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Other departments in Faculty of Dentistry ›Faculties at The University of Osaka ›

Shinsuke Ohba, Professor
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The lab aims to understand how bones, cartilage, and teeth are formed and to gain hints for new therapies. It also carries out neurobiological research on taste. The lab combines histology, developmental biology, molecular biology, stem cell biology, mouse genetics, bioinformatics, and other fields without being bound by disciplinary boundaries. In undergraduate education, the lab teaches embryology, general histology, oral histology and embryology, and dental anatomy.

Takahiro Furuta, Professor
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The lab studies the neural mechanisms that support sensation and movement around the mouth and face. The nervous system consists of the peripheral nervous system and the central nervous system (the brain), and it is responsible for perceiving touch and taste and for controlling movement through commands to muscles. The lab investigates the neural mechanisms of "sensory information processing," "motor control," and their integration, focusing mainly on clarifying the structure of neural circuits. It also combines analysis of neural activity with verification of gene expression to approach the research from multiple angles.

Takafumi Kato, Professor
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The Oral Physiology Lab conducts research to clarify the brain and neural mechanisms underlying jaw and oral functions and their disorders. Using both human and animal studies, the lab investigates the physiological mechanisms of functions such as mastication, swallowing, and taste perception, and of disorders such as sleep bruxism and orofacial pain. The lab aims to carry out research that can provide leads for other studies and be returned to clinical dentistry. Research is carried out together with graduate and undergraduate students, and graduate and undergraduate students who want to devote themselves to basic research are welcome to join.

Kenji Hata, Professor
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The Biochemistry Lab centers its research on the development, differentiation, and metabolism of bone, cartilage, and joints. Aiming to build a foundation for developing new treatments for bone and cartilage diseases and for bone metastasis of malignant tumors, the lab studies how bone, cartilage, and joints are regulated at the molecular, cellular, and organismal levels. Using cell biology, molecular biology, genetic engineering, mouse genetics, and morphological analysis, the lab also creates knockout and knock-in mice with genome editing technology and examines their phenotypes. Under the slogan "Nurturing talent that will take flight to the world," the lab is also committed to educating young researchers.

Satoru Toyosawa, Professor
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The Oral and Maxillofacial Pathology Lab works on pathological diagnosis in the oral region and on research to elucidate human diseases. In addition to analyzing pathological tissue, the lab performs molecular pathological analysis using animal models of disease and cells. To raise the level of pathological diagnosis in the oral region and to train specialists, the lab holds joint conferences and training with clinical departments. The lab was formerly called the Department of Oral Pathology.

Shigetada Kawabata, Professor
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The Microbiology Lab studies how bacteria in the mouth, and pathogenic streptococci that enter the body through the mouth, cause disease. Dental caries and periodontal disease, the two major dental diseases, are both bacterial infections, and bacteriological research is regarded as an important issue in dentistry. Going beyond dentistry, the lab analyzes the mechanisms by which disease develops and carries out research that forms the basis for new treatments and preventive methods.

Kazuhiro Takuma, Professor
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The Pharmacology Lab mainly uses animal models of disease for central nervous system disorders to clarify how pathological conditions arise, with the aim of developing better drug therapies. Focusing on the role that environmental factors play in the onset of disease, the lab combines behavioral pharmacology and molecular pharmacology to elucidate the molecular basis of psychiatric and developmental disorders and to develop new therapeutic drugs. The lab is in charge of pharmacology in undergraduate education, and in graduate education it aims to train oral health scientists through pharmacology grounded in neuroscience. The lab's greeting message states the hope to develop, in the near future, into research on "oral brain science" that includes the oral region.

Satoshi Imazato, Professor
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The Dental Biomaterials Lab researches the development of next-generation dental materials and new regenerative and tissue engineering technologies, as well as the application of computer technology to biomechanics. Its research is divided into the development of dental materials, the development of tissue engineering and regenerative medicine technologies, and biomechanics research on dental materials. For many of its research themes, the lab also conducts joint research with various universities and research institutes in Japan and abroad, and with dental material manufacturers.

Masae Kuboniwa, Professor
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The Preventive Dentistry Lab conducts research, education, and clinical practice based on preventive dentistry, the science and technology of preventing oral diseases and maintaining oral function. Its purpose is to contribute to improving people's quality of life (QOL) and extending healthy life expectancy through oral health. In its research, the lab investigates at the molecular level how oral biofilms that cause periodontal disease become more virulent, and how the barrier function of the inner marginal gingival epithelium is regulated. Prevention targets not only disease but also the maintenance of oral functions, such as enjoying meals and conversation.

Mikako Hayashi, Professor
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The Conservative Dentistry Lab aims at dental care that preserves teeth without extracting them, and conducts research toward developing and putting into practical use next-generation dental materials and treatment methods. The core of its research is to scientifically observe the clinical pathology of the various diseases in the field of conservative dentistry and apply this to methods of diagnosis, treatment, and prevention. Research includes building the foundation for caries treatment without drilling, bonding to teeth that have had root canal treatment, periodontal tissue regeneration, and analysis of oral biofilms. The acoustic environment of dental clinics and making the sound of dental drills more pleasant are also among the research themes.
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