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42 labs · 3 student voices
Faculties at Tokyo University of Science ›

Hideshi Yokoyama, Professor
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The Yokoyama Lab studies the three-dimensional structures of disease-related proteins and other proteins in order to clarify how they function. The lab also targets proteins that are drug discovery targets, and determines their structures by X-ray crystallography. It also determines the structures of complexes between a protein and a compound (drug) that regulates its function, and aims to design compounds that regulate protein function more efficiently (drug design).

Tomomi Akita, Lecturer
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The Akita Lab studies the construction of DDS that efficiently deliver drugs to the alveoli, with the aim of treating intractable lung diseases. The lab is also developing a Nose-to-Brain system that makes use of neural circuits. Its research field is physical pharmacy, and the listed topics are chronic obstructive pulmonary disease (COPD), inhaled formulations and device design, and central nervous system delivery technology. The lab is introduced as a lab of the Faculty of Pharmaceutical Sciences, Department of Life Sciences and Drug Discovery at the undergraduate level, and the Graduate School of Pharmaceutical Sciences, Department of Pharmaceutical Sciences at the graduate level.
Takuo Ogihara, Professor
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The Ogihara Lab is presented as the lab for "Drug Discovery Resource Development" in the Department of Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences. The lab's faculty member is Professor Takuo Ogihara. Among its recent papers is one that used human cerebrospinal fluid and plasma to examine how easily drugs pass into the brain (blood-brain barrier permeability). Other papers examine the effect of calcium alginate on blood sodium levels and the rise in blood pressure in rats, and P-glycoprotein in lung cancer cell lines.

Shin Aoki, Professor
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The Aoki Lab researches the creation of new drugs and materials based on the chemistry of "supramolecules," in which molecules come together and function as a unit. Taking as its model the phenomenon in nature where molecules assemble spontaneously, the lab aims to open up new organic chemistry and medicinal chemistry from supramolecular chemistry in water. It designs and synthesizes photoreaction-based methods for ultra-early diagnosis and treatment of cancer and infectious diseases, new asymmetric catalysts, and luminescent sensors that use light to signal molecules in the body. Since 2019, the lab has also worked on creating small-molecule drugs against cancer and emerging and re-emerging infectious diseases.

Akiko Nakada, Associate Professor
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The Nakada Lab studies medical ethics, research ethics, and medical education. Its research topics include developing a rehabilitation program for research integrity and verifying its usefulness. The lab also conducts research on the work of pharmacists. The department's lab introduction lists medical ethics, research ethics, and professionalism as fields of study.

Tsugumichi Sato, Professor
0 student voices
The Sato (Tsugumichi) Lab conducts research aimed at evaluating and minimizing the risks of drugs actually used in clinical practice. Choosing the best treatment requires evaluating a drug's benefits (expected effects) and risks (possible side effects). Using drugs more appropriately can reduce risks. The lab conducts research such as pharmacoepidemiology studies that use healthcare big data to examine the safety of drugs after they reach the market.

Akira Sato, Associate Professor
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The Sato (Satoshi) Lab studies the processes that determine whether cells live or die, and the mechanisms of drug resistance in cancer. Founded in April 2018, it is a small lab that takes advantage of its agility in its research. The lab aims to understand how cancer cells die and how they become resistant to anticancer drugs, and to connect this to cancer treatment. It also investigates the modes and mechanisms of retinal cell death, with the goal of protecting retinal cells and controlling cell death.

Yasunari Mano, Professor
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The Mano Lab is a clinical pharmaceutical sciences lab that picks out the various problems faced in clinical practice and aims to elucidate them. Alongside elucidation, it also aims to build new pharmaceutical evidence and feed it back to clinical practice. The lab develops optimal dosing design methods that take into account the pharmacokinetics, efficacy, and side effects of drugs. It also conducts research on the appropriate use of drugs using large-scale healthcare databases (so-called healthcare big data).

Mitsutoshi Tsukimoto, Professor
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The Tsukimoto Lab studies how radiation affects living organisms, from a perspective unique to pharmaceutical sciences. To improve radiation therapy, the lab works to uncover the mechanisms by which cancer cells respond to radiation. The lab also conducts basic research toward developing radioprotectors that protect normal cells from radiation.

Kazumi Yoshizawa, Professor
0 student voices
The Yoshizawa Lab studies palliative care, which eases the suffering of cancer patients, from a pharmaceutical sciences perspective. Palliative care is medical care that listens to the pain and distress cancer patients experience and relieves their symptoms. The lab focuses on the "suffering of mind and body," which is at the core of palliative care. In the researcher database, the lab is listed under the name "Disease Pharmacology Lab."
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