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Genetic Medicine Lab
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The lab explores how allergies develop, starting from genes, in the field of genetic medicine.
AboutAbout the lab
Exploring the mechanisms of allergy from genes.
The Genetic Medicine Lab uses genetic research methods to clarify the pathology of allergic diseases and other conditions, and conducts research aimed at personalized medicine.
Using genome-wide methods that comprehensively examine the whole genome, the lab searches for genes involved in the onset of asthma, allergic rhinitis, hay fever, and food allergy.
The lab also independently works on developing treatments using the HLA peptide-binding assay.
On the lab's website, it is introduced under the name "Genetic Medicine, Institute of Medicine, University of Tsukuba."
Key terms
- HLA
- A type of gene involved in immune function. Its relationship to the onset of allergic diseases is being studied
- Peptide-binding assay
- An experiment that examines whether a peptide (a short chain of amino acids) binds to HLA
- Personalized medicine
- Medical care tailored to each patient's constitution and disease characteristics
ResearchResearch themes
The lab uses genetic methods to clarify how allergic diseases develop, aiming to lead to the development of treatments. It also carries out research using the HLA peptide-binding assay.
*Illustrative imageGenetic analysis of allergic diseases
Using genome-wide methods that comprehensively examine the whole genome, the lab searches for genes involved in the onset of asthma, allergic rhinitis, hay fever, and food allergy. It also combines other methods such as gene expression analysis, aiming to contribute to personalized medicine.
*Illustrative imageSearching for antigenic peptides involved in disease
Using the HLA peptide-binding assay, the lab identifies antigenic peptides related to the onset of disease. It studies peptides related to the immune response to hepatitis B virus, allergen immunotherapy, drug hypersensitivity, and tumor antigens.
MembersFaculty
The members of the Genetic Medicine Lab consist of faculty, technical staff, a secretary, and PhD, master's, and undergraduate students.
- ProfessorEmiko Noguchi
- Assistant ProfessorHiroko Miyadera
VoicesStudent voices
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Report an errorAbout the images
The top and research theme images are illustrative and were not taken at the lab. They are cropped from Wikimedia Commons images. Cropped CC BY-SA images are provided under the same CC BY-SA license as the original (version shown on each line).
- Top image: “DNA sequencing” Linda Bartlett (Photographer) / Public domain (cropped)
- Genetic analysis of allergic diseases: “DNA-Sequencers from Flickr 57080968” Flickr user jurvetson / CC BY 2.0 (cropped)
- Searching for antigenic peptides involved in disease: “Peptide synthesizer” Michael Pereckas from Milwaukee, WI, USA / CC BY-SA 2.0 (cropped)
- Related lab (Neurophysiology Lab): “Tektronix 2467 analog oscilloscope (350 MHz)” Department of Energy. National Nuclear Security Administration. Sandia National Laboratories. 3/1/2000 / Public domain (cropped)
- Related lab (Anatomy and Embryology Lab): “Laboratory microcentrifuge tubes and pipette tips 01” Gannu03 / CC BY-SA 4.0 (cropped)
- Related lab (Molecular Parasitology Lab): “Trypanosoma brucei brucei SEM” Sue Vaughan / CC BY 4.0 (cropped)
- Related lab (Applied Medical Physics Lab): “8th CES and 8th MDG maintain nuclear and radiation emergency response readiness (9330029)” U.S. Air Force photo by Senior Airman Karissa Dick / Public domain (cropped)
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