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6 labs · 0 student voices
Faculties at Chiba University ›
Mitsutoshi Yoneyama, Professor
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The Infection Response Project studies the mechanisms of innate immunity against viral and fungal infections. Cells in the body detect pathogens with infection-sensor molecules and quickly mount an immune response. The lab focuses on RLR (RIG-I-like receptor), a viral sensor it identified, and studies how it functions and how its signals are transmitted. The lab aims to obtain findings that could lead to new antiviral therapies in the future.
Shinobu Saijo, Associate Professor
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The Cytokine Project studies the roles cytokines play in the mechanisms by which infectious and inflammatory diseases arise. The body maintains a stable state (homeostasis) through the interaction of many cells and tissues. Many diseases arise not from a single organ but from abnormalities in multiple systems, such as the immune system, so understanding the cytokines that link them is important. The lab's ultimate goal is to find molecules that could become targets for new drugs.
Hiroji Chibana, Associate Professor
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The Candida Phenome Project Lab uses the pathogenic fungus Candida glabrata to study how infection occurs and to search for new drug targets. Candida glabrata is the pathogenic fungus most often found in patients after Candida albicans. Because it has few genes and its genome information is well established, it is the pathogenic fungus whose genes are easiest to study, and the lab uses it as a model organism. The lab has built a library of recombinant strains covering every gene and shares it with researchers in Japan and abroad.
Akira Watanabe, Professor
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The Clinical Infectious Diseases Project Lab deals with fungal diseases, including aspergillosis, through both clinical care and research. It studies them from many angles, including how infection occurs, the development of diagnostic and treatment methods, and epidemiology. The lab researches problems that emerge in clinical practice, with the aim of bringing the results back to the bedside. It also runs a "Mycosis Reference Center," which handles consultations and testing for fungal diseases from medical institutions across Japan.
Naruhiko Ishiwada, Professor
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The Infectious Disease Control Project Lab studies infections caused by Haemophilus influenzae and Streptococcus pneumoniae. It investigates the ability of these bacteria to cause disease (virulence) and continues epidemiological surveys of where and how much infection is occurring. It also conducts clinical research to develop diagnostic and treatment methods for hard-to-treat respiratory infections. The lab also provides clinical care in the University Hospital's departments of pediatrics and infectious diseases and its infection control division, and responds to consultations from inside and outside the university.
Takashi Yaguchi, Associate Professor
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The Bioresource Management Lab studies how to accurately identify molds and yeasts while managing strains of pathogenic fungi. As part of strain management, the lab observes the morphology of pathogenic fungi, performs phylogenetic analysis, and examines differences within the same species. It works on methods to rapidly identify species, both from cultured fungi and from uncultured samples.
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