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Neurophysiology Lab
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The lab explores the sense of time, memory, and behavioral switching through neuronal activity in the brain.
AboutAbout the lab
Understanding higher brain functions through neuronal activity
The Neurophysiology Lab studies the brain mechanisms that underlie everyday, seemingly effortless behavior, based on the activity of nerve cells (neurons).
Monkeys, whose brains are close to those of humans, perform various tasks, and the lab examines at the level of neurons the information processed in each part of the brain.
The lab investigates the roles of the frontal lobe, cerebellum, and basal ganglia in changing behavior according to the situation, sensing time and rhythm, and short-term memory and its updating.
Key terms
- Neuron
- A nerve cell that makes up the brain and nerves. It generates electrical signals and passes information to other cells
- Basal ganglia
- A cluster of nerve cells deep in the cerebrum, involved in regulating movement, learning, and the selection of actions
- Executive function
- The brain function that holds rules in mind and carries out complex tasks while updating and selecting information
NewsLab news
A student won the Young Investigator Award at the Hokkaido Regional Meeting of the Physiological Society of Japan
Paper on frontal lobe neurons involved in erasing short-term memory published in Communications Biology
ResearchResearch themes
The lab aims to understand the brain mechanisms that support everyday behavior, and the disease states in which such behavior becomes difficult, through neural circuits and neuronal activity. It focuses on information processing in broad networks formed by the frontal lobe together with the cerebellum, basal ganglia, and other regions.
*Illustrative imageHow the Brain Senses Time
There is no dedicated sensory organ for measuring time; the sense of time is created within the brain. The lab examines neural activity in the cerebellum, striatum, thalamus, and frontal lobe of monkeys performing tasks that require time information.
*Illustrative imageSwitching Behavior to Suit the Situation
Using a task in which the direction of eye movement is switched according to a rule, the lab examines neural activity in various parts of the brain. It also studies changes in the connections between the cerebrum and the striatum, and how the cerebellum and frontal lobe are involved in detecting errors.
*Illustrative imageNeural Mechanisms of Working Memory and Attention
Complex tasks such as cooking require executive function: remembering rules while continually updating information. In tasks that require short-term memory and information updating, the lab examines neural activity in the frontal lobe and the effects of drugs.
MembersFaculty
The members of the Neurophysiology Lab consist of faculty, postdoctoral researchers, administrative assistants, technical assistants, and doctoral, master's, and undergraduate students.As of 2026
- ProfessorMasaki Tanaka
- LecturerKenichi Okada
- Assistant ProfessorFuko Kadono
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Cortical neurons” Luisa Demarchi, Ilaria Bertocchi, Alessandra Oberto / CC BY-SA 4.0 (cropped)
- How the Brain Senses Time: “Hourglass with sand” John Morgan / CC BY 2.0 (cropped)
- Switching Behavior to Suit the Situation: “Striatum” Images are generated by Life Science Databases(LSDB). / CC BY-SA 2.1 jp (cropped)
- Neural Mechanisms of Working Memory and Attention: “Frontal lobe - lateral view” Anatomography / CC BY-SA 2.1 jp (cropped)
- Related lab (医化学): “Ubiquitin 1UBQ surface” Thomas Splettstoesser (www.scistyle.com) / CC0 (cropped)
- Related lab (神経生物学): “Hippocampus mossy fiber interneuron” National Institutes of Health (NIH) / Public domain (cropped)
- Related lab (神経薬理学): “Diphenhydramine 3D 2aot” Fvasconcellos (talk · contribs) / Public domain (cropped)
- Related lab (腎泌尿器外科学): “Kidney noblood” Sheldahl / CC BY-SA 4.0 (cropped)
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