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1,294 labs · 618 student voices
Ichinohe Takeshi, Associate Professor
Medicine & Healthcare0 student voices
The Ichinohe Lab studies the immune responses that occur in the body when it is infected with a virus. To help develop more effective vaccines, the lab investigates how the body recognizes viruses. Using an influenza virus infection model, the lab also studies the regulation of mucosal immunity and how the gut microbiota regulates virus-specific immune responses. The lab also works on the mechanisms behind severe COVID-19 and on the development of nasal spray vaccines.
Tokiko Nagamura-Inoue, Associate Professor
Bio & Life Sciences0 student voices
The lab studies the properties of somatic stem cells obtained from the umbilical cord and cord blood, and applies them to immune cell therapy and regenerative medicine. Mesenchymal cells gather at sites of inflammation and damaged tissue, where they suppress inflammation and repair tissue; the lab focuses in particular on those derived from the umbilical cord. In collaboration with the Cord Blood and Umbilical Cord Bank at the Institute of Medical Science Hospital, the lab aims to apply these cells to new treatments. To deliver high-quality cells, the lab also aims to use a cell processing facility to manufacture regenerative medical products and their raw materials.
Atsushi Iwama, Professor
Bio & Life Sciences0 student voices
The lab studies, at the molecular level, how hematopoietic stem cells, which produce blood, replicate themselves (self-renewal). It has become clear that when the mechanisms controlling stem cells break down, many diseases can result, and the lab also works to understand this. In particular, from the perspective of "stem cell aging and disease," the lab investigates how the properties of hematopoietic stem cells change with age and how those changes contribute to the onset of blood cancers. The lab aims to apply its findings to regenerative medicine and cancer treatment.
Hideki Taniguchi, Professor
Medicine & Healthcare0 student voices
The lab uses human iPS cells to create, by artificial means, three-dimensional "organs" composed of many different types of cells. Organ transplantation faces a shortage of donor organs, and the lab aims to develop a new form of transplantation medicine that can replace it. Centered on liver organoids (mini-livers), the lab is also working on preparations for clinical trials, experiments in space, and cancer research.
Waki Toya, Associate Professor
Medicine & Healthcare0 student voices
The Bioethics and Medical Law Lab studies the ethical and social issues that arise in advanced medical science research and clinical practice, as well as the legal issues surrounding research and medical care. Medical law is the field of law concerning medicine and healthcare, and some of its topics overlap with bioethics. The lab's research methods center on literature review, including administrative documents from other countries, legal interpretation, and analysis of court cases. As research ethics specialists at the Institute of Medical Science, the lab also provides research ethics consultation, in which people involved in clinical research bring questions on matters such as ethics review.
Ayana Kon, Associate Professor
Medicine & Healthcare0 student voices
The Hematology and Tumor Biology Lab studies how blood cancers (hematologic malignancies) arise from genetic abnormalities. The lab was launched in May 2024. Using patient samples and mouse models that recapitulate the disease, the lab combines omics and single-cell analyses to examine abnormalities in cancer cells in detail. The lab aims to connect these findings to translational research that benefits clinical practice.
Masahiko Bogaki, Professor
Medicine & Healthcare0 student voices
The lab was established in April 2024 to strengthen the Department of Anesthesiology at the Hospital of the Institute of Medical Science and to improve care for patients in the perioperative period. Anesthesiology deals with the body's responses to the stimulation of surgery and the ways to protect the body from them. Examples include the management of sedation, respiration, circulation, pain, blood coagulation, and metabolism. The lab aims to build the foundation for delivering optimal anesthesia and intensive care when needed, both to patients undergoing general surgery and to patients receiving new treatments at the affiliated hospital.
Hiroaki Ikematsu, Professor
Medicine & Healthcare0 student voices
The Advanced Gastrointestinal Endoscopy Lab conducts cutting-edge research on endoscopy, focusing mainly on gastrointestinal cancer, and develops new endoscopic devices. The lab was established at the Institute of Medical Science in October 2023. Its work spans basic endoscopy research, clinical research, and the development of new devices that can be used in clinical practice. The lab also conducts translational research with a variety of basic science labs within the institute, aiming to create new diagnostic and treatment methods.
Yoshihiro Hirata, Associate Professor
Medicine & Healthcare0 student voices
The Advanced Genome Medicine Lab studies diseases of the digestive organs, including the esophagus, stomach, intestines, liver, bile ducts, and pancreas. Its main targets are inflammatory diseases such as gastritis and colitis, and cancers such as gastric cancer and liver cancer. Focusing on the functions of genes and molecules, the lab clarifies how diseases arise and carries out translational research aimed at new therapies, using mouse models and other approaches. It investigates from many angles, including stem cell differentiation, the proliferation and death of epithelial cells, and interactions with immune cells and pathogens.
(Unregistered) (Unregistered), Professor
Medicine & Healthcare0 student voices
The Advanced Medical Development Promotion Lab supports translational research (TR), which carries the results of basic research generated at universities and elsewhere into clinical application. The lab studies TR from the perspectives of regulatory science, biostatistics, and trial design, and supports development. Its research also covers unprecedented therapeutic seeds, such as gene therapy, oncolytic viruses, cell therapies including regenerative medicine, and new vaccines and immunotherapies. Together with the Translational Research and Clinical Trial Center at the University Hospital, the lab also supports the conduct of clinical trials, including trials for regulatory approval.
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