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Candida Phenome Project Lab
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The lab examines all the genes of the pathogenic fungus Candida to search for new drug targets.
AboutAbout the lab
Finding Candida's weak points across all of its genes.
The Candida Phenome Project Lab uses the pathogenic fungus Candida glabrata to study how infection occurs and to search for new drug targets.
Candida glabrata is the pathogenic fungus most often found in patients after Candida albicans.
Because it has few genes and its genome information is well established, it is the pathogenic fungus whose genes are easiest to study, and the lab uses it as a model organism.
The lab has built a library of recombinant strains covering every gene and shares it with researchers in Japan and abroad.
Key terms
- Pathogenic fungus
- A mold or yeast that causes infections in humans. It tends to be a problem in people with weakened immunity.
- Model organism
- An organism that is easy to work with and is used as a representative for studying mechanisms shared with other organisms.
- Recombinant strain
- A strain of an organism in which genes have been deliberately disrupted or replaced.
NewsLab news
View More ↗ResearchResearch themes
The lab treats Candida glabrata as a model organism for pathogenic fungi and has built a library of recombinant strains covering all of its genes. Using this library, it is working to clarify how infection occurs and to find targets for antifungal drugs that have few side effects and are effective against a wide range of fungi.
*Illustrative imageA recombinant strain library covering all genes
The lab has built a library that systematically collects recombinant strains for every gene of Candida glabrata. The library is used jointly with researchers in Japan and abroad.
*Illustrative imageHow infection occurs and the search for drug targets
Using the recombinant strain library, the lab works to clarify how infection occurs and searches for targets of antifungal drugs that have few side effects and are effective against a wide range of fungi.
MembersFaculty
The members of the Candida Phenome Project Lab are faculty and technical assistants.As of 2026
- Associate ProfessorHiroji Chibana
- Project Assistant ProfessorMichiyo Sato
- Project Assistant ProfessorWei Cao
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Baking yeast cells under 40x microscope objective” ~delta / CC BY-SA 4.0 (cropped)
- A recombinant strain library covering all genes: “Phaffia rhodozyma on PDA plate 01” Awkwafaba / CC BY-SA 4.0 (cropped)
- How infection occurs and the search for drug targets: “Aspergillus terreus Antifungal Susceptibility Testing on Sabouraud Dextrose Agar” Ajay Kumar Chaurasiya / CC0 (cropped)
- Related lab (サイトカインプロジェクト): “Dendritic cell revealed” National Institutes of Health (NIH) / Public domain (cropped)
- Related lab (バイオリソース管理室): “Four 3-day old Aspergillus colonies on a Petri dish” Adrian J. Hunter / CC BY-SA 3.0 (cropped)
- Related lab (感染症制御プロジェクト): “Bacterial growth on blood agar” Ajay Kumar Chaurasiya / CC BY-SA 4.0 (cropped)
- Related lab (感染応答プロジェクト): “Influenza A Virus (H1N1)-1” NIH Image Gallery / Public domain (cropped)
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