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Aoki Lab
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A lab that creates drugs and catalysts by taking inspiration from how molecules assemble on their own.
AboutAbout the lab
Creating new drugs from the way molecules assemble
The Aoki Lab researches the creation of new drugs and materials based on the chemistry of "supramolecules," in which molecules come together and function as a unit.
Taking as its model the phenomenon in nature where molecules assemble spontaneously, the lab aims to open up new organic chemistry and medicinal chemistry from supramolecular chemistry in water.
It designs and synthesizes photoreaction-based methods for ultra-early diagnosis and treatment of cancer and infectious diseases, new asymmetric catalysts, and luminescent sensors that use light to signal molecules in the body.
Since 2019, the lab has also worked on creating small-molecule drugs against cancer and emerging and re-emerging infectious diseases.
Key terms
- Supramolecule
- A structure in which many molecules come together through weak forces and function as a single unit
- Asymmetric catalyst
- A catalyst that selectively produces only one of two molecules that are mirror images of each other, like a right hand and a left hand
- Luminescent sensor
- A molecule that changes how it glows when it meets a specific molecule or ion, signaling its presence
NewsLab news
A master's student won the Outstanding Student Presentation Award at the 146th Annual Meeting of the Pharmaceutical Society of Japan
A paper was selected as a Featured Article in Chemical and Pharmaceutical Bulletin
An undergraduate student won an Excellent Presentation Award at the 68th Kanto Branch Meeting of the Pharmaceutical Society of Japan
A master's student won the Best Poster Presentation Award at iPoPS2024
ResearchResearch themes
Based on the idea of assembling molecules through intermolecular interactions, the lab develops nanoscale supramolecules and drugs with new structures and functions. It also advances research on tools that use photochemical reactions, and on diagnosis and treatment methods for cancer and infectious diseases.
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MembersFaculty
The members of the Aoki Lab consist of faculty and doctoral, master's, and undergraduate students.As of 2024
- ProfessorShin Aoki
- Contract Special LecturerToshifumi Tojo
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Lab Mol Colloidal quantum dots 01” Lab mol (Ilia Litvinov) / CC BY 4.0 (cropped)
- From molecular assemblies to drugs, catalysts, and diagnostics: “IRMOP-50” JonathanGR29 / CC0 (cropped)
- Related lab (和田・佐藤(一)研究室): “Liberty Blue CEM” Chrumps / CC BY-SA 4.0 (cropped)
- Related lab (内呂研究室): “Inside the Medicinal Chemistry Lab ( )” National Center for Advancing Translational Sciences from Bethesda, MD / Public domain (cropped)
- Related lab (草森研究室): “Line of culture flask ( )” Jean-Etienne Minh-Duy Poirrier from USA / CC BY-SA 2.0 (cropped)
- Related lab (横山研究室): “CSIRO ScienceImage 1304 Protein crystals” division, CSIRO / CC BY 3.0 (cropped)
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