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115 labs · 0 student voices
Faculties at University of Tsukuba ›
Shoi Shi, Associate Professor
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The Shi-Iino Lab uses mice and ants to study biological phenomena including the sleep-wake cycle, learning and decision-making, and phenotypic diversification. In mice, the lab investigates the minimal molecular and neural units responsible for sleep and wakefulness, and seeks to determine how well conserved they are by comparing them with other species. In ants, which are social insects, the lab examines the process by which genetically uniform individuals diversify their phenotypes through acquired changes. The lab also uses data science and mathematical models to search for the principles underlying complex biological phenomena.
Sakiko Honjoh, Assistant Professor
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The Honjoh Lab uses mice to study the mechanisms and functions of sleep. Its goal is to answer the fundamental question of why sleep is necessary, even though a sleeping animal cannot protect itself from external enemies and cannot study. The lab focuses in particular on non-REM sleep, the deep sleep that accounts for 80% of sleep. To join as a student, one must enroll in a graduate school at the University of Tsukuba; undergraduate students can take part as part-time research assistants.
Kenji Irie, Professor
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The Molecular and Cellular Biology Lab uses budding yeast, a eukaryotic model organism, to elucidate the regulatory mechanisms of biological phenomena, aiming to contribute to medicine and healthcare. The lab works on post-transcriptional regulation of gene expression, the signaling mechanisms that control the endoplasmic reticulum (ER) stress response, and the mechanisms of gamete formation. Undergraduate students can join through graduation research in the College of Medical Sciences and the College of Biological Sciences, or through laboratory training in the College of Medicine. On the lab's website, it is introduced under the name "Irie Lab."
Makoto Kobayashi, Professor
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The Molecular Developmental Biology Lab seeks to understand biological phenomena such as development, cell differentiation, disease, and aging through how genes function (gene expression). Its central focus is the mechanisms that determine cell fate and the mechanisms that respond to stress. For its research, the lab uses zebrafish, a fish that is amenable to genetic approaches and from which large numbers of individuals can be readily obtained. The lab's website also introduces it under the name "Kobayashi Lab."
Ken Nishimura, Professor
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The Gene Regulation Lab studies gene expression, which lies at the foundation of biological phenomena, using biochemical and molecular biological methods. It investigates transcription factors involved in transcriptional regulation, structural remodeling of chromatin (the site of transcription), and the mechanisms of iPS cell induction. As one of its research topics, the lab also studies how brown adipocytes and beige cells differentiate, aiming to contribute to solving obesity. The lab's website states that it provides careful, individual guidance to each graduate student, regardless of which university or department they come from.
Yuichi Shichino, Professor
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The RNA Biochemistry Lab studies a wide range of phenomena involving RNA. In particular, it focuses on translation, the synthesis of proteins from the information in mRNA, and aims to comprehensively understand when, where, and how it takes place. Making full use of genome-wide analysis with next-generation sequencers, everyone in the lab aims to become a researcher who can do both biochemical and molecular biological experiments and computational analysis. The lab was newly established in September 2025 and began full-scale research activities at the University of Tsukuba in April 2026.
Hiromi Yanagisawa, Professor
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The Yanagisawa Lab studies how cells respond to changes in their surrounding environment (the extracellular environment), focusing on vascular cells and tissue stem cells. Building on knowledge and experimental systems related to the extracellular matrix, the main component of the extracellular environment, the lab aims to clarify the molecular mechanisms of cellular responses to environments that change with aging and disease. To lead to new diagnostic technologies and the discovery of therapeutic targets, the lab also collaborates with researchers in imaging, bioengineering, and glycoengineering. On the lab's website, it is presented under the name "Hiromi Yanagisawa Lab."
Masayuki Masu, Professor
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The Masu Lab, part of the Molecular Neurobiology group, aims to clarify the molecular mechanisms that build neural circuits. Brain function rests on neural circuits formed during the fetal period, but how these circuits form is still not well understood. The lab studies the molecules and genes that control the process from neuronal differentiation through axon guidance and the formation of specific synapses to the acquisition of neural function. Based on molecular biology, the lab uses developmental engineering techniques in mice and zebrafish.
Michael LAZARUS, Professor
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The Lazarus-Oishi Lab studies the mechanisms that regulate sleep, as well as drug discovery, centered on the brain pathways linking sleep, wakefulness, and motivation. Using mice, the lab investigates how the caffeine in coffee and tea promotes wakefulness and how sleep affects immunity. In its research on sleep and motivation, the lab combines techniques for manipulating neural activity with light or drugs with in vivo imaging. The lab is located in the International Institute for Integrative Sleep Medicine (WPI-IIIS) at the University of Tsukuba and is jointly led by Professor Lazarus and Associate Professor Oishi.
Tsuyoshi Saitoh, Associate Professor
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The Medicinal Chemistry Lab (Saitoh Group) conducts research aimed at creating innovative molecules that contribute to biology and medical science, with chemistry as its foundation. Using GPCRs (G protein-coupled receptors), which are common drug targets, as a key theme, the lab carries out drug discovery research and chemical biology research on artificially controlling GPCR function. Based on the principle of "controlling living systems at will with chemistry," the lab values the curiosity behind the thought "I want to make a molecule like this!" On the lab's website, it is presented under the name "Kutsumura-Saitoh Lab."
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