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Pharmacology Lab
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A pharmacology lab that uses animal models to investigate the mechanisms of central nervous system diseases.
AboutAbout the lab
Aiming to develop "environmental pharmacology" into "oral brain science."
The Pharmacology Lab mainly uses animal models of disease for central nervous system disorders to clarify how pathological conditions arise, with the aim of developing better drug therapies.
Focusing on the role that environmental factors play in the onset of disease, the lab combines behavioral pharmacology and molecular pharmacology to elucidate the molecular basis of psychiatric and developmental disorders and to develop new therapeutic drugs.
The lab is in charge of pharmacology in undergraduate education, and in graduate education it aims to train oral health scientists through pharmacology grounded in neuroscience.
The lab's greeting message states the hope to develop, in the near future, into research on "oral brain science" that includes the oral region.
Key terms
- Autism spectrum disorder
- A developmental disorder. This lab studies its relationship with environmental factors during pregnancy
- Oxytocin
- A type of hormone. Intranasal administration has been reported to improve the reduced social behavior in ASD model mice
- Sporadic Alzheimer's disease
- A disease that is a leading cause of dementia. Lifestyle-related diseases such as diabetes are considered risk factors
ResearchResearch themes
The Pharmacology Lab mainly targets central nervous system diseases and uses animal models of disease to investigate how pathological conditions arise. Based on the results, it aims to develop better drug therapies and apply them to new pharmacological treatments.
*Illustrative imageMaternal environment and the mechanisms of developmental disorders
The lab focuses on the clinical finding that taking antiepileptic drugs during pregnancy raises the risk of autism spectrum disorder (ASD) in the child. It has found ASD-like abnormal behavior and brain changes in the offspring of pregnant mice given valproic acid, and has reported the possibility of treatment with oxytocin and other agents.
Lifestyle-related diseases and Alzheimer's disease
In sporadic Alzheimer's disease, a leading cause of dementia, lifestyle-related diseases such as diabetes, hypertension, and hyperlipidemia are considered risk factors, but the molecular mechanisms linking the two are still unknown. Using models of lifestyle-related diseases, especially diabetes models, the lab aims to elucidate the molecular mechanisms leading to onset.
MembersFaculty
The Pharmacology Lab's website introduces a professor and an associate professor as staff.As of 2026
- ProfessorKazuhiro Takuma
- Associate ProfessorAtsuko Hayata
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Pipette 0,5 ml nah” Lysippos / CC0 (cropped)
- Maternal environment and the mechanisms of developmental disorders: “Autism Doodle Stimming 2” MissLunaRose12 / CC BY-SA 4.0 (cropped)
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