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Neurophysiology Lab
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A lab studying how the brain regulates blood circulation and breathing.
AboutAbout the lab
Taking on the challenge of uncovering how the brain maintains homeostasis in the body
The Neurophysiology Lab studies the regulation of blood circulation and respiratory movements in order to clarify how the brain maintains homeostasis in the body.
If the brain's control of blood circulation does not work properly, it can cause serious cardiovascular diseases, so the lab works to clarify how this control actually operates.
Using rodent preparations, mainly with electrophysiological methods, the lab examines in detail the brain centers that regulate circulation and breathing.
The lab is recruiting graduate students to conduct research together, and also accepts undergraduate students for graduation research.
Key terms
- Homeostasis
- The function of keeping the body's internal state within a certain range
- Electrophysiology
- A method that measures the electrical signals produced by neurons and other cells to study how they function
- In situ preparation (arterially perfused preparation)
- A preparation in which fluid is perfused through blood vessels so that part of the body can be kept alive and used for experiments
ResearchResearch themes
The lab studies the regulation of blood circulation and respiratory movements in order to clarify how the brain maintains homeostasis in the body. Using rodent in vivo and in situ preparations (arterially perfused preparations), mainly with electrophysiological methods, it analyzes the circulatory and respiratory centers in detail.
*Illustrative imageBrain regulation of blood circulation
Much about how the brain regulates circulation is still unknown. The lab studies how stress affects circulatory regulation, the chemosensitivity of neurons in circulatory control centers, and the relationship between the breakdown of these mechanisms and cardiovascular disease.
*Illustrative imageBrain regulation of respiratory movements
The lab analyzes the respiratory center in detail. It studies the role of hydrogen sulfide in the brain in generating respiration, the control of the circulatory center by the respiratory center (cardiorespiratory coupling), and the diseases caused by the breakdown of this control.
MembersFaculty
The members of the Neurophysiology Lab consist of faculty, visiting researchers, students, and alumni.As of 2026
- Associate ProfessorTadachika Koganezawa
- Assistant ProfessorMinako Okazaki
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “Tektronix 2467 analog oscilloscope (350 MHz)” Department of Energy. National Nuclear Security Administration. Sandia National Laboratories. 3/1/2000 / Public domain (cropped)
- Brain regulation of blood circulation: “Blood pressure monitoring” rawpixel.com / CC0 (cropped)
- Brain regulation of respiratory movements: “2301 Major Respiratory Organs” OpenStax College / CC BY 3.0 (cropped)
- Related lab (遺伝医学): “DNA sequencing” Linda Bartlett (Photographer) / Public domain (cropped)
- Related lab (再生幹細胞生物学): “Laboratory Incubator; from a medical laboratory in Abuja, Nigeria” Frankincense Diala / CC0 (cropped)
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