With a view to developing methods and molecules that accelerate life science research, the lab conducts broad research in synthetic organic chemistry and chemical biology. Using a unique approach that draws out the properties of diverse elements, it aims not only to solve individual problems but also to create new technologies that bring innovation to organic chemistry and related fields.
*Illustrative imageReactions via cationic intermediates
As reactions that proceed via cationic intermediates, the lab works on transformations involving C–F bond cleavage and methods for synthesizing sulfur-containing compounds through electrophilic activation.
*Illustrative imageReactions via highly strained intermediates
As reactions that proceed via highly strained intermediates, the lab studies synthetic methods using arynes and transformations via highly strained cyclic alkynes.
*Illustrative imageNew synthetic methods for heteroatom-containing compounds
The lab is developing methods for synthesizing sulfur-containing compounds using transition metal catalysts, as well as new building blocks for the simple synthesis of organophosphorus compounds.
*Illustrative imageControl and application of click chemistry
As approaches to controlling and utilizing click chemistry, the lab studies methods for protecting click-reactive functional groups, multicomponent assembly methods, and new click reactions.
MembersFaculty
The Yoshida Lab consists of faculty members and doctoral, master's, and undergraduate students.As of 2026
- ProfessorSuguru Yoshida
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Conical flask in chemistry lab” Akshaya govindasamy / CC BY-SA 4.0 (cropped)
- Reactions via cationic intermediates: “Fume hood MB” Miha Bukleski / CC BY 4.0 (cropped)
- Reactions via highly strained intermediates: “Benzene-3D-molecular-model-engraved-render-CAS-71-43-2” MolGod Scientific / CC BY-SA 4.0 (cropped)
- New synthetic methods for heteroatom-containing compounds: “Microscopic image of crystals growing from melted sulfur 3” AlexmarPhoto / CC BY 4.0 (cropped)
- Control and application of click chemistry: “Diselenide TLC chromatogram” Daniel Dróżdż / CC BY 4.0 (cropped)
- Related lab (白石研究室): “FAM166C Antibody Staining” The Human Protein Atlas / CC BY-SA 3.0 (cropped)
- Related lab (瀬木研究室): “Hippocampus - DK ATLAS” RAZVAN V. MARINESCU / CC BY 4.0 (cropped)
- Related lab (西山研究室): “Mast Cell (NIH BioArt )” Courtesy of NIAID Ryan Kissinger / Public domain (cropped)
- Related lab (十島研究室): “Cell membrane 18 -- Smart-Servier” Laboratoires Servier / CC BY-SA 3.0 (cropped)
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