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87 labs · 0 student voices
Faculties at Hokkaido University ›
Jun Takeuchi, Professor
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The lab studies, at the molecular level, how cell fate is determined and how it is maintained. It aims to clarify how mechanisms that are finely controlled in normal development break down and lead to disease and cancer. Using methods such as multi-omics analysis, the lab works on congenital heart disease, lymphatic vessel disease, and the mechanisms of cancer progression.
Shigetsugu Hatakeyama, Professor
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The lab studies the mechanisms of protein degradation, centered on ubiquitination, a post-translational modification of proteins. Ubiquitination is involved in many bodily functions, including cancer, immunity, intracellular signal transduction, and neuronal differentiation. The lab conducts basic research to identify the enzymes responsible for ubiquitination and characterize their functions, as well as research that clarifies links to disease in order to lead to prevention and treatment.
Miwako Yamasaki, Professor
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The lab studies synapses, which connect neurons in the brain, from both molecular and morphological perspectives. It investigates how the molecules that function at synapses are expressed, and how synaptic circuits develop and are remodeled. In the Faculty of Medicine, the lab is in charge of courses such as gross anatomy dissection and neuroanatomy.
Fumino Fujiyama, Professor
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Based on the idea that "function is reflected in structure," the lab studies the morphology and function of neural circuits in the brain. Its main focus is the circuits linking the cerebral cortex, basal ganglia, and thalamus, which connect learning and movement and support selecting actions suited to the situation. Combining morphological methods with electrophysiology and optogenetics, the lab aims to draw precise maps of brain circuits.
Yusuke Ohba, Professor
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The Cell Physiology Lab uses fluorescence bioimaging to visualize how signals are transmitted inside cells and how cell membranes and organelles move, studying the mechanisms of life at the cellular level. The lab captures and analyzes information that changes moment by moment inside cells, in real time and in living cells. Almost every year, the lab holds a microscopy workshop called the 'Imaging Bootcamp.'
Masaki Tanaka, Professor
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The Neurophysiology Lab studies the brain mechanisms that underlie everyday, seemingly effortless behavior, based on the activity of nerve cells (neurons). Monkeys, whose brains are close to those of humans, perform various tasks, and the lab examines at the level of neurons the information processed in each part of the brain. The lab investigates the roles of the frontal lobe, cerebellum, and basal ganglia in changing behavior according to the situation, sensing time and rhythm, and short-term memory and its updating.
Takeo Yoshikawa, Professor
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The Neuropharmacology Lab studies the mechanisms of sleep and wakefulness and therapeutic drugs for them, focusing on histamine and neuropeptides that act in the brain. The lab develops drugs that inhibit the enzyme that breaks down histamine, aiming to lead to new treatments for hypersomnia and other conditions. It also studies the role of glycans in bodily functions. In the Faculty of Medicine's School of Medicine, the lab is in charge of the lectures and practical training in pharmacology for third-year students.
Koji Taniguchi, Professor
0 student voices
The Integrative Pathology Lab is a pathology lab that approaches the essence of disease through both research and diagnosis. Its central theme is chronic inflammation, and it studies how inflammation is involved in tissue regeneration, cancer, and aging. In addition to examining tissue under the microscope, the lab uses newer technologies such as spatial transcriptomics, single-cell analysis, and organoid culture.
Shinya Tanaka, Professor
0 student voices
The Tumor Pathology Lab studies the mechanisms of disease, centered on cancer, from both pathological tissue and molecular perspectives. Each member pursues research according to their own interests from among research themes in basic medicine, surgical pathology, and clinical medicine, aiming to contribute to clinical medicine. The lab also takes part in pathological diagnosis at the university hospital. Career consultations and lab visits are accepted by appointment.
Koichi Kobayashi, Professor
0 student voices
The Immunology Lab studies how the body detects pathogens such as bacteria and viruses and defends itself. Immune responses prevent infections, but when excessive they can also cause inflammatory diseases. Using innate immune sensors and the function of MHC genes as clues, the lab works on how Crohn's disease develops, how cancer evades the immune system, and the development of new cancer immunotherapies.
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