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Oral Physiology Lab
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A lab that investigates the functions and disorders of the jaw and mouth from the perspective of the brain and nervous system.
AboutAbout the lab
Unraveling disorders of jaw and oral function through the brain and nerves.
The Oral Physiology Lab conducts research to clarify the brain and neural mechanisms underlying jaw and oral functions and their disorders.
Using both human and animal studies, the lab investigates the physiological mechanisms of functions such as mastication, swallowing, and taste perception, and of disorders such as sleep bruxism and orofacial pain.
The lab aims to carry out research that can provide leads for other studies and be returned to clinical dentistry.
Research is carried out together with graduate and undergraduate students, and graduate and undergraduate students who want to devote themselves to basic research are welcome to join.
Key terms
- Trigeminal system
- The nervous system that governs sensory and motor functions of the jaw and oral system. It is recognized as having specific features that differ from other cranial nerve systems and spinal nerve systems.
- Sleep bruxism
- One of the disorders of jaw and oral function related to sleep. This lab studies its physiological mechanisms.
- Orofacial pain
- Pain that occurs in the mouth and face. It is one of the disorders of jaw and oral function that this lab studies.
ResearchResearch themes
The lab aims to clarify the brain and neural mechanisms underlying jaw and oral functions and their disorders, and to produce results that can provide leads for other research and be returned to clinical dentistry. Research proceeds in two ways: analysis of human functional data and experiments using laboratory animals.
Mechanisms of jaw and oral functions and their disorders
The lab investigates jaw and oral functions such as mastication, swallowing, and taste perception, and disorders such as sleep bruxism, orofacial pain, and obstructive sleep apnea. It studies their physiological mechanisms and the underlying brain and neural mechanisms in both humans and animals.
*Illustrative imageFunction and functional changes of the trigeminal system
The trigeminal system, which governs sensation and movement in the jaw and oral system, is recognized as having specific features that differ from other cranial nerve systems and spinal nerve systems. The lab treats clarifying the postnatal development of its function, recovery from injury, and the mechanisms of functional abnormalities caused by disease as an extremely important theme in clinical dentistry.
*Illustrative imageResearch in both humans and animals
The lab analyzes human functional data to find leads to physiological mechanisms, then clarifies the mechanisms through neurophysiological, behavioral, and immunohistological experiments in laboratory animals. The research connects clinical and basic science.
MembersFaculty
In addition to faculty, the Oral Physiology Lab includes graduate students, young faculty members, and undergraduate students who belong to clinical departments and take part in research.
- ProfessorTakafumi Kato
- Associate ProfessorAyano Katagiri
- Assistant ProfessorHiroto Kuno
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Dental tool work DVIDS264901” Petty Officer 3rd Class Jake Berenguer / Public domain (cropped)
- Function and functional changes of the trigeminal system: “Trigeminal nerve tractography” Yeh, F. C., Panesar, S., Fernandes, D., Meola, A., Yoshino, M., Fernandez-Miranda, J. C., ... & Verstynen, T. (2018). Population-averaged atlas of the macroscale human structural connectome and its network topology. NeuroImage, 178, 57-68. / CC BY-SA 4.0 (cropped)
- Research in both humans and animals: “EMG - SIMI” D. Gordon E. Robertson / CC BY-SA 3.0 (cropped)
- Related lab (顎口腔腫瘍外科学講座): “Circumcision instruments on green cloth in tray - right” Dan Bollinger / CC BY-SA 4.0 (cropped)
- Related lab (生化学講座): “Cartilage from mouse joint” Kevin Mackenzie, University of Aberdeen / CC BY 4.0 (cropped)
- Related lab (予防歯科学講座): “Stock Images Electric Toothbrush” Electric Teeth / CC BY 2.0 (cropped)
- Related lab (顎口腔機能治療学講座): “Team Mildenhall Dental Clinic- Bright smiles lead to mission success (4967541)” U.S. Air Force photo by Airman 1st Class Brandon Esau / Public domain (cropped)
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